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Biomedical subjects

I Bakran

Publications and source records attributed to I Bakran.

At least 37 records · Page 2Linked to original sources
PubMed1977

[253 patients with acute pancreatitis treated at the surgical clinic in Zagreb].

253 patients with acute pancreatitis were treated in clinic for surgery in Zagreb through last 23 years. The most frequent cause of pancreatitis were diseases of biliary tract, obesity, vascular deseases, alcoholism etc. In the symtomatology, the pain was present in all patients and majority of them had abdominal symptoms as well. Most of the patients came to the treatment within the firsts 24 to 48 hours. Besides Trasylol various conservative therapy was applied and some patients were operated either on billiary ducts or on pancreas. 85 patients had to be operated again on billiary tract afterwards. From 253 patients treated 24 died (9,48%) because of the necrosis of pancreas and alterations on various other organs.

Acute Disease↗
PubMed1977

[Carcinoma of the stomach].

During the period from 1961 to 1976 884 patients with cancer of the stomach were registered and treated at surgical Clinic in Zagreb. From those cases 607 (68,66%) were men and 277 (31,34%) women. The age of patients varied from 50 to 70 years. More of them were pensoners and farmers. From those patients 196 (22,17%) were smokers and 176 (19,9%) alcoholics. All of them had usual symptoms of cancers of the stomach, mainly combined with loss in weight, loss of appetite and gastrointestinal bleeding. Average duration of symptoms before coming to the Clinic was six months. Preoperatively 88 (9,9%) were inoperable. By explorative laparotomy 175 (17,5%) inoperable cases were found. At 261 (29,5%) palliative operations were done. 63 (7,1%) patients refused to be operated. Using different methods 297 (35,5%) patients were radical operated. The most frequent were adenocarcinoma and after them gastric ulcers which became malignant. The most frequent causes of death were peritonitis and pneumonia. 7,3% of radically operated patients survived 5 years.

Adult↗
PubMed1977

The effect of alternate-day prednisone therapy on cortisol secretion rate in corticosteroid-dependent asthmatics.

The effect of alternate-day prednisone regimen (nine-patients) on cortisol secretion rate was compared with daily therapeutic regimen (ten patients) in corticosteroid-dependent asthmatics. Only the alternate-day regimen did not suppress the adrenal function. The therapeutic efficacy of both regimens was equal. The advantages of alternate-day corticosteroid therapy are presented and the optimal way of starting this therapy discussed.

Adrenal Cortex Hormones↗
PubMed1977

Cortisol secretion rate during beclomethasone dipropionate aerosol therapy in bronchial asthma.

Beclomethasone dipropionate is a new synthetic corticosteroid for the inhalatory treatment of bronchial asthma. The effect of beclomethasone dipropionate aerosol (400 mug/day/j weeks) on the cortisol secretion rate in comparison with prednisone per os (10 mg/day/4 weeks) was investigated in 12 patients with allergic bronchial asthma. There was no suppression of the adrenal cortex in the course of beclomethasone dipropionate inhalation, while prednisone significantly suppressed adrenal cortex function.

Adrenal Cortex↗
PubMed1976

Electrocardiographic changes in rats after inhalation of dichlorotetrafluoroethane, Arcton 114, C2Cl2F4.

The effects of dichlorotetrafluoroethane, Arcton 114, on the heart of rats were examined in 17 white rats. The animals inhaled dichlorotetrafluoroethane for 1 or 1.5 min. Severe electrocardiographic changes including marked bardycardia, atrioventricular heart block of the second degree and complete heart block were registered. Cardiac standstill appearing 11 to 31 min after inhalation was a death cause in all rats. These results are similar to our previous results concerning the effects of dichlorodifluoromethane (Arcton 12) on the heart of rats.

Aerosol Propellants↗
PubMed1976

The effect of propranolol, prindolol, practolol and verapamil versus placebo on exercise induced tachycardia in patients with ventricular preexcitation.

Propranolol, prindolol, practolol and verapamil have been given orally in a fixed dose to subjects with preexcitation syndrome in a cross over study. The effect on exercise induced tachycardia, prevention of tachyarrhythmias and normalization of heart rate after exercise was investigated. Propranolol, practolol and prindolol significantly (p less than 0.01-0.05) reduced the heart rate at rest and during exercise and favourably influenced the normalization of the heart rate after exercise. The effect on effort tolerance (work done till the submaximal heart rate was reached) was significantly better after propranolol (versus prindolol and verapamil) and practolol (versus verapamil) only. Verapamil showed a consistent effect only given intravenously in paroxysmal tachycardia while in the majority of patients there was no difference between oral verapamil and placebo.

Adult↗