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Biomedical subjects

H Yokoi

Publications and source records attributed to H Yokoi.

At least 181 records · Page 10Linked to original sources
PubMed1987

Analysis of donor criteria for the prediction of outcome in clinical liver transplantation.

The results of 219 orthotopic human liver transplants performed during 1985 at the University of Pittsburgh were reviewed to determine whether donor parameters could be used to predict the quality of early graft function. Multivariate discriminant analysis demonstrated that traditional parameters of donor assessment are unreliable predictors of poor graft function. Furthermore, 56% of the donors considered poor by conservative selection criteria produced livers with good early posttransplant function. Survival of recipients of primary allografts from donors rated poor was no different than survival of recipients of allografts from donors rated good.

Adolescent↗
PubMed1987

Acute bilateral deafness with nephritis: a human temporal bone study.

Temporal bone pathology is described in a 37-year-old man who had acute, bilateral, profound sensorineural hearing loss without improvement 4 months before death. The patient had suffered from low complement nephritis, for which he had received prednisolone therapy. Autopsy revealed malignant lymphoma with non-Hodgkin's type, membranous proliferative glomerulonephritis and necrotizing vasculitis of middle and small arteries. In the temporal bone study, pathological changes were limited to the cochlear region. The vestibular structure showed no detectable pathological changes. The changes included total absence of the organ of Corti, atrophy and/or disappearance of the stria vascularis in the upper turns, collapse of Reissner's membrane in the middle turn, and new bone formation in the apical turn.

Adult↗
PubMed1985

A new portable device for recording 24-h indirect blood pressure in hypertensive outpatients.

To simplify 24-h blood pressure (BP) recording in hypertensive outpatients, we devised a new portable, automatic BP recorder and studied its accuracy and usefulness. The fully automatic recorder, measuring 5 x 16 x 18 cm with a cuff of usual size, weighs approximately 1 kg and is driven by a rechargeable battery. The cuff is inflated by a compact CO2 cartridge and two microphones are used to detect differentially the Korotkoff sounds in the upper arm. Systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) are automatically measured, displayed with the time of measurement, and recorded on a memory card at intervals of 15 min for 24 h. This equipment has high noise immunity and works very quietly. It predicts approximate BP during the period of increasing cuff pressure, and measures BP more quickly than the conventional method (the time required for each measurement was reduced by about half). Afterwards, mean values with standard deviations, trendgrams and histograms of BP and HR over a certain period of time can be displayed and recorded with an accessory analyser. The accuracy of the BP values recorded by this device were compared with those measured by the auscultatory method. The average differences were -0.6 +/- 2.1 (s.d.) mmHg for SBP and 0.2 +/- 3.0 mmHg for DBP (n = 152). The BP values by this method were also compared with those obtained directly from the brachial artery, the differences being -5.8 +/- 5.9/0.3 +/- 6.0 mmHg (n = 85). In 30 ambulatory hypertensive patients, 24-h BP was recorded using this recorder.(ABSTRACT TRUNCATED AT 250 WORDS)

Auscultation↗
PubMed1984

Blast injury to sensory hairs: a study in the guinea pig using scanning electron microscopy.

Guinea pigs were exposed to a blast (maximum 1.0 kg/cm2) of nitrous gas for 0.2 s through the external auditory canal. Then, they were either killed immediately, 1 day, 3 days, 1 week, 2 weeks, or 4 weeks after exposure to the blast. The morphological changes of the cochlear sensory hairs were examined by means of a scanning electron microscope. Changes in the sensory hairs of the animals exposed to the blast for 1 s were examined in the same manner. The results of these experiments show that sensory hairs of the basal and the second turns were damaged more markedly than those of the third and subsequent turns. Outer sensory hairs were damaged more than inner ones.

Animals↗
PubMed1984

Defense mechanism of the cochlear aqueduct against infection. A morphological study in the guinea pig.

Guinea pigs were used in this study. Physiological saline, india ink, and Staphylococcus aureus were injected into the cisterna magna, and S. aureus was also injected into the scala tympani. Changes in the microstructure of the cochlear aqueduct were observed by light microscopy and also by scanning electron microscopy, mainly by means of fracture preparations. From these experimental results, it could be confirmed that the periotic duct tissue of the cochlear aqueduct reacted especially to bacterial infection.

Animals↗
PubMed1984

Aminergic innervation of cerebral veins. Histochemical comparison with extracranial veins.

The density and distribution pattern of aminergic nerve fibers in intracranial and extracranial veins were compared by means of catecholamine histofluorescence studies. Extracranial veins (internal jugular, inferior caval, portal, renal, internal iliac, and femoral veins) showed quite a uniform distribution pattern. Large veins (jugular, caval, renal, and iliac veins) revealed a spiral pattern, and small veins presented as a meshwork (femoral vein) or in a longitudinal pattern (a branch of the femoral vein). In contrast, intracranial veins displayed more complex patterns: the dural sinus showed a longitudinal pattern and the internal cerebral vein and the superficial vein of Labbé revealed a meshwork of nerve fibers. The aminergic fibers were denser in cerebral veins (dural sinus and internal cerebral vein) than in extracranial veins. The complex distribution and the density of aminergic fibers in cerebral veins suggest that the aminergic innervation of the circulatory system may be more important in the brain than in the extracranial organs.

Amines↗
PubMed1984

[Adjuvant BCG immunotherapy for breast cancer (T1N0M0, T2N0M0)].

The present study was performed to evaluate the effect of BCG immunotherapy for breast cancer (T1n0M0, T2n0M0) in nonrandomized series. During a 5-year follow-up study, patients in the BCG-treated group suffered neither recurrence nor death, while the historical control group had 6 cases of recurrence and 5 cases of disease death. As seen in our series, we concluded that breast cancer patients should be advised to accept adjuvant BCG immunotherapy after mastectomy.

Adjuvants, Immunologic↗
PubMed1983

Electron--nuclear-double-resonance studies of spinach plastocyanin.

Electron--nuclear-double-resonance (ENDOR) studies of spinach plastocyanin revealed that 14N-hyperfine couplings from its two co-ordinated imidazole groups are characteristically small in anisotropy and relatively high in ENDOR frequencies and that the two imidazole groups are magnetically equivalent. The relatively strong copper-imidazole co-ordinate bonds of plastocyanin are interpreted to be a result of the coexistence of a strong copper--thiol co-ordinate bond.

Binding Sites↗
PubMed1983

Effects of hypertonic mannitol on renal function in open heart surgery.

An extracorporeal bypass was performed in mongrel dogs for 2 hours with or without hypertonic mannitol infusions. In animals given mannitol, the plasma osmolality was elevated maximally to 344 +/- 7.1 mOsm/L and the urine volume was maintained well during bypass. A hypertonic mannitol solution was effective in maintaining the CPAH during and after bypass, but was not effective in minimizing the reduction in Ccr. When the mean arterial pressure during bypass was kept at 60 mmHg, the carbon filling rates in glomeruli showed the favorable effects of mannitol upon renal function, but no effects were observed at a mean arterial pressure of 80 mmHg. In 11 patients who had undergone a bypass lasting more than 2 hrs with mannitol infusions, the plasma osmolality reflected the serum mannitol level and reached 320 +/- 11.0 mOsm/L at 150 min of bypass. The mean urine volume was 5.0 +/- 3.3 ml/min/M2 during the bypass, which was about 7 times as great as before the bypass. The Ccr increased during the first 30 min of the bypass, but it fell to about one half of the initial value after 90 min of the bypass. It was concluded that a hypertonic mannitol solution is effective in maintaining the RPF and urine volume during and after the bypass and that it also preserved the glomerular perfusion even at a low arterial pressure.

Acute Kidney Injury↗
PubMed1982

Evidence that stimulatory factor(s) of RNA polymerase II participates in accurate transcription in a HeLa cell lysate.

Antibody raised against S-II, a stimulatory factor of RNA polymerase II from Ehrlich ascites tumor cells, inhibited accurate transcription from adenovirus 2 major late promoter in a HeLa cell lysate. Manganese prevented accurate transcription, but it was essential for expression of the stimulatory activity of S-II. The results indicate that protein(s) cross-reacting immunologically with S-II in a HeLa cell lysate is essential for accurate transcription of truncated DNA, but the stimulatory activity of this factor(s) is not necessary for accurate transcription of truncated DNA.

Animals↗