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Biomedical subjects

J Barrier

Publications and source records attributed to J Barrier.

At least 91 records · Page 5Linked to original sources
PubMed1982

[Aphthous hepatic lesions and Behçet syndrome].

The case of a twenty-one-year-old man who was hospitalized for unexpected bilateral phlebitis of the lower limbs is reported. Clinical features suggested a systemic disease, especially Behçet disease although the classical triad was lacking. Laparoscopy showed two lesions identical to canker sores on the hepatic capsule. There were no biological hepatic disorders and histological examination of a needle biopsy specimen was normal. This clinical report is additional evidence in support of the idea that Behçet is syndrome is a systemic disease.

Adult↗
PubMed1982

The use of Doppler flow studies in the diagnosis of giant cell arteritis. Selection of temporal artery biopsy site is facilitated.

Sixty patients, for whom a diagnosis of giant cell arteritis (GCA) was clinically suspected, underwent Doppler study as a method of guiding temporal artery biopsy. In group A (23 patients with normal Doppler results), only one had a positive histological lesion. In group B (14 patients with discrete Doppler abnormalities), none had inflammatory lesions. Twelve of the 23 patients in group C (stenosis or thrombosis) had a biopsy result corresponding to GCA. Forty-three percent of the patients in group C had degenerative arterial lesions leading to a decrease in blood flow. There is a small probability, according to this preliminary study, of diagnosing GCA by artery biopsy even when findings from the ultrasonic examination are normal or only slightly irregular. However, a negative Doppler result should in no case exclude a biopsy if the clinical picture is suggestive.

Aged↗
PubMed1982

[Pulmonary infection with Pasteurella multocida in an immuno-deficient patient (author's transl)].

A seventy-seven-year-old woman, under intermittent treatment with chlorambucil for chronic lymphocytic leukemia, developed acute pneumonia (diffuse interstitial pneumonitis) due to Pasteurella multocida. No direct traumatism had been caused by her cat. Bacteriologic study material was obtained by guided transtracheal distal bronchial brushing and washing. Therapy with tetracyclin was rapidly successful. Pasteurella multocida is an opportunistic organism which can be responsible for severe infections in high-risk patients.

Aged↗
PubMed1982

[Comparative study of the bacteriologic value of samples taken by transtracheal aspiration or fiberoptic bronchoscopy].

To evaluate two methods of obtaining lower respiratory tract secretions, fiberoptic bronchoscopy (FB) and transtracheal aspiration (TA) were performed in ten patients. FB used an open-end brush-in catheter. TA was performed as described by Pecora. TA gave significantly better sensitivity and specificity (3/5 and O false positive results respectively) than FB (2/5 and 5 false positive results). TA gives specimens which reflect the bacterial flora of the lung more reliably than those taken during FB.

Biopsy, Needle↗
PubMed1982

[Pulmonary fibrosis in ankylosing spondylitis. Five new cases (author's transl)].

The most common thoracic finding in ankylosing spondylitis (AS) is ankylosis of the costovertebral joints with severe limitation of chest expansion inducing a restrictive syndrome pleural and pulmonary fibrosis can occur during the course of the disease. One-hundred record of patients with AS were reviewed. Five had pleuro-pulmonary involvement. This always included pachypleuritis, usually apical. Roentgenographic pulmonary changes were infiltrates or fibrobullous lesions. Pulmonary function tests showed restriction in four cases, obstruction in one case, and a decreased diffusing capacity in all five cases.

Adult↗
PubMed1982

[Anatamo-pathologic aspects of gold-salt induced cholestasis. Report of two cases with ultrastructural study (author's transl)].

The authors report two cases of gold-salt-induced cholestasis. They make a review of the thirteen cases previously related in the literature ; the cholestasis was constant, the hepatocytic necrosis was unusual and the gold-salts were difficult to visualize in the liver biopsy and more especially at the ultrastructural level. The immunological mechanism of hypersensibility is well established ; the possibility of an associated hepatotoxicity is debated.

Aged↗
PubMed1982

Guided transtracheal distal pulmonary brushing-washing: diagnosing acute pneumonia in high-risk patients.

Transtracheal brushing-washing of distal pulmonary lesions was performed in 20 patients. Specimens were obtained by brushing and washing through a catheter placed in the pulmonary lesion with the aid of a guide. In nine patients pathogenic organisms were isolated. In the other 11 patients infectious studies of the specimens were negative, five of the patients (true-negatives) showing no infection and six (false-negatives) showing infection. Serious complications were uncommon, but one patient, who had diffuse intravascular coagulation, died. This procedure seems to represent an advance over transtracheal aspiration and is an effective alternative to such invasive methods are transthoracic lung aspiration and pulmonary biopsy.

Adult↗
PubMed1982

[Complementary studies in acute bronchopulmonary infections except tuberculosis].

Development of a strategy for the investigation of pulmonary infectious disease is aimed at identifying the organism responsible for the infection in order to prescribe the appropriate antibiotic therapy. Factors involved in the choice of a method are the underlying condition (healthy, high risk or immunodepressed subject), the type of infection (primary, secondary), the technical abilities of the medical and bacteriological team and finally the value of the different techniques of isolation. The latter must provide a specimen which is not contaminated by the oropharyngeal flora. Their reliability involves definition of a reference method which can be used to test the other techniques in comparison, and requires comparison of the bacteriological results obtained with clinical and radiological data as well as the results of the resultant therapeutic decision. Indirect methods of investigation (blood cultures, serological studies) are relatively unfruitful. Criteria of value of direct methods of investigation are defined and applied to each method (expectoration, transtracheal aspiration, bronchial fibroscopy, transparietal puncture). On the basis of data in the literature and their own results, the authors undertake an analytical then comparative (in a given patient) study of the different methods, and identify their indications.

Biopsy↗
PubMed1982

[Pneumococcal peritonitis. An unusual diagnosis in gynecology].

The authors, having had a case of primary pneumococcal peritonitis, review the features of this pathological condition which has become rare, and of gynaecological pneumococcal infections. Pneumococcal peritonitis presents as a very serious peritonitis and the usual diagnosis that is first made is peritonitis due to appendicitis. Pneumococcal peritonitis can be primary but it is possible that it is often secondary to genital pneumococcal infections. Treatment should always be by laparotomy to confirm the diagnosis, with a peritoneal toilet which is needed in order to stop a pelvic abscess developing. Antibiotics, which are usually of the penicillin group, should be given for at least 15 days. The treatment can be varied in those rare cases where cirrhotic ascites or serious nephrotic syndromes develop in children. Putting in drains and removing the appendix when it is normal are both useless.

Adult↗
PubMed1981

[Virilising luteoma during pregnancy. A case report and a review of the literature (author's transl)].

Luteoma in pregnancy is a rare tumour (about 100 published cases) and it is rarely associated with signs of virilisation (28 published cases). A visiting luteoma in pregnancy in primigravid woman of 27 years of age is reported and compared with other cases in the literature. A study of the androgen secretions before and after pregnancy and especially the levels of androgens in the peripheral blood, the ovarian vein and in the tumour ware carried out so that metabolic pathways of the production of the androgens could be worked out. The particular circumstances of the unexpected appearance of this luteoma during an H.C.G. stimulation test (Human Chorionic Gonadotrophin) gives an opportunity to define the role of this hormone in its occurrence. Finally, a review of the literature makes it possible to draw up a history of the usual behaviour of these virilising luteomas in pregnancy: they usually show up in the second trimester of pregnancy, and the overriding role is played by testosterone with virilisation of female fetuses.

Adult↗