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Biomedical subjects

J Banks

Publications and source records attributed to J Banks.

126 records · Page 7Linked to original sources
PubMed1970

Plaque formation by Chlamydia in L cells.

Chlamydiae were found capable of producing plaques in several cell lines. Mouse fibroblast cells, L-929, proved the most sensitive to infection and yielded plaques of the highest clarity. Assay of chlamydial infectivity by plaque titration was at least as sensitive as egg ld(50) determination. Among chlamydial isolates of avian, mammalian, and human origin, only slow-growing trachoma-inclusion-conjunctivitis agents did not produce plaques. The plaque assay is highly sensitive, reproducible, and offers a potential tool for investigations requiring accurate measurement of small changes in chlamydial infectivity.

Journal Article↗
PubMed1970

Plaque reduction technique for demonstrating neutralizing antibodies for Chlamydia.

Some members of the genus Chlamydia (Bedsonia or psittacosis-lymphogranuloma venereum-trachoma-inclusion conjunctivitis group of microorganisms) produce plaques in monolayers of mouse fibroblast (L-929) cells. Hyperimmune chicken antisera may be capable of specifically reducing plaque counts. When the test was applied to chlamydiae isolated from avian species, the results indicated that different isolates with a common source had similar antigenic reactivity. The plaque reduction test is a potentially useful method for serotyping chlamydiae. The difficult aspect of the method appears to be a readily reproducible means of producing neutralizing antiserum.

Journal Article↗
PubMedDate not supplied

Bileaflet valve replacement: complications and costs.

A meta-analysis of the available literature on the CarboMedics and St. Jude Medical valves was conducted to compare their clinical performance. Frequency of valve-related complications for aortic, mitral, and double-valve replacements served as a measure of performance. An economic model was created to estimate the economic impact of valve-related complications. Overall, fewer events occurred with the St. Jude Medical valve than with the CarboMedics valve. As a result, use of the St. Jude Medical valve is expected to save up to $13,201 over 10 years.

Adolescent↗
PubMedDate not supplied

An epidemiological and clinical investigation of pulmonary function and respiratory symptoms in patients with rheumatoid arthritis.

Several studies have investigated lung function in patients with rheumatoid arthritis but have reached different conclusions. The main discrepancy has been between airways disease reported in 38-65 per cent of patients and interstitial pulmonary disease reported in 30-41 per cent. These variable results have probably arisen because specific lung disorders have often been diagnosed on the basis of non-specific tests of lung function which, when considered in isolation, are subject to different interpretations. We adopted a combined epidemiological and clinical approach to investigate lung function and respiratory symptoms in patients with rheumatoid arthritis. Epidemiological data showed that rheumatoid arthritis is associated with a mild restrictive lung defect with reductions in mean FEV1 and FVC of 0.26 l and 0.29 l respectively and a normal FEV1/FVC ratio. The reduction in mean maximum mid-expiratory flow rate of 0.34 l/s could be explained on the basis of lung restriction and there was no evidence of widespread airways dysfunction other than that which could be explained by cigarette smoking. The clinical study showed that abnormal lung function tests in individual patients were caused by a heterogeneous group of conditions which are frequently caused, or exacerbated, by cigarette smoking. Cigarette smoking, and not the rheumatoid process, was the most frequent cause of abnormal lung function in rheumatoid arthritis.

Adolescent↗
PubMedDate not supplied

Flexible monitoring in the management of patient care processes: a pilot study.

This article describes a study conducted on the internal medicine, general surgical, and vascular wards of a large metropolitan hospital to assess the impact of a networked monitoring system and portable patient monitors. This pilot study was developed to address the need of hospital patients who require continuous noninvasive vital signs monitoring (including heart rate, noninvasive blood pressure, pulse oximetry, cardiac waveform monitoring) with the addition of surveillance from a cardiac intensive care area. Data were collected from 114 patients over a 3-month period to identify a patient group that could be managed appropriately under the new system and to determine the effect that flexible monitoring had on patient care management. Findings include identification of a specific patient group that can be managed successfully outside the cardiac intensive care area using this system. Other findings suggest a way to improve the management of patient monitoring in the general ward areas.

Aged↗
PubMedDate not supplied

The chronically ill grandparent in minority multigenerational family households: problems and solutions from three points of view.

The Interactional Model of Family Systems was used as a basis for exploring the problems of the chronically ill grandparent from three points of view: the elder family member, the adult child, and the grandchild. A descriptive correlational study was utilized to collect data on a purposive sample of 10 minority families recruited from the Montgomery County Council of the National Council of Negro Women, personal contacts of the investigators, and referrals from a family physician who treats the chronically ill elder members. Data was obtained on the family environment, perceived support, physical health, and a variety of open-ended items dealing with specific difficulties and coping strategies. Findings identified ambivalent feelings, contradictory statements, and some dissatisfaction about their relations with other family members, not feeling needed, not having enough to do and feeling lonely. This information can be useful in designing and implementing a counseling intervention model for groups of multigenerational families who have similar situations and needs.

Adaptation, Psychological↗