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Biomedical subjects

I Fukuda

Publications and source records attributed to I Fukuda.

At least 181 records · Page 10Linked to original sources
PubMed1983

Coronary artery aneurysm associated with aortitis syndrome diagnosed pre- and intraoperatively.

Aneurysm of the coronary artery associated with aortitis syndrome is extremely rare. This is a case report of a left coronary artery aneurysm associated with aortitis syndrome. The patient was a 47-year-old woman who complained of palpitation and dizziness on exertion. Aortogram revealed occlusion of the arch vessels, infrarenal aortic stenosis, and a fusiform aneurysm of the left coronary artery. There was neither an intraluminal thrombus nor occlusive changes in the coronary arteries. Severe systolic hypertension nearing 300 mmHg was present in the ascending aorta. Severe hypertension and direct extension of inflammation to the coronary artery seemed to be important factors for the formation of the aneurysm. To resolve the severe hypertension, a bypass operation between the ascending aorta and the abdominal aorta distal to the stenosis was performed. The postoperative course was uneventful and blood pressure was reduced.

Aneurysm↗
PubMed1981

Long-term survivors with nonresectable advanced carcinoma of the rectum.

Two patients with advanced rectal cancer, women aged 73 and 49 years, have survived more than nine years with chemotherapy only and no surgical removal of the disease foci. In one patient, the tumor completely disappeared, and in the other the tumor stopped growing and its size remained unchanged. The reason for this long-term survival appears to be a high susceptibility to anticancer agents and persistence of enhanced host immunity.

Adenocarcinoma↗
PubMed1980

Purification by affinity chromatography and physicochemical properties of the guanine-specific ribonuclease of Fusarium moniliforme.

Ribonuclease F1, the guanine-specific ribonuclease of Fusarium moniliforme, was purified to homogeneity by a combination of ethanol fractionation, affinity chromatography and DEAE-cellulose column chromatography. The adsorbent for the affinity chromatography was synthesized by the coupling of periodate-oxidized guanosine 5'-monophosphate to aminohexyl agarose followed by sodium borohydride reduction. Ribonuclease F2, the minor component, was also purified to near homogeneity by the same procedure. Ribonucleases F1 and F2 had the same molecular weight (about 11,000) as determined by gel filtration and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. They also showed the same amino acid composition and differed only in the isoelectric point: 4.10 for F1 and 3.96 for F2.

Amino Acids↗