Search PubMed⌕ Search

Biomedical subjects

J Bancroft

Publications and source records attributed to J Bancroft.

At least 91 records · Page 5Linked to original sources
PubMed1983

Changes in erectile responsiveness during androgen replacement therapy.

Erections in response to erotic films and fantasies were measured in eight hypogonadal men, with and without androgen replacement, and eight age-matched controls. Erections to films in the hypogonadal men did not differ from those of the controls and were not affected by androgen replacement. Erections to fantasy were significantly smaller and slower to develop in the hypogonadal men and did show significant improvement during androgen replacement. These preliminary results suggest that erections to certain types of stimuli are relatively independent of androgens, whereas the response to fantasy may be androgen dependent. The implications of these findings are discussed.

Adult↗
PubMed1983

Mood, sexuality, hormones and the menstrual cycle. I. Changes in mood and physical state: description of subjects and method.

Mood and physical symptoms through the menstrual cycle were investigated in 55 women with normal ovulatory cycles. One-third had attended a clinic with severe premenstrual syndrome (clinic PMS group); the remainder were volunteers either with a history of PMS (non-clinic PMS group) or without (no PMS group). Each cycle was divided into six hormonally distinct phases on the basis of repeated hormone measurement. Self-ratings of "well-being" reached their maximum in the late follicular phase, declining throughout the luteal half of the cycle. This pattern was pronounced and statistically significant in the "clinic" and "nonclinic PMS" groups. In all three groups, "physical distress" increased during the second half of the cycle to reach a maximum in the late luteal phase. A clear temporal relationship was therefore demonstrated between mood, physical state, and hormonal phases of the cycle. It remains uncertain whether changes in the "clinic" group were extreme forms of a normal pattern or were qualitatively different.

Adult↗
PubMed1983

Mood, sexuality, hormones, and the menstrual cycle. II. Hormone levels and their relationship to the premenstrual syndrome.

In women with premenstrual syndrome, negative changes start soon after ovulation gradually increasing as the corpus luteum develops, and reach a maximum during the last 5 days of the luteal phase. They decline rapidly once menstruation starts, disappearing within one or two days of ovarian steroids reaching baseline levels. Positive moods are at maximum when preovulatory estradiol reaches its peak. A comparison of hormone levels in women with high and low degrees of cyclical mood change showed no difference in progesterone, estradiol, testosterone, or androstenedione.

Adult↗
PubMed1983

Mood, sexuality, hormones, and the menstrual cycle. III. Sexuality and the role of androgens.

Sexual interest and activity at different stages of the menstrual cycle was recorded by 55 women with normal ovulatory cycles. In women with marked cyclical mood change, there was an associated cyclical pattern of sexual feelings. Subjective sexuality independent of mood change, was maximal in the mid-follicular (i.e., postmenstrual) and late luteal (i.e., premenstrual) phases. Sexual activity was maximal in the mid-follicular phase. There was no evidence of a periovulatory increase in sexual interest or activity. Mean testosterone levels were correlated with masturbation frequency but not with sexuality involving the partner. A weak association between testosterone and life style (i.e., in full-time work or a housewife) was also evident.

Adult↗
PubMed1983

Why people take overdoses: a study of psychiatrists' judgements.

There was considerable agreement between 50 psychiatrists in their choices of reasons to explain patients' overdoses after reading transcripts of interviews with self-poisoning patients. The reasons attributed in each case were similar to those chosen by three psychiatrists in an earlier study. Most psychiatrists chose more than one reason for each case. Multidimensional scaling analysis of the psychiatrists' choices across the cases suggested four groups of reasons: (a) directed at some significant person; (b) help-seeking; (c) self-referring; (d) suicidal intent. Future research could include the use of shorter lists of reasons, and should be directed particularly towards assessing the intended and actual effects of self-poisioning behaviour on significant others.

Adolescent↗
PubMed1982

The behavioural effects of testosterone undecanoate in adult men with Klinefelter's syndrome: a controlled study.

The behavioural effects of exogenous testosterone in men with marginally low circulating androgen levels were investigated. Four adult men with Klinefelter's syndrome, low normal testosterone levels and normal sexual activity and interest were given testosterone undecanoate (TU 160 mg daily by mouth; Organon International) and placebo using a double blind cross-over design. A modest increase in sexual interest was observed during TU administration compared to placebo, though there were no effects on self-reported mood or energy, or on erectile responsiveness in the laboratory. Increase in circulating hormone levels during TU administration was more marked for DHT than for testosterone. The possible implications of this are discussed.

Adult↗
PubMed1982

The personality and psycho-sexual development of boys with 47 XXY chromosome constitution.

Twelve XXY boys identified at birth in a population screening study were followed up at a mean age of 16.7 yr and compared with a control group of chromosomally normal boys matched for age and social class. Assessment of personality and psycho-sexual development showed the XXY boys to be more timid and less self-confident and to have problems in relating to their peer group than the controls. They also showed some evidence of delayed or impaired development of sexual interest. In general, the differences were not marked. Possible causes for these differences and potential methods of preventing them are discussed.

Adolescent↗
PubMed1982

Klinefelter's syndrome in adolescence.

Twelve boys with Klinefelter's syndrome (47,XXY) identified by sex chromatin screening at birth were examined at between ages 16 and 18 years, together with 12 controls matched for social class and birth order from the same newborn population. Physical examination, psychometric assessment, personality, and degree of psychosexual development were assessed without knowledge of the karyotype. Anthropometry showed increased leg length and decreased head circumference in the XXY boys. Gynaecomastia was present in 4 boys, and testicular volume was reduced in the majority but one boy had normal sized testes. On the Wechsler intelligence scale there was a significant reduction in verbal score but not in either performance or full-scale score compared with the controls. Although appreciable differences were found in growth, personality, intelligence test scores, and psychosexual development, these were of small degree.

Adolescent↗
PubMed1981

The effects of sterilisation: a comparison of sterilised women with the wives of vasectomised men.

In a follow-up study, women sterilised by tubal diathermy were compared with a matched group of wives of vasectomised men. Semi-structured interviews were given to a random sample drawn from a representative population. The couples were young with small families and did not have a high proportion of unplanned pregnancies or terminations. They had previously used contraception, mainly the pill or sheath. Most couples were entirely satisfied with the operation. Both groups showed an increase in pre-menstrual symptoms but there was only slight evidence that menstrual loss was affected by female sterilisation. The vasectomy couples had a higher frequency of sexual intercourse, few sexual problems and tended to have more satisfactory marriages. They had had more discussion of their decision to have the operation and the implications of counselling are considered.

Coitus↗
PubMed1981

Domiciliary and out-patient treatment of self-poisoning patients by medical and non-medical staff.

In a study of domiciliary and out-patient treatment of self-poisoning patients, using a brief problem-orientated approach, it was found that domiciliary treatment resulted in much higher attendance rates but no difference in outcome. Patients who completed out-patient treatment had a better outcome than those who failed to attend treatment sessions. Completion of out-patient treatment was more frequent among higher social class patients. Domiciliary treatment may be more appropriate in some cases for married patients and for those of lower social class. Medical and non-medical staff proved to be equally effective therapists. Future research should be concerned with evaluation of alternative methods of provision of help and further identification of patients who are most likely to benefit from treatment.

Adult↗
PubMed1981

Androgen replacement with oral testosterone undecanoate in hypogonadal men: a double blind controlled study.

The effects of androgen withdrawal and replacement were investigated in six hypergonadotrophic and six hypogonadotrophic men with hypogonadism. A double blind cross-over design was used comparing testosterone undecanoate (T.U., Organon International), 160 mg daily by mouth, with placebo. There was a significant effect of T.U. on all measures of sexual interest and behaviour. Sexual interest increased within the first week of T.U. administration, ejaculation usually returning within the second week. Behavioural responses were similar in the hyper- and hypogonadotrophic groups. The rise in plasma testosterone during T.U. administration was modest, not reaching the normal range in several cases. 5 alpha dihydrotestosterone rose more substantially. There was a significant fall in sex hormone binding globulin, a rise in oestradiol and no significant change in gonadotrophin concentrations during T.U. administration.

Adult↗
PubMed1980

Diabetic impotence.

Explore the source record for details and available documents.

Diabetes Complications↗