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Biomedical subjects

I Tomov

Publications and source records attributed to I Tomov.

At least 37 records · Page 2Linked to original sources
PubMed1986

[Hemodynamic indices assessed by impedance cardiography in patients with the subacute stage of myocardial infarct before and during bicycle ergometry].

The hemodynamic indices were determined in 51 patients with myocardial infarction, subacute stage, before and after bicycle ergometric loading. The following indices were determined by impedance cardiography: cardiac output, total peripheral resistance, volume velocity of blood ejection, power of cardiac contractions, index of myocardial contractility etc. The results reveal that the patients with subacute stage of myocardial infarction have reduced reserve possibility of blood circulation apparatus. Signs of latent cardiac failure are manifested in case of extensive localization with transmural involvement, because of seven disorders in the contractile function of myocardium. The adaptation to physical loading, in the rest of the patients, is better but still far less than that in healthy subjects.

Adult↗
PubMed1986

[Plasma volume changes in essential hypertension patients].

Plasma volume, cardiac output, velocity of blood flow and total peripheral vascular resistance were studied in 180 patients with essential hypertension, stages I, II and III according to WHO classification. Increased plasma volume was established in the majority of the patients with early stage of the disease and in 36 per cent of the patients with advanced essential hypertension. The studies reveal that the changes in plasma volume are of importance for the deviations of the other hemodynamic indices and for the reorganization of the hemodynamics in the patients with essential hypertension.

Adult↗
PubMed1986

[Preoperative clinical and hemodynamic assessment of patients for surgical revascularization of the myocardium].

A group of 35 patients with ischemic heart disease (IHD) and 6 patients with aquired heart defects, with established significant coronary obstruction were studied. The clinical picture of the patients with IHD is dominated by severe, refractory to treatment angina pectoris with extensive and high-degree stenosing coronary angina pectoris in combination with a relatively preserved left ventricular function. The patients with aquired defects have no anginal complaints. The aortic-coronary by-pass is justified in the light of the modern studies in the world. The necessity of rapid advancement of coronary surgery in Bulgaria is underlined.

Angina Pectoris↗
PubMed1985

[Computer calculation of echocardiographic indices].

The objective of the study was to determine the degree of discrepancy in the data from echocardiographic indices, determined by the original Bulgarian apparatus "Echocomputer" (engineer Daskalov) and by two independently working researchers as well as the accuracy of repetition by one researcher. M-echocardiographic records were used for that purpose of 22 patients with various cardiopathies, the indices determined by the computer were compared with the data of the same indices but obtained by calculations according to the well known classical formulae. Two statistical methods were used--variation and correlation analysis. No statistically significant difference was established between the compared values of Echocomputer and considerable correlation dependence in the comparison of the data from two different ways of calculation of EchoCG-indices.

Computers↗
PubMed1985

[Combined acute myocardial infarct and pulmonary thromboembolism with fatal outcome].

A retrospective clinical and pathologicoanatomic analysis was made of 37 patients with the combination of acute myocardial infarction (AMI) and pulmonary thromboembolism (PTE), that had a lethal end. The following facts were established: The combination of AMI with PTE is established in 7.89% in AMI. All patients have several preconditioning factors for PTE, advanced age including. PTE advances usually in extensive anterior and anterior-posterior myocardial infarction, complicated with cardiac insufficiency. In rare cases, a reverse succession is likely--massive PTE with a following, most frequently posterior-inferior AMI. The percentage of the undistinguished PTE in case of AMI is high--46%. The diagnosis of PTE in AMI is made, with a high probability, in acutely advancing respiratory distress, tachycardia (tachyarrhythmia, pulmonary hypertension, loading of right ventricle, arterial hypotension, phlebothrombosis in the absence of data for extension of the myocardial infarction. ECG, roentgenography, laboratory investigations do not essentially improve the possibilities of making the diagnosis of PTE in AMI.

Aged↗
PubMed1985

[Clinical and echocardiographic symptoms of mitral valve rupture].

The diagnostic sensitivity, specificity and predicting accuracy of the various alterations, established by one-dimensional echocardiography (M-EchoC) were determined in 23 patients with rupture of mitral chordae. The diagnosis of mitral insufficiency, resulting from chordal rupture was confirmed at operation, with angiocardiography and/or bi-dimensional echocardiography. Almost all MEchoC alterations were with a relatively low sensitivity (10-50%), high specificity (60-100%) and moderately high predicting accuracy (50-80%). Of more essential diagnostic significance--moderate sensitivity and high specificity with high predictive accuracy, are the following alterations: systolic fibrillation of mitral valve, diastolic fibrillation of mitral valvular cusps, paradoxical (chaotic) movement of posterior mitral cusp during diastole. Very little sensitivity (10%) but with high specificity (100%) was established in pathological systolic echoes in the cavity of left auricle. In the majority of the cases, the rupture of mitral chordae induced grave mitral regurgitation, conditioning the various stages of cardiac insufficiency. Relatively rare is the light to moderately grave mitral regurgitation with stable hemodynamics and preserved functional capacity.

Adult↗
PubMed1985

[Relaxation and filling of the left ventricle measured by computer analysis of the unidimensional (M-type) echocardiogram in healthy subjects and patients with hypertrophic cardiomyopathy].

The indices of systolic and earli diastolic function (relaxation and rapid filling) were established in 16 healthy subjects and 35 patients with idiopathic hypertrophic cardiomyopathy by computer analysis ("Echocomputer" RIEMT--MA, Sofia) and left ventricular and mitral valve M-type echocardiogram. In a considerable part of the partients with hypertrophic cardiomyopathy, pathological changes were established in the diastolic function of left ventricle--lengthening of iso-voluminal relaxition, reduction of velocity and increase of the dimension of left ventricular cavity, reduction of velocity and fraction of blood flow in the phase of rapid filling of left ventricle. Those changes of diastolic function are a manifestation of increased resistance, restriction of left ventricular filling that could partially explain the tendency to reduction of stroke and minute volume in some patients with hypertrophic cardiomyopathy with normal and increased indices of systolic function of left ventricle (fraction of shortening, ejection fraction, veloycity of reduction of dimension of left ventricle in the phase of ejection)? There is considerable correlation between the changes of diastolic function and those of the hypetrophic process and reduction of left ventricular cavity. The computer analysis of the echogram, enables the more detailed, fast and accurate determination of important indices of diastolic and systolic function of left ventricle, with a good repeated reproducibility.

Adult↗
PubMed1985

Clinical and echocardiographic characteristic of mitral valve chordae rupture.

In 23 patients with mitral valve chordae rupture, the diagnostic sensitivity, specificity and predictive accuracy of various changes found by one-dimensional echocardiography (M-echo) were determined. Nearly all M-echo changes have a relatively low sensitivity (10-50%), high specificity (80-100%) and moderate predictive accuracy (30-80%). Greater diagnostic value--moderate sensitivity, high specificity and greater predictive accuracy--is shown by the following changes: systolic mitral valve flutter, diastolic mitral leaflets flutter, paradoxical (chaotic) movement of the posterior mitral leaflet in diastole. Of very low sensitivity (10%) but high specificity (100%) are pathological systolic echo-signals in the left atrial cavity.

Adolescent↗
PubMed1983

[Effect of the use of lidocaine on patients with acute myocardial infarct].

In 411 patients with acute myocardial infarction (AMI) the effect of intravenous lidocaineeee administration was studied in a suboptimal dose - under 1,5 mg/min (to 1979) and in the optimal dose - over 1,5 mg/min, minimum 2 mg/min during the first 12 hours, with an average 24 h dose, 3,0 g in the course of 48 hours. The patients were grouped into three prognostic groups, depending on their initial assessment according to the coronaryprognostic index of M. R. Norris (1969). The indices, via which the drug effect was determined; were 13, the more significant ones beind: ventricular arrhythmias, early lethality rate, postinfarction angina pectoris and regression fo lesion-ischemic ST-T alterations. It was established, after the analysis of the data obtained, that the prophylactic and therapeutic use of lidocain, considerably reduced the incidence of ventricular arrhythmias in patients with AMI. Lidocain, in an optimal dose, reduces the incidence, justifying its routine administration. Lidocain effect on ventricular arrhythmias, the early lethality rate and certain complications (postinfarction angina pectoris, early cardiac insufficiency, regression of ST-T alterations) in AMI, depend on the initial prognosis and the stage of the hemodynamic disorders.

Adult↗
PubMed1983

[Diastolic and systolic functions of the left ventricle determined by M-echocardiography in idiopathic hypertrophic cardiomyopathy].

The diastolic function and the correlation between pump and diastolic function of left ventricle were studied in 35 patients with idiopathic hypertrophic cardiomyopathy with subaortic stenosis via a M-echocardiographic investigation by Echoview 80 C in the routine method. The following indices were used: A. For the diastolic function: 1. Telediastolic dimension (TDD) and volume (TDV) of left ventricular cavity. 2. Dimension (DPhFF) and volume (VPhFF) of the left ventricular cavity at the end of the phase of fast filling; 3. Velocity of fast filling of the left ventricle (ml/sec) - (formula; see text) 4. Fraction of fast filling of left ventricle (%) - (formula; see text) 5. Velocity of backward motion of the anterior mitral cusp at the beginning of diastole (E - F segment); 6. Velocity of early diastolic motion of the posterior wall of left ventricle (PWLV); 7. Ratio between early diastolic (D) and systolic (S) interval of PWLV: D/S; 8. Telediastolic interval (A - C) of mitral valve; 9. Index of fast emptying of left ventricle; 10. Amplitude E - E' of mitral echogram; II. Area (cm2) between two mitral cusps in diastole. B. For the systolic (pump) function: 1. Stroke and minute volume (SV, MV) of left ventricle according to the cubic formula and Teicholz formula; 2. Telesystolic dimension (TSD) and volume (TSV) of left ventricular cavity; 3. Fraction of shortening (FS) of left ventricle (%); 4. Mean velocity of shortening of the circumferential fibres (mVcf) of left ventricle (circumf./S); 5. Ejection fraction (EF) of left ventricle (%). 6. Distance between left ventricular endocardium of interventricular septum and point E of mitral valve; 7. Fraction of systolic thickening of IVS and PWLV; 8. Velocity of systolic thickening of IVS and PWLV; 9. Amplitude of systolic motion of IVS and PWLV.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗