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Biomedical subjects

I V Maev

Publications and source records attributed to I V Maev.

At least 91 records · Page 5Linked to original sources
PubMed1991

[Pulmonary hemodynamics in patients with hypertension during acute drug tests using obsidan and corinfar].

Two-dimensional and Doppler echocardiographies were used to examine 102 hypertensive patients who were found to have pulmonary hypertension, whose manifestation was determined by the degree of arterial hypertension, cardiac contractile insufficiency and diminished left heart pump function. The degree of pulmonary hypertension was related to the hemodynamic type and maximal with hypokinetic circulation when the pump function of the heart was minimal. Obsidan caused a decrease in pulmonary and systemic arterial hypertension, producing higher effects with hypokinetic hemodynamics. Corinfar was demonstrated to attenuate pulmonary hypertension to a greater extent. Its action on systemic arterial hypertension was highest in patients with hyperkinetic circulation. Heterodirectional hemodynamic effects of these drugs make it expedient to study their combined action on the hemodynamic of hypertensive patients.

Adult↗
PubMed1991

[Drug therapy of pulmonary and portal hypertension in liver cirrhosis].

Detailed examination of hemodynamics in patients with portal and pulmonary hypertension was performed upon acute drug tests and course administration of nitrosorbide++, corinfar and propranolol. Ultrasound and rheography investigations were employed to elucidate the relations between portal and pulmonary hypertension in cirrhosis patients. Criteria of early diagnosis are discussed. Nitrosorbide++ produced positive effect on hepatic blood flow, corinfar improved pulmonary hemodynamics in lack of its influence on hepatic blood flow, while propranolol resulted in the drop of both portal and pulmonary hypertension, normalization of general hemodynamics.

Adult↗
PubMed1991

[Hemodynamics of the lesser circulation in patients with ischemic heart disease during acute obsidan test].

During acute obsidan testing, the hemodynamics was evaluated in the pulmonary circuit and right heart cavities of 60 patients with Functional Classes III-IV exertional angina pectoris, by using two-dimensional and Doppler echocardiographies of the pulmonary artery. According to the left ventricular myocardial volume/mass ratio, the patients were divided into 3 morphofunctional types of coronary heart disease (CHD). All the patients were found to have diminished contractility and pump function in the left heart along with moderately elevated blood pressure in the left heart and compensatory hyperfunction in the right heart, which are largely evident in the hypertrophic morphofunctional type of CHD. The degree of pulmonary hypertension was related to the severity of left ventricular dysfunction, whereas in the dilated type it was associated with its contractile disorders. In patients with the dilated and mixed types of CHD, obsidan caused a marked decrease in pulmonary hypertension, while in those with hypertrophic CHD it promoted its slight increase.

Adolescent↗
PubMed1991

[Liver function in biliary tract dyskinesia].

The authors analyze data obtained in a complex clinico-instrumental study of the functional activity of the liver, portal and hepatic blood flow in 77 patients with different forms of dyskinesias of the biliary tract. Obtained data evidence in these patients development (against the background of cholestasis) functional insufficiency of the liver and involvement of its parenchyma associated with a moderate pressure increase in the portal vein, reduction of the hepatic blood flow intensity, increase of its lability that may be a proof of development (in patients with functional bile secretion disorders) of chronic diffuse inflammatory process in the liver with subsequent appearance of clinically clear portal hypertension.

Adolescent↗
PubMed1990

[The hemodynamics of the lesser circulation in liver diseases].

The authors analyze data obtained in complex clinico-instrumental examination of the state of hemodynamic of the right compartments of the heart in 45 patients with chronic portal hypertension 20 patients with liver cirrhosis using two-dimensional echocardiography. The right ventricle and right atrium were located from the apical position of the gauge in the 4-chamber projection of the heart. Compared were values of areas of heart chambers and rate characteristics of movements of their walls and cusps of the pulmonary artery. Simultaneously ultrasonometry [correction of ultrasensometry] of the venous vessels of the abdominal cavity, liver and spleen was carried out. Signs of portal and pulmonary hypertension, loads on the right heart compartments were found in these two diseases that were more pronounced in patients with liver cirrhosis.

Abdomen↗
PubMedDate not supplied

[The effect of nitrosorbide, korinfar and obzidan on the hemodynamics of patients with chronic hepatitis and liver cirrhosis based on the data acute drug trials].

The data obtained during the complex clinical and instrumental investigation of the hemodynamics in patients with the syndrome of portal and pulmonary hypertension against the background of acute drug tests with nitrosorbide, corinfar and obsidan, are presented. By using modern ultrasound and rheographic techniques, the degree and the relationship of portal and pulmonary hypertensions in patients with chronic hepatitis and cirrhosis of the liver are evaluated, the criteria of their early diagnosis are characterized. There was shown a positive action on the renal blood flow of nitrosorbide, an improvement of the pulmonary hemodynamics in patients with diseases of the liver against the background of corinfar exerting no influence on the hepatic blood flow. Obsidan induced a significant decrease of both portal and pulmonary hypertensions, normalization of the total hemodynamics thereby producing the greatest positive effect.

Adolescent↗
PubMedDate not supplied

[A comparative evaluation of the hemodynamic effects of nitrosorbide, korinfar, obzidan and spesikor in blockade of the left branch of the bundle of His].

The paper deals with hemodynamic parameters in the greater and lesser circulations in patients with CHD concurrent with left bundle branch block. Based on the results of clinical and instrumental studies involving electrocardiography, phonocardiography and echocardiographic techniques, the authors provide early objective measures for diagnosing the hemodynamic changes occurred with development of left bundle branch block. The authors make a comparative assessment of hemodynamic effects produced by single administration of nitrosorbide, corinfar, obsidan, and spesicor in the patients examined. Nitrosorbide and corinfar improve left ventricular contractility, reduce the degree of pulmonary hypertension and right cardiac overload, while obsidan and spesicor aggravate the hemodynamic changes in patients who have CHD and left bundle branch block.

Adult↗
PubMedDate not supplied

[The use of nitrates and slow calcium channel blockers in the treatment of patients with ischemic heart disease and disorders of intraventricular conduction].

Data are submitted on the condition of haemodynamics of greater and lesser circulation in patients with ischemic heart disease (IHD) presenting with the bundle-branch block. On the basis of the results from a combined clinical-instrumental investigation involving electro- and echocardiography the authors present the early objective quantitative criteria for the diagnosis of those haemodynamic shifts occurring in formation of the bundle-branch block. The blockade of the left bundle of His has a more pronounced effect on the greater circulation haemodynamics while that of the right one--on the lesser circulation. The authors give a comparative assessment of haemodynamic effects of a single dose of isosorbide dindtrate and nifedinin in the patients. Nitrosorbide and corinfar improve contractility of the left ventricle, decrease pulmonary hypertension and overloading of the right side of the heart.

Adult↗