Search PubMed⌕ Search

Biomedical subjects

I A Sytnik

Publications and source records attributed to I A Sytnik.

At least 37 records · Page 2Linked to original sources

[Joint action of nitrofuran preparations and bile acids on bacteria of the genus Proteus].

Sensitivity of 25 fresh isolates of Proteus to some nitrofuran drugs most widely used in the clinical practice, such as furacillin, furagin, furazolidone and nitrofurantoin was studied. When the drugs were used in combination with some bile acids, i.e. desoxycholic, dehydrocholic, cholic and glycocholic acids, significant in vitro potentiation of the antibacterial activity of the nitrofurans against the isolates was observed. The combinations of the drugs with desoxycholic acid proved to be most effective. In the presence of this acid the bacteriostatic dose of the drugs decreased several thousand times. Combination of the nitrofurans with the other acids resulted in an increase in the antimicrobial activity amounting to several hundred times. The combinations of the drugs with the bile acids had not only bacteriostatic but also bactericidal effect.

Bile Acids and Salts↗

[Action of microbe-antagonists on bacilli and corynebacteria of the skin of the breast in nursing women].

Five microbes-antagonists are studied for their inhibitory action on 769 strains of bacilli (241) and corynebacteria (528) isolated from the mammary gland skin of 120 nursing women on the 2nd-5th day after labour. Escherichia coli M-17 and Mycococcus krassilinikovi are established to possess the highest antagonistic properties against the spore-bearing aerobic and coryneform bacteria. Bifidobacterium bifidum has exerted a moderate antagonistic action on the culture under study, Bacillus subtilis has exerted a strong inhibitory action on corynebacteria. B. licheniformis has slightly inhibited the both bacterial groups.

Antibiosis↗