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Biomedical subjects

I Moseley

Publications and source records attributed to I Moseley.

At least 19 recordsLinked to original sources
PubMed1995

Assessment of the safety and efficacy of iobitridol, an iodinated contrast medium (30% iodine), in cranial CT.

In a single-centre comparative randomised double-blind trial, 40 patients undergoing head CT were examined using iobitridol and compared with 40 examined using iohexol. The contrast media were assessed for clinical safety and diagnostic efficacy. No significant difference was observed between the two groups and there were no significant reactions. It is concluded that iobitridol is a safe and effective contrast medium.

Adult↗
PubMed1995

Orbital involvement in multifocal fibrosclerosis.

Multifocal fibrosclerosis is a condition of unknown aetiology, characterised by fibrous lesions occurring at a variety of sites. Clinical variants include retroperitoneal fibrosis, Riedel's thyroiditis, sclerosing cholangitis, and mediastinal fibrosis. Orbital pseudotumour has been reported as a manifestation of this condition. Three patients with multifocal fibrosclerosis in whom orbital involvement was the dominant feature are described.

Aged↗
PubMed1992

Haemangiopericytoma of the orbit.

Orbital haemangiopericytomas are ideally managed by complete surgical excision in the first instance. This is frequently not achieved, because difficulty in making the diagnosis preoperatively results in incisional biopsy and the highly vascular nature of the tumour makes complete excision difficult. A series of 12 patients with orbital haemangiopericytoma seen over a 23-year period is presented. The following combination of clinical and radiological features is suggestive of haemangiopericytoma. 1. Painless non-axial proptosis with downward displacement of the globe. 2. Intermittent upper lid swelling. 3. A soft, superiorly located mass with poorly defined borders, especially with a blue hue. 4. A superiorly located, rounded or elongated extraconal mass on CT, isodense with brain, with smooth, well-defined borders and moderate to marked enhancement with the injection of intravenous contrast medium. 5. Significant blush in all three phases of carotid angiography, without prominent arteriovenous shunting. Once haemangiopericytoma is suspected, complete surgical excision is recommended.

Adult↗
PubMed1991

Granular cell tumour of the orbit: radiological findings.

Radiological findings in four cases of intraorbital granular cell tumour are presented, and compared with those previously reported. These rare lesions often appear to involve an extraocular muscle, and are seen on CT as an enhancing mass, usually well defined, and frequently lying anteriorly. Plain films are characteristically normal; angiographic findings range from normality to a dense tumour blush.

Adult↗
PubMed1991

Do bilateral optic nerve sheath meningiomas exist?

All patients examined at The National Hospital for Nervous Diseases, Queen Square, from 1983 to 1987 with radiological evidence of meningiomas involving both optic nerves within the orbits have been reviewed. Their clinical and X-ray computed tomography (CT) features are different from those of patients with unilateral tumours, and they appear to form a separate group, probably representing optic nerve involvement by a primarily retro-orbital meningioma.

Adolescent↗
PubMed1990

Diagnostic value of 'optic foramen views': experience from an eye hospital.

A prospective survey of 174 consecutive patients in whom plain radiographs of the optic canals were requested by ophthalmologists disclosed no cases in which these films made a positive contribution to management. It is suggested that as a general rule this radiographic examination has no useful role.

Adult↗
PubMed1988

Long term effects of the introduction of noninvasive investigations in neuroradiology. Part 2: Effects on management of individual patients.

Review of imaging investigations undergone by cohorts of in- and outpatients of a neurological hospital at 8 year intervals over a 25 year period showed that while the pattern of investigation of the individual patient was little affected by the introduction of radionuclide studies, the subsequent availability of computed tomography had a rapid and cumulative effect on the use not only of invasive investigations, but also of plain films and other noninvasive examinations.

Ambulatory Care↗
PubMed1987

Antibody to human T-lymphotropic virus type 1 in West-Indian-born UK residents with spastic paraparesis.

Of 13 West-Indian-born UK residents with spastic paraparesis of unknown cause, 11 were tested for serum antibody to human T-cell lymphotropic virus type 1 and all were positive. Their magnetic resonance imaging scans were normal or showed only minor abnormalities in the brain, and the spinal cord was normal in the 5 investigated. Of 48 patients with multiple sclerosis, mainly caucasian, none had antibody to HTLV-1 in the blood.

Adult↗
PubMed1987

Interpreting the skull X-ray.

With the introduction of other noninvasive imaging procedures, indications for X-rays of the skull have become fewer and more specific. Their correct interpretation remains important, however, to ensure not only that significant abnormalities are not overlooked, but--perhaps more importantly--that failure to recognize normality does not have adverse effects on management.

Bone Diseases↗