Search PubMed⌕ Search

Biomedical subjects

J Ameille

Publications and source records attributed to J Ameille.

66 records · Page 4Linked to original sources

[Cytology of broncho-alveolar lavage samples in sarcoidosis (author's transl)].

The cytology of samples from broncho-alveolar lavage was studied in 18 patients with stage I or II sarcoidosis, three of whom were smokers (stage II). Cell content was 213 +/- 111.10(3)/ml with 30.8 +/- 15.7 p. cent of lymphocytes for stage I, and 338 +/- 98.10(3)/ml with 34.1 +/- 8.7 p. cent of lymphocytes for stage II patients who were non smokers. In the three patients in stage II who smoked, cell content was 206 +/- 107.10(3)/ml with 15.3 +/- 9.4 p. cent of lymphocytes. Measuring angiotensin conversion enzyme in 12 cases demonstrated elevated (7 cases) or normal (5 cases) levels unrelated to the radiological stage or the lymphocytosis. Diagnosis was confirmed by the presence of characteristic epithelioid granulomas in all cases, in 14 patients after trans-bronchial pulmonary biopsy. In comparison, cell content in 3 cases of extrinsic allergic alveolitis associated with histologically confirmed granulomas was 690 +/- 120.10(3)/ml with 50.3 +/- 10.7 p. cent of lymphocytes, and in 9 cases of different types of intestinal affections was 327 +/- 157.10(3)/ml with 6.33 +/- 7 p. cent of lymphocytes. Constantly elevated lymphocytosis in sarcoidosis constitutes a diagnostic aid; perhaps it can be used during follow-up examinations as a means of assessing progression of the disease. No correlation with the conversion enzyme was noted.

Adult↗

[Acute and chronic tuberculosis of the liver and hematopoietic system (author's transl)].

The authors report three cases of tuberculosis affecting the liver and hematopoietic system. The difficulty in diagnosing the chronic progressive forms of the disease and the severity of the acute forms is stressed. Liver biopsy is considered to be the most effective examination for confirming the nature of the disease. Acute and chronic forms can also be distinguished histologically, as the former produce nectotic lesions rich in tubercle bacillus but with only slight surrounding cellular reaction, while the latter lesions are productive and are rich in epithelioid histocytic cells.

Aged↗

Epidemiologic investigation of respiratory effects related to environmental exposure to asbestos inside insulated buildings.

The respiratory effects of environmental pollution by asbestos inside university buildings were studied by comparing radiographic, clinical, and functional parameters among three groups of workers with different levels of exposure. Eight hundred and twenty-eight (828) people who worked for at least 15 yr in asbestos-insulated buildings and who were without known occupational exposure to asbestos (environmentally exposed group [EE]) were compared to a group of 252 workers with occupational exposure (occupationally exposed group [OE]), used as positive control; and to a group of 350 people with no known exposure to asbestos (nonexposed group [NE]), within the same university. After adjustment for confounding variables, no differences could be seen between groups EE and NE. Group OE exhibited a higher prevalence of pleural changes and lower lung functions than groups EE and NE.

Adult↗

[Hiccup caused by epigastric compression in a hemiplegic patient].

The authors report the case of a patient with permanent, refractory hiccup, resistant at all classical treatment methods. Hiccup was due to compression of the epigastric region by the left fist of the patient immobilised by a spastic hemiplegia. Passive mobilisation of the diseased upper limb resulted in the disappearance of hiccup.

Abdomen↗

[Effect of inhalation of hair spray on the rat respiratory system].

A study of the effects of inhaled hair-spray was performed on 118 specific pathogen free male Wistar rats (71 test animals and 47 controls). Rats were exposed for 5 min, three times a day, five days per week, during one to eight weeks, in two plexiglas chambers, one for controls and one for test animals. The chambers were 20 1 in size, but only the noses of the animals were exposed to ambiant air or to a hair-spray aerosol polluted atmosphere. In the test chamber, the hair-spray was aerosolized for 30 s at the beginning of each exposure, using about 30 g of nebulized product. This hair-spray amount was high, although non-lethal (70% of DL0, 45% of DL50 and 26% of DL100). The hair-spray exposed rats exhibited significant modifications in the antixenic defence mechanisms of their respiratory system: diminished ciliary activity of the tracheal epithelium (-26%), increased number of harvested pulmonary macrophages (+52%), but decreased phagocytic ability of these cells (-8%). However we did not observe histologic differences in the respiratory system of exposed and control rats.

Aerosols↗

[Computed tomography in thoracic pathology].

The fundamental principles of computed tomography (CT), its clinical applications and costs are presented followed by the indications and results in diseases of the mediastinum, the oesophagus, heart and great vessels, and the lung and pleura. The CT scan can give the precise localization and density of mediastinal tumours and be used to distinguish thymomas, goiters, lymph nodes, lymphomas, neurinomas and different bronchogenic and pleuropericardial cystic formations. The operability of oesophageal cancer can also be determined. In cardiovascular diseases, the CT scan is particularly useful to identify inborn anomalies, aneurysms, aortic dissection or caval compression or thrombus formation. In lung diseases, the indications for a CT scan are particularly important in bronchopulmonary cancer, tuberculosis, bronchopathies and chronic lung diseases. In bronchogenic cancer, for example, the CT scan is not only a major diagnostic tool but is also particularly useful in determining the prognosis and for following the effectiveness of treatment. The CT scan can be used to identify both effusions of liquid and gas as well as pleural reactions producing thick membranes of importance for both aetiology and later follow-up. Bronchectasis can be identified on serial sections where the degree of extension can be measured. CT scan is also indicated in patients with emphysema, both for evaluating extension and follow-up. Finally the indications and contraindications for interventional computed tomography, particularly in guiding needle biopsies, is presented.

Cardiovascular Diseases↗