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Biomedical subjects

I Kaffe

Publications and source records attributed to I Kaffe.

At least 37 records · Page 2Linked to original sources
PubMed1993

Extraction site healing in rats. A radiologic densitometric study.

The present study uses a simple, objective method to radiographically evaluate the changes that occur during socket healing in rats. Mandibular left first molars were extracted in 35 Wistar rats, which were then sacrificed at 0, 7, 14, 21, 28, 45, and 60 days after surgery. Mandibles were removed, placed on an ANSI size 2 film, and exposed with an aluminum step-wedge, 0.5 to 3.0 mm. Socket density was measured with a digital densitometer and related to the equivalent density of aluminum. Increased density of the image of the apical and crestal areas of the socket was observed on day 7. Maximum density was reached by day 28 in the apical area; in the crestal area, density increased at a slower rate. The density changes found in the present study agree with the known histologic reports of socket healing in rats. Densitometric evaluation of extraction socket healing, using a step-wedge with 0.5 mm increments, is a useful and reliable tool to objectively assess bone formation and mineralization.

Aluminum↗
PubMed1993

Recovery of the infraorbital nerve after zygomatic complex fractures: a preliminary study of different treatment methods.

The infraorbital nerve (ION) is often involved in trauma to the zygomatic complex (ZC), resulting in sensory disturbance of the area innervated by it. The purpose of the study was to compare the incidence of persistent sensory disturbance after recovery from isolated simple fractures of the ZC, with four treatment methods: 1) closed reduction via subcutaneous approach without fixation; 2) open reduction via subcutaneous approach without fixation; 3) open reduction via oroantral approach and support of the complex by an intraantral Foley catheter; and 4) open reduction via Gillies approach with fixation of the frontozygomatic (FZ) fracture with wire osteosynthesis, and open reduction via Gillies approach with fixation of the FZ fracture with miniplate osteosynthesis. Analysis revealed that patients treated with miniplate osteosynthesis exhibited a trend for higher recovery rate of the (ION) than with the other three methods. No significant differences were found among the other three methods.

Bone Plates↗
PubMed1993

Comparative evaluation of different radiographic projections of zygomatic complex fractures.

Diagnosis of zygomaticomaxillary fractures is a major problem in radiographic interpretation. The purpose of the present study was to evaluate several radiographic examinations performed in an emergency room to diagnose zygomatic complex (ZC) fractures, in order to determine which is the single best radiographic projection for this purpose. Radiographs of 160 patients with ZC fractures were evaluated retrospectively. The modified P-A projection (10 degrees-20 degrees) provided a clear image of the frontozygomatic, infra-orbital rim and temporozygomatic fracture lines in all cases. In half the cases, the modified P-A projection also clearly demonstrated the fracture line in the zygomatic maxillary buttress. On the other hand, the Water's view demonstrated the fracture line in the zygomatic maxillary buttress and the temporozygomatic bone in all cases, but in only 65% of the cases was the fracture line in the infra-orbital rim and the frontozygomatic bones shown. The modified P-A projection was found to be the single best radiographic examination that should be performed in the emergency room to diagnose ZC fractures.

Evaluation Studies as Topic↗
PubMed1993

Long-term effect of desalivation on extraction wound healing: a densitometric study in rats.

The study evaluates radiographically the long-term changes that occur during the healing of tooth sockets in a desalivated rat model. Experimental rats underwent sialadenectomy of the submandibular and sublingual glands and ligation of the parotid ducts. Mandibular left first molars were extracted and the rats killed at 0, 14, 21, 28, 45 and 60 days post-extraction. The mandibles were removed, cleaned of soft tissue, placed on a size 2 dental X-ray film and exposed together with an aluminium stepwedge 0.5-3.0 mm. Socket density was measured using a digital densitometer and related to the equivalent density of aluminium. The density of the image of the apical area of the socket was similar in control and desalivated groups (P > 0.05) throughout the study. However, the density of the image of the crestal area of the socket was lower (P < 0.01-0.001) between days 21 and 60 in desalivated rats. This suggests that desalivation causes a long-term delay in socket healing.

Absorptiometry, Photon↗
PubMed1992

The significance of idiopathic osteosclerosis found in panoramic radiographs of sporadic colorectal neoplasia patients and their relatives.

Osteosclerotic lesions in the mandible are reported with increased frequency in patients with colorectal neoplasia. Panoramic radiography has been suggested to detect high-risk patients among relatives of patients with hereditary adenomatous disease and sporadic colorectal cancer. The present study was undertaken to compare the incidence of idiopathic osteosclerotic lesions in patients with sporadic colorectal cancer and their first-degree relatives with the incidence in the general population and to determine whether panoramic radiographs are a reliable method to screen for early detection of risk of colorectal cancer. A total of 283 patients were interviewed and radiographically examined. Idiopathic osteosclerosis appeared in significantly increased incidence only in patients with colorectal cancer or adenomas and a first-degree relative with CRC (chi 2 = 7.214; p less than 0.01, and chi 2 = 4.1827; p less than 0.05 respectively). The incidence was not increased in first-degree relatives of patients with colorectal cancer or adenoma. Therefore panoramic radiographs cannot be the only screening tool for early detection of patients at high risk of colorectal cancer.

Adenoma↗
PubMed1990

The anterior buccal mandibular depression: physical and radiologic features.

The anterior buccal mandibular depression (ABMD), an anatomic variation not previously mentioned in the dental literature, is considered. Its physical and radiologic configuration is evaluated, and its significance in the differential diagnosis of radiolucent lesions in the anterior portion of the mandible is discussed. The general prevalence of ABMD was found to be 19.8%, with a significantly higher prevalence in children (p less than 0.001). In the majority of cases, the depression was radiologically detected. The radiopacity of the area was significantly dependent on depth of the depression (p less than 0.001). The radiographic image of the ABMD resembles, in many cases, the image of the less common anterior lingual salivary gland depression. The relatively high frequency of the ABMD indicates the importance of recognizing its radiologic features.

Adolescent↗
PubMed1990

Prediction of efficacy of bitewing radiographs for caries detection.

Although bitewing (BW) radiographs play an indispensable role in the detection of interproximal caries, it is not always clear when they should be made. The present study was designed to test the hypothesis that a person's caries and restorative history may be predictive of his or her caries future. Full-mouth radiographic examinations (FMX) and subsequent BW radiographs from 349 adults (age 20 or more) selected at random were examined. Possible risk factors for caries recorded for each patient included the number and type of carious lesions and the restorative experience of the patient. Linear logistic regression models were evaluated to estimate the efficacy of the possible risk factors as predictors of the presence of caries on the BW radiographs. Of the 349 adults examined, 91 (26%) had one or more new carious lesions at the time of their BW examination. The probability of caries in this population at the time of the BW examination increases both with lengthening interval between the FMX and the BW radiographs and with the number of restorations at the time of FMX. A regression model was adopted that estimates the probability of caries being detected on BW radiographs. We found that to provide the most good for the most patients (minimize cost), the threshold level for ordering follow-up radiographs should be when the probability of detecting caries is 5%. It may be seen that even when a person has no caries or restorations at the time of the FMX there will be a 5% chance that BW radiographs will reveal the presence of caries 1.5 years later. The 5% threshold is reached sooner in the presence of caries or restorations.

Adult↗
PubMed1990

Densitometric measurement of radiopacity of Gutta-percha cones and root dentin.

National and international standards require that gutta-percha cones be sufficiently radiopaque to be distinguished from natural structures such as dentin and to permit evaluation of the density of the root canal filling. Discs, 1-mm thick, made from 15 commercial and experimental brands of gutta-percha cones, were tested for their compliance with the requirements. The radiopacity of 1-mm thick root dentin slabs was similarly measured with a photo-densitometer. All radiographs were made on D-speed occlusal film and replicated on E-speed film. The mean radiopacity of the gutta-percha discs on D-speed film was 7.26 mm of aluminum equivalent and 7.53 mm on E-speed film, greatly exceeding the minimal requirement of 3 mm. The difference in the values obtained with the two film types was not significant, suggesting that E-speed films may be used for the test. Dentin slabs were uniform in their radiopacity, equivalent to 1 mm of aluminum, confirming previous findings. In view of complaints of insufficient clinical performance, the present minimal requirement for radiopacity of gutta-percha cones seems too low.

Densitometry↗
PubMed1989

The anterior buccal mandibular depressions: ontogeny and phylogeny.

The frequency of an anterior buccal depression in the mandible (ABMD), or a mental fossa, is reported on 970 human mandibles of various groups and different ages, as well as in 38 mandibles of nonhuman primates. The ontogenetic and phylogenetic significance of the results relevant to development of a chin in Homo sapiens is discussed. The ABMD is also compared with the occurrence of a lingual mandibular depression.

Adult↗
PubMed1987

E-speed dental films processed with rapid chemistry: a comparison with D-speed film.

Image quality of E-speed film processed in four rapid chemistry solutions was evaluated and compared to that of D-speed film. One-hundred-twenty films (60 E-speed and 60 D-speed) were exposed with the use of a quality-control phantom and processed in four different rapid solutions. The images were evaluated for speed, contrast, fog and base, resolution, and granularity, and the useful lifetime of the solutions was determined. E-speed film processed with rapid chemistry produced images equal in quality to D-speed film in the range tested (70 to 90 kVp). Fog and base levels of E-speed film were greater than those of D-speed film. The resolution and granularity of the images were equal and were judged adequate in both film types, regardless of the chemistry used. Rapid processing solutions were found to have a 10% to 15% shorter useful lifetime with E-speed film than with D-speed film. The processing of E-speed film in rapid chemistry is recommended for emergency care and endodontics.

Densitometry↗
PubMed1986

Efficiency of the cervical lead shield during intraoral radiography.

The cervical lead shield was compared with the conventional lead apron with regard to efficiency of protection against radiation during a full-month survey (fourteen periapical and two bitewing radiographs). The study was performed on a Temex tissue-equivalent human phantom, and thermoluminescent dosimetry was used to measure radiation absorption in the ovaries, testes, and thyroid gland areas. Results showed that the cervical shield significantly reduces the amount of radiation to the skin in all three areas and is equally as effective as the combination of lead apron and thyroid shield. It is therefore recommended as a protective measure during intraoral radiography.

Equipment Design↗
PubMed1986

Relationship between the apices of the lower molars and mandibular canal--a radiographic study.

The study was performed on forty-six randomly chosen dry mandibles. The molar areas of each mandible were radiographed by the paralleling technique, and an additional radiograph at -20 degrees angulation of the same area was taken. Measurements of the distance between the upper border of the mandibular canal and the root apices of the first and second molars were taken. The location of the mandibular canal in the buccolingual plane was determined. The obtained data were statistically evaluated. Statistically significant symmetry of the relationship of the mandibular canal to the root apices was established between the right and left sides of the same mandible. In the majority of cases the mandibular canal was buccal to the apices of the second molar, and in the first molar area the canal was lingual to the root apices in almost half of the cases. Most frequently, the upper border of the mandibular canal was located 3.5 to 5.4 mm below the root apices of both first and second molars. In no case was the mandibular canal found in close proximity, both in the vertical and in the buccolingual planes, to the first and second molar apices.

Adult↗
PubMed1986

New concept in chemoprophylaxis of bacterial endocarditis resulting from dental treatment.

Bacteremia following dental procedures may lead to bacterial endocarditis in susceptible patients. Traditional methods of chemoprophylaxis with a parenteral loading dose of penicillin followed by oral penicillin have proved impractical outside the hospital. In 1978, it was suggested in England that amoxicillin be substituted as the drug of choice in the prophylaxis of bacterial endocarditis. The recommended mode of treatment was a single oral dose of 3 g amoxicillin administered 1 hour before onset of the dental procedure. Amoxicillin is absorbed to a greater extent and more rapidly than penicillin V. It maintains its effectiveness throughout the critical postoperative period at concentrations well over the minimum necessary to combat Streptococcus viridans. Amoxicillin has two mechanisms of protection: bactericidal and inhibition of bacterial adherence to the thrombotic vegetation on injured heart valves. Data obtained from 206 susceptible patients undergoing dental treatment under chemoprophylaxis with amoxicillin showed that in no case did infective endocarditis occur. Only in 13.1% of the patients could very mild side effects of this drug be observed. With this new method, there is a higher incidence of patient compliance and administration is easier to supervise.

Adult↗