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Biomedical subjects

I Steiner

Publications and source records attributed to I Steiner.

At least 181 records · Page 10Linked to original sources

[Multiple endocrine neoplasia syndrome type I - familial occurrence].

Endocrine adenomatosis of Langerhan's islets (gastrinoma), parathyroid, pituitary gland and adrenals manifested itself at a proband by Zollinger-Ellison syndrome and perhaps hyperparathyroidism. Proband late brother's autopsy was reviewed and a similar morphology was found with Cushing's syndrome and peptic ulcer. Both brethren's mother died from a complication of recurring peptic ulcer.

Adolescent↗

[Heart rupture in acute myocardial infarct--analysis of 110 cases].

One hundred and ten cases of heart rupture (27%) were found among 408 postmortems of acute myocardial infarction from 1976 to 1982. After intensive care units were introduced the rate of rupture increased from 17% to 30% and reached 39% of the total. Ruptures were more frequent in women (32%) than in men (24%), their frequency increasing with the age; average age was 70 years in men and 72 years in women. Sudden death occurred in 16% of the patients; the interval between the first symptoms of infarction and death was 24 hours in 39% and 1 week or less in 90% of those affected. Most cases with extremely short history showed a fully developed infarction at autopsy. The rupture was, in fact, the first manifestation of latent ("silent") infarction. Less usual types of heart rupture (incomplete rupture, i. e. dissection of the free wall of the left ventricle and rupture of interventricular septum or papillary muscles of the left ventricle) are discussed in detail. Practical experience of the study is summarized in comments on heart autopsy.

Aged↗

[Pseudoaneurysm of the left ventricle (healing of the cardiac wall rupture in a myocardial infarct)].

Rupture of the left ventricle in an infarction is nearly always ensued by a massive pericardiac haemorrhage and sudden death of cardiac tamponade. Quite exceptionally, haemorrhage can be confined in pericardiac adhesions which is followed by a pseudoaneurysm. Case of a 62 year old man is depicted who deceased suddenly 7 months after an acute posterior wall heart infarction. A voluminous pseudoaneurysm was found at the ruptured posterior wall of the left ventricle. Retrospective clinical evaluation fixed the heart rupture on the 10th day after infarction.

Heart Aneurysm↗

[Mycotic esophagitis - a contribution to its etiology].

Six cases of mycotic pseudomembrane inflammation of the esophagus formed 0.6% of all the necropsies within observed period. The basic disease was malignant tumour in 5 patients, non-tumorous blood disease in one. Culturally, yeast-like organisms of the genus Candida were proved in all cases. In three cases necrotizing and pseudomembrane inflammation of the larynx developed simultaneously. In the control group cultivation examination of the esophagus and larynx was made in 50 "at risk" patients (children, diabetics and oncologic patients) without any overt mycotic disease. A positive mycologic findings was from the esophagus in 60% from the larynx in 38%. In both localities the most frequent was Candida albicans, in isolated cases also conditionally pathogenic fungi of the genera, Saccharomyces and Torulopsis were detected. All these organisms apparently may spread from the digestive tract to the upper respiratory passages.

Adult↗

Spontaneous calcific coronary embolisation: necropsy x-ray study.

Thirty-one hearts with advanced calcification of one or both left heart valves were investigated for the presence of spontaneous calcific emboli. X-ray (Mammograf) showed coronary emboli in 14 cases, that is, in 45% of the whole series. In seven cases (23%) calcific particles were also present in the left ventricular cavity. A total of 265 calcific emboli (205 intracoronary plus 60 intravenous) was demonstrated. The embolisation occurred most frequently and most extensively in association with postrheumatic mitral valve disease. Coronary calcific embolisation must be considered in the differential diagnosis of symptoms of ischaemic heart disease in patients suffering from valvular heart lesions.

Adult↗

[Ebstein's anomaly of the heart with ventricular septal defect at age 65].

A postmortem in a woman of 65 revealed Ebstein's anomaly of the heart with ventricular septum defect. The defect had been closed from the right side by the septal cups of the tricuspid valve coalescing with its edges. Literary sources refer to only 6 cases of Ebstein's anomaly in subjects older than our patient. The simultaneous presence of spontaneously closed defect of ventricular septum makes it an entirely exceptional case.

Aged↗