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Biomedical subjects

J Aagaard

Publications and source records attributed to J Aagaard.

At least 91 records · Page 5Linked to original sources

An epidemiological case-control study of bladder cancer in males from a predominantly rural district.

A case-control study was performed on 165 male bladder cancer patients and an equal number of male control persons matched in age and geographic area. Thirty determinants of assumed importance were examined. A multivariate logistic analysis was performed. A significant increment in the relative risk (RR) for bladder cancer was associated with cigarette smoking (RR = 1.89), a history of prostatic surgery (RR = 2.38), nocturia (RR = 2.05), previous venereal disease (RR = 2.42), industrial work (RR = 1.82), work with oil or gasoline (RR = 2.71) and work with various unspecified chemical materials (RR = 1.58).

Adult↗

Serum levels of calcium and parathyroid hormone after subtotal thyroid resection for Graves' disease.

The following serum constituents were measured in 19 patients operated on for Graves' disease: calcium, protein, parathyroid hormone (PTH), alkaline phosphatase, thyroxine, triiodothyronine, free thyroxine index, and thyroid-stimulating hormone. Blood was sampled systematically on the day before and 5 days, 1 month, 2, 3, 4 and 6 months after operation. All patients were pretreated with antithyroid drugs, and 2 months before surgery levothyroxine was added. The study showed that the thyroid function was impaired for 3 months postoperatively. Serum calcium level was lowered in the same period. Serum PTH increased with decreasing serum calcium, and vice versa. The results support the theory that the transient fall in serum calcium level is due to lowered PTH sensitivity in bone tissue caused by temporary impaired thyroid function after surgery. On the other hand, a direct action of lowered thyroid hormone on bone tissue is also a possible explanation.

Adolescent↗

Social factors and life events as predictors for children's health. A one-year prospective study after discharge from hospital.

During a period of one year information concerning social background, life events and diseases of children (aged 1-14) admitted to a paediatric department had been obtained. One year after this index hospitalization, information concerning the children's present state of health was obtained. Forty (13%) had been readmitted to hospital during the follow-up year, and the parents of 72 children (23%) reported that their child's present state of health was poor. A multivariate predictor analysis was performed. The associations discovered suggest 1) that the selected social or psycho-social factors do not appear to be of considerable importance for prediction of readmission to hospital, 2) that "poor health" in the children has a very complex prediction pattern, partly due to disease variables, partly due to indices of unfavourable family background.

Adolescent↗

Recanalized umbilical vein in portal hypertension.

Experience with splenoportography suggests that patency of the umbilical vein occurs in about 9% of the patients with portal hypertension. A widely patent umbilical vein might serve as a decompressive portosystemic shunt. Percutaneous transhepatic portography was performed in 107 patients with cirrhosis of the liver and portal hypertension. A patent umbilical vein was found in 28 patients (26%). This finding significantly paralleled the number and size of other collateral veins, apart from gastroesophageal varices. No significant relation was found between umbilical vein patency and portal pressure, extrahepatic shunting, variceal bleeding, or ascites. It is concluded that a large patent umbilical vein does not effectively relieve portal hypertension, prevent gastroesophageal varices, or protect against variceal bleeding or ascites.

Adult↗

The role of endoscopic pancreatography in pancreatic ascites.

Pancreatic ascites due to chronic pancreatitis and pancreaticoperitoneal fistula in three patients is reported. The diagnoses were based on amylases in the ascitic fluid. An exact localization of the leakage of pancreatic juice by endoscopic retrograde pancreatography made a rational approach to therapy possible.

Adult↗

A clinical and socio-medical investigation of patients 5 years after surgical treatment for duodenal ulcer. I. Behavioural consequences and psychological symptoms.

Within the framework of the Aarhus County Vagotomy Trial a socio-medical interview investigation was performed. Ninety-one patients were asked to participate. Half of the patients had an ulcer history of more than 15 years. One fifth had experienced preoperative complications. Thirty-nine per cent of the patients showed changes in social activity according to Patrick's grading. Within work and leisure time significant improvements had taken place. Most of the patients with paid work were characterized by a high degree of satisfaction, conscientiousness, and stability at work. Symptoms indicating psychological impairment were commoner among the patients than in the background population. No accumulation of tobacco or alcohol abuse was found. The consumption of medicine was rather high. During the period of observation a decrease in the consumption of ulcer drugs, but not in other drugs, was noted. The frequency of sick days was rather high. The rate of consultations at the general practitioner did not differ from what would be expected. It is suggested that surgical cure of an ulcer only has some impact on the total life situation of the patients and that non-specific psychological symptoms in some patients may invalidate the overall result of treatment.

Activities of Daily Living↗

A clinical and socio-medical investigation of patients 5 years after surgical treatment for duodenal ulcer. II. Association of social and psychological factors with surgical outcome.

Within the framework of the Aarhus County Vagotomy Trial a socio-medical investigation was performed. Eighty-eight patients were interviewed. Data were collected concerning the patients' own assessments and several psychological symptoms. The interview also comprised questions about education, career, and personal and family problems. The surgeon's assessment, expressed by the Visick classification, was significantly correlated with the patients' assessments. In the analysis of predictors for surgical failure expressed by the Visick classification, age was the only significant predictor. Indicators of social or psychological stress showed a tendency towards association with an unfavourable outcome. No associations were found between the selected predictors and surgical failure expressed as recurrent ulcer. Patients classified as Visick III or IV had an accumulation of non-specific psychological symptoms indicating psychological impairment. It is suggested that evaluations of surgical outcome for duodenal ulcer consider both a specific surgical dimension and a subjective dimension expressed by the patients' judgements and/or expression of their health status.

Adaptation, Psychological↗

Bleeding duodenal varices demonstrated by transhepatic portography. Report of a case misinterpreted as Bleeding duodenal Ulcer.

Bleeding duodenal varices are a rare complication of portal hypertension. Upper gastrointestinal bleeding from other sources than varices is common in patients with cirrhosis. Most often the bleeding is misinterpreted as bleeding from duodenal ulcer, and the diagnosis is first apparent during emergency operation. From our experience with a case of bleeding duodenal varices we suggest that the diagnostic procedure of choice is percutaneous transhepatic portography.

Aged↗