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Biomedical subjects

I Kamoi

Publications and source records attributed to I Kamoi.

At least 37 records · Page 2Linked to original sources
PubMed1979

[Clinical significance of serum bile acid radioimmunoassay in hepatobiliary diseases--with special reference to the CG/SLCG ratio (author's transl)].

Both serum cholylglycine (CG) and sulfolithocholylglycine (SLCG) levels were radioimmunoassayed by PEG method in 209 samples (204 hepatobiliary diseases, 5 normal controls). 1) The results revealed that serum bile acid levels were excellent indicators for hepatic dysfunction in comparison with the conventional liver function tests. 2) Means of 19.4 +/- 9.3 microgram/dl for CG and 21.7 +/- 6.7 microgram/dl for SLCG were obtained in controls. Most hepatobiliary diseases demonstrated abnormally high bile acid levels, with extremely high CG values in conditions with bile stasis. 3) To differentiate various hepatobiliary diseases more clearly, the ratio of the primary and secondary bile acids (CG/SLCG ratio) was introduced (1.0 +/- 0.6 for controls). In cases of bile stasis, CG/SLCG ratios ranged from 7.8 +/- 4.8 for intrahepatic cholestasis to 34.8 +/- 27.6 for congenital biliary atresia, while other hepatic disorders demonstrated relatively low values. We conclude that the CG/SLCG ratio is a useful index for cholestasis. Diagnosis of the congenital biliary atresia could be possible.

Biliary Tract Diseases↗
PubMed1979

[Clinical significance of urinary CEA measurement as a screening test of bladder cancer (author's transl)].

Non-infected urine samples of twenty six preoperative bladder cancers were examined by urinary CEA radioimmunoassay and exfoliative cytology. There were 65% of urinary CEA positivity and 58% of cytological positivity (class III, IV, V). CEA measurements were positive in 8 of 11 negative cytology cases (class I and II). Exfoliative cytological examination failed to detect most of well differentiated transitional cell carcinomas, while urinary CEA study detected 4 of 6 such cases. Combination of both urinary CEA measurement and cytology resulted in 85% of positivity. Therefore we recommend routine use of this combination as a screening system of bladder cancer.

Adult↗
PubMed1978

Urinary carcinoembryonic like antigen levels in patients with urinary tract reconstruction using bowels.

Urine CEA levels of sixty six cystectomy patients with urinary tract reconstruction using the small or large bowel was evaluated. Most of them had abnormally high CEA levels regardless of bladder tumor recurrence. Ileal conduit cases showed higher CEA levels than those of colocystoplasty cases. We think this is probably due to difference of mucosal surface areas rather than of original location of the resected specimens, for the small bowel contains much wider mucosal surface in a length unit.

Adolescent↗