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Biomedical subjects

J Barrier

Publications and source records attributed to J Barrier.

At least 109 records · Page 6Linked to original sources
PubMed1981

[beta-Lipoprotein serum levels in the months preceeding pregnancy toxemia and its relationship with the Cetrimonium test (author's transl)].

beta-Lipoprotein determination and selective serum protein precipitation with Cetrimonium bromide (Badin's Cetrimonium test) were carried out retroactively (after delivery) on sera selected out of 700 sera collected from women at 4-5 months and 6-7 months of pregnancy. The selected sera were those from 36 women in the first group and 37 in the second group, who had ended pregnancy with toxemia. The sera were matched to sera collected at the same period from women whose pregnancy had been normal until the end. In both the 4-5 month and the 6-7 month groups, women with toxemia at the end of pregnancy had significantly higher levels of beta-lipoprotein and higher Cetrimonium tests but the two data were not correlated. The information they provide on the abnormal condition preceeding toxemia symptoms are different : hyperlipoproteinemia would be a predisposing factor and the Cetrimonium test an evidence of some latent inflammatory process.

Cetrimonium↗
PubMed1980

[Automatic measuring of uterine activity in labour. The relationship between this new parameter, fetal cardiac rhythm and the state of the infant at birth].

In 163 cases uterine activity in labour was measured in 15 minutes periods, thanks to a new monitoring apparatus that works out the sum of the areas of uterine contraction (A U 15). In this way a regular statistical estimation of labour is given in kilopascals x second. The fetal state during labour and at birth is studied as a function of this new parameter. The following important therapeutic consequences can be derived from it: 1) Uterine activity should be damped down when this exceeds 1,500 kilopascals x second over 15 minutes. In fact, fetal cardiac rhythm alterations occur very frequently in these cases during the first stage of labour (55% of cases). 2) In labour it would seem to be worth while, if caesarean operation has not been judged to be necessary, to deliver the baby by instruments (to lessen the length of time of expulsion) when the mean of uterine activity over the 15 minutes (m A U 15) has exceeded 1,500 kilopascals x second, if this has been associated with even the smallest variations of the heart rate during the first stage of labour. In fact, a low apgar score and an acidotic pH occur frequently in these cases.

Apgar Score↗
PubMed1980

[Suppurative endometritis of a pregnancy. A diagnosis made during a caesarean operation (author's transl)].

An endometritis with abscess formation in pregnancy is very rare. A case that was discovered during a caesarean operation is described. The diagnosis is difficult because there is not much in the way of symptoms. The aetiology could be an infection of the cervix and vagina, a long-standing endometritis or a maternal extra-genital infection. Apart from antibiotic therapy the best treatment seems to be as conservative as possible.

Cesarean Section↗
PubMed1979

[Lung cancer with elevated amylase activity. One observation with study of amylase's isoenzymes (author's transl)].

Amylase is composed by two isoenzymes groups: pancreatic or salivary type. This last part can be increased in many diseases. A case of lung cancer with elevated amylase activity in blood, urine and pleural fluid is reported in a 74-year-old man. This increase was due to salivary type isoamylases with an unusual component which disappeared by neuraminidase treatment. The significance and the origin of this hyperamylasemia with non pancreatic cancer are discussed.

Adenocarcinoma↗
PubMed1979

[Acute agranulocytosis after treatment by levamisole. 2 cases (author's transl)].

We describe two patients who had a typical levamisole-induced agranulocytosis and a severe infection; the view of other cases found in the literature shows a fundamental fact: the complication can occur after a variable time of prescription (from thirteen days to eleven months), continuous or intermittent. The accidents are imprevisible, and circonspection must be used, not for its antihelminthic properties, but for its prolonged use for immunological purposes, even if some authors have not observed any cases of agranulocytosis in large series. Naturally, the purpose is quite different in the case of a severe rheumatoid arthritis or inesthetic warts, and our two observations are very demonstrative. Mechanism of agranulocytosis has not been totaly clarified: we have observed biological stigmates of immunological process against levamisole (responsible of agranulocytosis?), but essentially medullary lesions (successive regenerative aspects and necrosis) as has been described with pyramidon, and this could explain why the other blood cells are affected in an apparently isolated agranulocytosis.

Acute Disease↗
PubMed1979

[The advantages and disadvantages of ultrasound scanning in the diagnosis of ectopic pregnancies (author's transl)].

There is no need any more to demonstrate the value of echotomography in the diagnosis of extra-uterine pregnancies. All the same, the authors want to point out in the light of two cases they have had the rare, but real risk of errors made because of deficiencies in echography, which because they have excluded extra-uterine pregnancy lead to a delay which can be considerable in diagnosis. The first section deals with the features of diagnosis to be considered in extra-uterine pregnancy (an empty uterine cavity or, on the other hand, the presence of a pregnancy sac in the uterus; rarely the picture of an ovum in an ectopic position, but more often the picture of a haematosalpinx or a haematocoele). The risks of making mistakes because of insufficient information are described. These mistakes can be of serious consequence because they delay using the laparoscope (particularly likely to occur if there is the presence of a pseudo-sac of pregnancy due to separation of the decidua). Finally, the risks of making mistakes by having too much information are spelt out. These are less serious because they do lead to the use of the laparoscope. (They are wrongly diagnosed ovarian cyst, hydrosalpinx and double uterus.) In the last section the statistics given by various authors are reviewed.

Adult↗
PubMed1979

[Pyoderma gangrenosum and haemopathy. Report of three cases (author's transl)].

The authors report three personal cases of phagedenic pyoderma associated with hemopathy. Studying twenty-five other cases, described in the reviews, the question can be debated on three levels: 1) The clinical characteristics of hemopathic pyoderma remain non-specific. However blisters, pustules, and even vegetating lesions occur very often; 2) the etiology of hemopathy is subject to change; acute leukaemia or myeloproliferation syndrome. During the polyglobulars associated with pyoderma, anemia and myelofibrosis appear quite constantly; 3) finally on the pathogenic level, the recent works tend towards the hypothesis of a damage in the functioning of the polymorphonuclears hence displaying the increase in the inflammation during phagedenic pyoderma.

Adolescent↗