[Prognostic value of HL-A typing in patients with prodromal symptoms of ankylosing spondylitis (Sp. a.)].
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Biomedical subjects
Publications and source records attributed to H Zeidler.
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The Weissenberg rheogoniometer was used to measure viscosity, normal force and the number of molecular entanglements, calculated from a shear modulus obtained by prestationary experiments, in inflammatory and non-inflammatory synovial fluid effusions. The rheological properties show greater pathological change in the inflammatory synovial fluid samples than in the non-inflammatory. Variation in the hyaluronic acid concentration is only partly responsible for the pathological rheology. Initial experiments with a normalization method for the viscosity flow curves suggest the possibility of determining changes in polymerization or structure of the hyaluronic acid by rheological measurements.
Conventional x-ray and xeroradiographic technique were compared in a modified blind study in order to evaluate its efficiency to detect calcifications of the cartilage. Using both techniques knees, hands, and pelvic joints were examined in 16 patients with proven chondrocalcinosis. Three different radiologists evaluated radiological films and xeroradiograms independently. Their results were classified in correct, false negative, and false positive groups. All examiners achieved the best results with xeroradiography. Due to special characteristic features in xeroradiography even fine calcifications were recognized in most cases. By this method the "false negative" results were reduced to almost zero. On the other hand, the twenty percent "false positive" results in conventional radiological technique was eliminated by xeroradiography.
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27 women with rheumatoid arthritis had elevated depression and social introversion scores in the Minnesota multiple phasic personality inventory (MMPI) tests, whereas their somatic activity appeared reduced. Age of the patient at time of investigation apparently had no influence on the degree of psychological changes, but was reflected in an increased social introversion. Most important for the degree of psychological impairment was the height of the ARA index, which correlated positively with the neurotic triad as well as the psychasthenia scale in the MMPI. An elevation of the neurotic triad is common in many somatic disease. Patients with rheumatoid arthritis had an additional, introversion and depression, and decreased somatic activity.
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