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Biomedical subjects

Iu N Andreev

Publications and source records attributed to Iu N Andreev.

13 recordsLinked to original sources

[Value of contrast arthrography in the diagnosis of hemophilic arthropathy].

X-ray semiotics of changes in the roentgen-negative components of the knee joint at different stages of hemophilic arthropathy has been described basing on the study of 46 contrast arthrography ++ of the joint, and their correlation with the results of macroscopic and histological investigations of the tissues removed during surgery. Identification of the character of the damage in the soft-tissue and cartilage components of the joint is particularly important at the early stages of arthropathy, as it enables determining the optimum therapeutic tactics when the data of routine roentgenography give insufficient information, and changes in the bones are limited and, as a rule, reversible.

Adolescent

[Appearance of factor VIII inhibitors in various diseases].

Cases of hemorrhagic syndrome development due to the appearance of factor VIII inhibitors have been described in varying diseases. Clinical signs for the diagnosis and methods of combined therapy of such cases have been presented that are of great importance for practical use.

Adult

[The human herpesvirus type 6 (HHV-6) and its spread in Russia].

This is the first presentation of information on the circulation of human herpes virus type 6 (HHV-6) in the population of the mid-European part of this country. The results of the study indicate that HHV-6 is widely spread both among apparently normal people and among patients with different pathologies. The studies using immunofluorescence test showed that the percentage of HHV-6-infected subjects was practically similar among blood donors, patients with nasopharyngeal cancer, rheumatoid arthritis, hemophilia, and patients with transplanted kidney, varying from 34% to 49%. A significantly higher per cent (66%) and higher antibody titres to HHV-6 were detected in sera from patients with hemoblastoses. A high level of HHV-6 infection among patients with hemoblastoses was also confirmed by the results of immunoblotting showing a wider spectrum and higher intensity of the detectable proteins. It should be noted that the amounts of virus-specific proteins detectable by some sera showed individual variations indicating different levels of expression of viral proteins in different individuals.

Antibodies, Viral