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Biomedical subjects

I Segal

Publications and source records attributed to I Segal.

At least 199 records · Page 11Linked to original sources
PubMed1977

The giant duodenal ulcer syndrome.

Thirteen patients with giant duodenal ulcer manifested with a distinct clinical syndrome. The condition has a characteristic clinical, radiological and endoscopic presentation. It is associated with a high mortality when treated medically, and constitutes a definite indication for surgery. The giant duodenal ulcer forms a high proportion of duodenal ulcers in a recently urbanized Black community, and may be one of the dramatic and significant presentations of this disease in the developing countries.

Adolescent↗
PubMed1977

Cavernous haemangioma of the spleen. A case report.

Splenic cavernous haemangioma is a rare cause of splenomegaly. It is a benign tumour which has seldom been diagnosed pre-operatively, because the clinical presentation is usually atypical. This is reflected in a patient who presented with splenomegaly, and in whom cavernous haemangioma of the spleen was diagnosed only after operation.

Diagnosis, Differential↗
PubMed1977

Emergence of diverticular disease in the urban South African black.

A low residue, fiber-deficient diet has been postulated as the cause of diverticular disease--the commonest affliction of the colon in the Western nations. This condition is virtually unknown in Africans (blacks) who live south of the Sahara, and who have not changed their traditional high residue diet. This paper presents 16 Africans with diverticular disease. A disturbing feature is that 5 of the patients are young, being in their fourth decade, and only 4 are over the age of 60. Their dietary history confirms the hypothesis as to the etiology, and also shows that the urbanization of the South African black has been accompanied by the emergence of diverticular disease, a condition higherto virtually nonexistent in this population.

Adult↗
PubMed1975

The irritable bowel syndrome in the urban South African Negro.

The 'irritable bowel syndrome' is a disorder of civilisation, in which a low-residue fibre-deficient diet is probably the major aetiological factor. This is illustrated by the first 2 Black patients presenting with this syndrome. They represent a population which has only recently changed from a rural to an urban way of life.

Adult↗
PubMed1975

Tuberculous osteomyelitis of the rib. A case report.

Tuberculous osteomyelitis of the ribs is a rare condition. This report describes a circumscribed tuberculous lesion of the rib shaft which presented as an abscess of the chest wall. The management is described and the literature is briefly reviewed.

Abscess↗
PubMed1973

Evolution of diabetes mellitus in a case of Friedreich's ataxia.

A 12 year old girl with Friedreich's ataxia, in whom progression from chemical to severe insulin-dependent diabetes mellitus occurred over a two year period, is presented. During the phase of subclinical diabetes her plasma immunoreactive insulin response to oral glucose was markedly increased, but when she became symptomatic gross insulin deficiency had supervened. This report draws attention to the unusual disorders of carbohydrate metabolism and insulin secretion that may occur in a variety of neurological conditions.

Blood Glucose↗
PubMedDate not supplied

Can the risk of colon cancer be lessened?

Colon cancer was rare or uncommon in the past, and still is in traditionally-living third world populations. It now affects 3-5% of western populations. Epidemiological, case control, experimental and other studies suggest that proneness to colon cancer can be lessened by major dietary changes, principally decreasing fat intake by a third, and doubling the intake of fiber-containing foods, especially vegetables and fruit--recommendations similarly advocated for the avoidance of coronary heart disease and other degenerative diseases. Among nondietary factors, evidence indicates familiality, obesity and atmospheric pollution to be contributory, while parity, physical activity, solar radiation, high social class, estrogen use, and aspirin use, appear protective. Despite insufficiencies of knowledge of prevention, avoiding action should certainly be taken by those familially prone. For the rest, conceivably a prudent life-style could benefit a proportion avoiding colon cancer.

Aged↗
PubMedDate not supplied

Management options for pancreatic pseudocysts.

Between July 1987 and February 1990, 42 patients with pancreatic pseudocysts were treated. In 83% the pseudocyst was related to alcohol. Patients were managed by observation (7), surgical external drainage (7), and internal drainage (12). Fifteen patients were treated by ultrasound guided percutaneous catheter drainage (UGPCD) with apparent success in 67%. In 5 of these UGPCD was abandoned because of either prolonged drainage or infection of the pseudocyst. In patients with recurrent pseudocysts or in those with failed UGPCD, the cystic collections were successfully drained internally in 16 out of 17 patients (94%). Internal drainage appears to be acceptable treatment for mature pseudocysts, recurrent pseudocysts or for failed UGPCD, provided there is no downstream pancreatic duct obstruction or duct dilatation. If either exist, resection or direct ductal drainage will be required.

Adult↗
PubMedDate not supplied

Risk factors and survival from colorectal cancer in black patients in Soweto, South Africa.

In Africa, while colorectal cancer is very uncommon in the black population, it is rising in urban dwellers. A series of 42 patients treated at Baragwanath Hospital, Soweto, were compared with 92 controls. Average age of patients was relatively low 55 years. 73 per cent presented late with far advanced disease at Stages C and D. No familial component was apparent. Patient's years of schooling and social class were non-revealing compared with data on controls. Dietarily, the same applied to fat intake (relatively low) and fibre intake (considerably decreased). Median survival time was short, 7.5 months.

Adult↗
PubMedDate not supplied

Survival of black patients with gastric cancer in Soweto, Johannesburg, South Africa.

In a series of 39 black gastric cancer patients, treated at Baragwanath Hospital, Soweto, Johannesburg, the time of 50 per cent mortality was 3.5 months, half that of white patients. Patients' median age was lower than that of white patients, 58 versus 70 yr. Male/female ratio was 1.3:1. Black patients presented late; no patients' lesions were at clinical stages I and II, compared with 5-15 per cent reported for white patients. Weight loss, abdominal pain and vomiting were predominant features. Frequencies of smoking and of alcohol consumption in male and female patients appeared much the same as those prevailing in the general population. No marked differences between patients and controls were apparent in socioeconomic state, educational level, general dietary intake, nor in ownership of a refrigerator.

Black or African American↗