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Biomedical subjects

I V Maev

Publications and source records attributed to I V Maev.

At least 55 records · Page 3Linked to original sources

[Psychosomatic aspects of gastrointestinal diseases].

The article covers up-to-date information about the incidence of psychosomatic pathology among patients of gastroenterologic profile including patients with gastroesophageal reflux disease and syndrome of irritable colon. From the point of view of psychosomatic idea the article considers the factors predisposing, permitting and retarding the development of the disease. A detailed description is available in psychosomatic disturbances, modern concepts about their pathogenesis including a break of correlation between limbic and frontal regions of central nervous system and disorder in serotonin metabolism--clinical manifestations, methods of diagnosis and treatment including selective inhibitors and stimulators of serotonin reuptake and neuroleptics.

Antidepressive Agents↗

[Efficiency of quamatel in combination with device sound stimulation of the gastroduodenal zone in ulcer patients].

24-hour monitoring of gastric juice pH and esophagogastroduodenoscopy with biopsy and test for H. pylori (HP) were conducted in 117 patients with ulcer before and after treatment with famotidine (quamatel, Hungary) and device sound stimulation (DSS). Combined eradication therapy (quamatel 40 mg/day, metronidazole 500 mg 4 times a day, amoxicilline 750 mg 3 times a day, DSS) eradicated HP in 100% of patients with gastric ulcer and 91.7% of patients with duodenal ulcer. Scarring of the ulcer defect occurred for 11.8 +/- 1.1 and 15.3 +/- 1.4 days, respectively. These results are better than those of monotherapy with quamatel or DSS.

Acoustic Stimulation↗

[Use of ednit in the treatment of portal hypertension in patients with chronic hepatitis and liver cirrhosis].

AIM: To study ednit (ACE inhibitor) effectiveness in the treatment of portal hypertension in patients with chronic hepatitis (CH) and hepatic cirrhosis (HC). MATERIAL AND METHODS: The examination of 87 patients with active CH and 54 patients with HC at the preascytic stage included two-dimentional ultrasonic scanning of the abdominal organs with doppler fluometry of the vessels in the territory of the portal vein, tetrapolar rheohepatography, ultrasound investigation, angiography of the abdominal vessels. The patients received combined therapy with ednit in a dose 5 mg twice a day for at least 5 weeks. RESULTS: Patients with active CH and HC having portal hypertension treated with adjuvant ednit in the above dose achieved marked clinicobiochemical remission quicker, portal-hepatic circulation improved. CONCLUSION: The addition of ednit to therapy of active CH and HC with portal hypertension is effective as it lowers total peripheral vascular resistance which eventually results in a fall of pressure in the territory of the portal vein and improvement of hepatic circulation. The highest effect is reached in administration of 5 mg twice for 24 hours.

Adolescent↗

[24-hour monitoring of gastric juice pH in assessment of anti-ulcer treatment].

AIM: Comparison of various schemes of three-component eradication of duodenal ulcer (DU) using 24-h monitoring of gastric juice pH. MATERIALS AND METHODS: 62 DU patients in aggravation period have undergone 24-h monitoring of gastric juice pH and esophagogastroduodenoscopy with biopsy and H.pylori test of the treatment beginning and end. Patients of group 1 (n = 28) received ranitidin, metronidazole and amoxicillin while patients of group 2 (n = 34) took quamatel, metronidazole and amoxicillin. RESULTS: 24-h monitoring of pH of the gastric juice demonstrated that three-component therapy consisting of quamatel (20 mg/day, metronidazole (500 mg 4 times a day), amoxicillin (750 mg 3 times a day) maintains the level of intragastric acidity optimal for quick scarring of duodenal ulcer defect and led to eradication of H.pylori in 91.2% of cases. CONCLUSION: 24-h monitoring of gastric juice pH is a significant method of assessment of antiulcer treatment efficacy.

Adult↗

[Josamycin combination with ranitidine in therapy of gastroduodenal ulcer: clinical efficiency].

Efficacy of a novel eradication treatment with ranitidine, trichopol and jozamycin was compared to that of the standard three-component therapy and monotherapy with ranitidine in 76 patients with exacerbation of gastric and duodenal ulcer. Therapeutic monitoring of ranitidine was performed. In relation to healing of ulcer defect and eradication of Helicobacter pylori, jozamycin is not less effective and more safe than standard three-component therapy. Interaction of the scheme components increases plasma concentration of ranitidine especially in patients with concomitant hepatic and renal diseases.

Adult↗

[Motor and secretion function of stomach and duodenum, duodenogastric reflux in patients with duodenal ulcer].

Gastric secretion, motor function and tonicity of the stomach and duodenum, duodenogastric reflux were studied in inpatients with two clinicopathogenetic types of duodenal ulcer: observed at young age (type 1) and in later life (type 2). The examination included pH-metry with simultaneous balloon cimography, chromogastroduodenoscopy with Kongo-red, tests for Helicobacter pylori conducted on the biopsy samples. All the patients were found to have continuous acid production. High acid production was more frequently registered in males with the disease type 1, the lowest production was in females with the disease type 2. Duration of the acid inflow into the duodenum in patients with the disease type 2 was greater than that in young subjects. Mild ulcer was associated with moderate acidity in the duodenum, in severe ulcer the acidity was very high. Males with the disease 1 and 2 and females with type 2 had hyperkinetic, hypertonic gastric motor function. In duodenal ulcer prevalent is hypertonic, hyperkinetic type of duodenal motor function being most frequent among males with the disease type 2. Duodenogastric reflux occurs more often in patients with intensive acid production associated with hypotonic, hypokinetic motor type and duodenal tone.

Adult↗

[Clinical features of gastrointestinal diseases in patients with primary mitral prolapse].

Whether patients with mitral prolapse (MP) have specific features in the course of their gastrointestinal diseases (GD) was studied in 420 MP patients with various GD. Echocardiography and examination of the vegetative status were conducted in all the patients. On demand, esophagogastroduodenoscopy, ultrasonic investigation of the abdominal organs, multistage fraction duodenal intubation were made. The findings evidence of more severe course of GD in MP patients. This manifests in early onset, severe pain and dispeptic syndromes, marked mucosal inflammation and is explained by dysfunction of the vegetative nervous system and generalized dysplasia of the connective tissue.

Adult↗

[Central hemodynamics and portal-hepatic blood flow in patients with acute and chronic virus hepatitis].

AIM: To characterize central hemodynamics and portal-hepatic blood flow in patients with acute and chronic viral hepatitis. MATERIAL AND METHODS: Ultrasound investigation, tetrapolar rheography, hepatic scintigraphy were made in 149 patients with acute and chronic viral hepatitis B, C and B + C. RESULTS: The above patients had disturbances in central hemodynamics manifesting with developing myocardiodystrophy and hyperkinetic hemodynamics syndrome; decreased intensity and increased amplitude of respiratory fluctuations of volumic hepatic blood flow; impairment of peripheral blood flow. CONCLUSION: The above changes were most prominent in patients with chronic hepatitis B + C.

Acute Disease↗

[The role of different investigations in diagnosis of functional disorders of the biliary system].

The paper presents the results obtained upon examination of inpatients with various types of biliary dyskinesia. The examination included: fraction chromatic duodenal intubation, stepwise manometry, cholecystography, ultrasound investigation of the liver, gall bladder, biochemical tests of the bile. Fraction duodenal intubation discovered gall bladder dysfunction. The manometry was necessary for diagnosis of duodenal hypertension. X-ray revealed primary defects in gall bladder motility. It is concluded that the diagnosis of functional disorders implies combined clinical and instrumental modalities.

Adolescent↗

[The correction of the hemodynamic disorders in patients with IHD complicated by intraventricular blocks by using beta-adrenergic agents].

Basing on ECG findings, the authors compare hemodynamic effects of a single dose of isadrin, obsidan and spesicor in patients with coronary heart disease complicated by bundle-branch block. Isadrin improves left ventricular contractility, reduces pulmonary hypertension and right heart overload. Obsidan and spesicor aggravate the existing hemodynamic disorders in the above patients.

Adrenergic beta-Agonists↗

[Evaluation of pulmonary hypertension by dopplerography in patients with nonspecific pulmonary diseases].

Doppler echocardiography was used to quantify pulmonary hypertension and phase pattern of right heart systole in 140 patients with nonspecific pulmonary diseases to study hemodynamic characteristics of pulmonary circulation and right heart as well as external respiration. There appeared a relationship between the severity of pulmonary hypertension, bronchial obstruction and arterial hypoxemia. It seems that in nonspecific pulmonary diseases hemodynamic changes arise prior to functional disorders of external respiration.

Adolescent↗

[Characteristics of external respiration function and pulmonary circulation in patients with ischemic heart disease complicated by disorders of intraventricular conduction].

The authors provide evidence on the condition of external respiration and hemodynamic shifts in the lesser and greater circulation in coronary patients with bundle-branch block; establish early objective quantitative criteria of the diagnosis of hemodynamic impairment arising in formation of the above blocks basing on ECG, phonocardiography, echocardiography findings; compare hemodynamic effects of single-dose nitrosorbide and corinfar in the above patients. Nitrosorbide and corinfar correct hemodynamics and external respiration, the former being more effective in normalizing the greater, while corinfar the lesser circulation.

Adult↗