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Biomedical subjects

I Enge

Publications and source records attributed to I Enge.

71 records · Page 4Linked to original sources
PubMed1968

[Urography].

Explore the source record for details and available documents.

Humans↗
PubMedDate not supplied

In vitro evaluation of a new temporary venous filter: the Spring filter.

PURPOSE: To evaluate in vitro the function efficacy of a new variable-sized, temporary venous filter, the Spring filter (SF). METHODS: The SF was tested in a flow phantom, using flexible, thin-walled polyethylene tubes 12, 14, and 16 mm in diameter to simulate veins. Clots of three sizes were used: 6 x 10 mm, 6 x 20 mm, 9 x 20 mm. Filter deployment was performed, ensuring that its functional diameter after placement was a predetermined multiple of the radius 'r' of the tube: 3.0r, 2.8r, 2.6r, 2.4r. The terminal coil was visually examined for changes in configuration. Clot retention by the filter for a period of 3 min was recorded as a success. The baseline intraluminal pressure and the maximum pressure reached after clot introduction were recorded. The trapping ability was calculated from the results for 10 clots. The effect of the following parameters on filter function were studied: size of embolus, caliber of simulated vein, and functional diameter of filter. RESULTS: The filter configuration was stable. Not a single instance of axial tilting occurred on deployment. Functional diameter was the major determinant of filter function. One hundred percent of clots were trapped irrespective of clot size and tube caliber when the functional diameter was 3.0r. Only 73% (95% confidence interval (CI): 57% - 88%) and 77% (95% CI: 61% - 92%) of small emboli were held up by the filter when the functional diameters were 2.6r and 2.4r, respectively (p = 0.0001). A significant reduction in clot trapping was encountered even with medium clots when the functional diameter was 2.4r (p = 0.02). CONCLUSION: Against the background of available data on retrievable vena caval filters, the current model of SF warrants further investigation.

Equipment Design↗
PubMedDate not supplied

Induced thrombosis in the pig inferior vena cava: a model of deep venous thrombosis.

PURPOSE: To establish a new animal model of deep venous thrombosis. MATERIALS AND METHODS: Fifteen young pigs underwent temporary interruption of the inferior vena cava (IVC) below the entry of the right renal vein by means of either a silicone band (surgical technique, n = 6) or an intraluminal balloon catheter (endovascular technique, n = 9), followed by injection of absolute ethanol. Lumbar veins within 3 cm below the obstruction were ligated or occluded interventionally. The iatrogenic caval obstruction was relieved after 2 days. RESULTS: Procedure-related mortality was 33% (n = 2) and 11% (n = 1) for the surgical and endovascular groups, respectively. An adherent, occlusive thrombus was found in all four of the remaining surgically treated animals and in six of eight animals treated percutaneously. The IVC remained patent in two animals in whom balloon migration occurred. Severe caval stenosis invariably occurred after surgical banding. CONCLUSION: IVC thrombi suitable for the study of various recanalization therapies can be reliably created with this pig model.

Angioplasty, Balloon↗
PubMedDate not supplied

Iohexol in phlebography of the leg. A comparative investigation with meglumine metrizoate.

Comparing iohexol 240 mg I/ml, iohexol 300 mg I/ml and meglumine-Ca metrizoate 200 mg I/ml in phlebography of the leg in patients on or without anticoagulants, no sign of postphlebographic thrombosis was found using the 125I-fibrinogen uptake test and repeat phlebography. More adverse reactions occurred with metrizoate than with iohexol. Metrizoate provided significantly poorer demonstration than the two iohexol concentrations with higher iodine content.

Adult↗
PubMedDate not supplied

Water-soluble contrast media in radiography of small bowel obstruction. Comparison of ionic and non-ionic contrast media.

Fifty patients with possible gastrointestinal obstruction, referred for enteric follow-through examination, were randomized for a double-blind, parallel comparison of the hyperosmolar contrast medium Gastrografin and the low-osmolar Omnipaque. The result was that Omnipaque retained its radiographic density in the small bowel better than Gastrografin. Omnipaque was thus a better alternative than Gastrografin in follow-through examinations of intestinal obstruction. Also, 23 patients out of 28 with small bowel obstruction due to peritoneal adhesions, had spontaneous relief of symptoms during the observation period following contrast medium ingestion with no significant difference between the two media. This indicated that enteric follow-through procedures may have a therapeutic efficacy similar to the treatment of small bowel obstruction using nasogastric suction and gastrointestinal rest. Possible mechanisms for this action of the contrast media are discussed.

Aged↗
PubMedDate not supplied

Phlebography. Survey and present state.

Milestones in the history of phlebography are shortly reviewed. The present state of phlebography with emphasis upon the role of new nonionic contrast media is presented.

Clinical Trials as Topic↗