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Biomedical subjects

I W Scopp

Publications and source records attributed to I W Scopp.

At least 37 records · Page 2Linked to original sources
PubMed1977

Antibiotics and the intraoral abscess.

Sensitivity tests were administered to determine the effectiveness of several antibiotics in the management of the oral abscess. Cultures were taken from 13 patients who were diagnosed as having either a periodontal or periapical abscess. Results revealed the following 1. The most effective antibiotic was Chloromycetin. Yet it was felt that its medical contraindications far outweigh its use by the dental practitioner. 2. Tetracycline was the least effective antibiotic. 3. Penicillin, because of its high potency against microorganisms of the dental abscess, should be considered the drug of choice. Its use, however, must be restricted to patients who give a negative history to allergies and/or asthma; when such a history is positive, erythromycin should be used. 4. Appropriate culture and sensitivity tests should be performed to determine the susceptibility of the causative organism(s) to the drug of choice.

Adult↗
PubMed1977

Tetracyclines: double blind clinical study to evaluate the effectiveness in periodontal surgery.

Twenty consecutive hospital patients who were to have periodontal surgery were assigned to one of two groups in a double blind clinical study. Ten were placed on tetracycline 250 mg, 6 times per day for 5 days. The other ten were given an identical appearing placebo 6 times per day for 5 days. The capsules were placed in a brown envelope so that neither the patient nor the periodontist knew which medication was being administered. The patients were randomly assigned to one of the two groups and were evaluated subjectively and objectively on the 3rd day and the 7th day. Statistically there were no differences between the two groups. In both groups there was some inflammation on the 3rd day but on the 7th day, it had subsided. Tetracycline is not recommended for routine prophylactic use in periodontal surgery.

Clinical Trials as Topic↗
PubMed1976

Diseases of the oral mucosa.

Lesions of the oral mucosa are numerous. The purpose of this article is to review the more common and most serious of them, to explore some basic-science aspects of their development and to discuss prevention and treatment.

Adult↗
PubMed1976

A comparative study of ultrasonic generators and hand instruments.

A 6-month study project utilized four human subjects and a total of 63 biopsies which were obtained from gingiva treated by hand scaling, Alpha-Sonic scaling and Cavitron. These were compared with controls (untreated specimens). Microsections of soft tissues taken immediately and after 1 and 2 weeks were evaluated. The clinical acceptability of Alpha-Sonic as a working tool for periodontal scaling is to be noted.

Dental Instruments↗
PubMed1976

Clinical evaluation of a newly designed contoured tooth-brush.

A newly designed contoured toothbrush was tested against the Oral B toothbrush in a single blind crossover study over a 6-month period using 78 patients. The findings were: (1) The contoured toothbrush was significantly better (P less than 0.01) than the Oral B brush for gingival index scores; (2) Plaque scores were lower for the contoured brush (P = 0.10); (3) No significant differences were observed with respect to calculus scores.

Dental Calculus↗
PubMed1976

Osseous autografts. III. Comparison of osseous coagulum-bone blend implants with open curetage.

A clinical investigation was undertaken to compare regeneration of osseous defects following either osseous coagulum-bone blend grafts or open debridement procedures. Seventy-five sites in 28 patients were treated by the two procedures. The average fill in the 37 intraosseous defects treated by graft procedures (initial average depth = 4.22 mm, S.D. 1.73) was 2.98 mm, S.D. 1.44. The average fill in the 38 intraosseous lesions treated by open debridement procedure (initial average depth = 3.03 mm, S.D.0.80) was 0.66 mm, S.D. 0.80. Statistical analysis showed a significant difference (P greater than 0.01) in fill patterns between the bone blend and open debridement responses in favor of graft treated sites. Therefore greater levels of osseous regeneration apparently took place in our cases following osseous coagulum-bone blend autogenous graft procedures than following open debridement procedures in all types of defects studies.

Adult↗
PubMed1975

Osseous autografts. II. Histological responses to osseous coagulum-bone blend grafts.

Three human intraosseous lesions were treated using osseous coagulum-bone blend as graft material. These sites were surgically removed 6 to 13 weeks after treatment and the blocks prepared for histologic analysis. Periodontal remodeling at the site of grafting was noted in all specimens. This remodeling involved the osseous walls, periodontal ligament, cementum and graft spicules. Both osteoclastic and osteoblastic activities were seen at the borders of the spicules. Exfoliation of spicules was particularly frequent in the six-week specimen. Nevertheless, regenerating of both bone and cementum was actively taking place even in this early specimen and was still evident in the older specimens. Of particular interest was the apparent marked increase in cementogenesis at the graft sites and the variations in parallel or functional orientation of the periodontal ligament in these areas. Significant functional orientation of segments of the periodontal ligament were seenin the early specimens, but not in the latter one. The reason for such variations in ligament pattern is not known at this time.

Adult↗
PubMed1975

Osseous autografts. I. Clinical responses to bone blend or hip marrow grafts.

A clinical evaluation was undertaken to compare regeneration of osseous defects following implantation of either osseous coagulum-bone blend from intraoral sources or autogenous iliac marrow-cancellous bone. Thirty-two transplants were performed in 15 male patients. The intraosseous defects in which marrow was placed (initial average depth = 7.18 mm) filled 60.7% (average fill = 4.36 mm). Defects in which osseous coagulum-bone blend was placed (initial average depth 4.0 mm) filled 73% (average fill = 2.93 mm). The difference in results between the two materials was not statistically significant. Therefore, similar levels of osseous regeneration apparently took place regardless of graft material used.

Adult↗