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Biomedical subjects

H Yamane

Publications and source records attributed to H Yamane.

At least 163 records · Page 9Linked to original sources

[Imaging diagnosis of hepatobiliary system and pancreas--computed tomography, ultrasound and angiography].

CT, US and angiography have become the most important examinations in the diagnosis of hepatobiliary and pancreatic diseases. Therefore updated and precise knowledge of these modalities are mandatory not only for the diagnosis but also for the interventional radiology in this field. General review on the advantages and limitations of these medical images are described.

Angiography↗

Location of intravenously injected kanamycin sulfate in the middle ear mucosa.

Twelve guinea pigs were treated with intravenous kanamycin sulfate (KM) and sacrificed 2, 5, 10, and 30 min later to investigate its location in the middle ear mucosa, especially in the Eustachian tube (ET). Immunological examinations evidenced KM in the epithelial and subepithelial layers of the ET on each occasion of observation. But, it was never recognized in the tubal gland. These observations might indicate that clinically used drugs easily get to the ET except for the tubal gland which might have some barrier mechanism against foreign bodies.

Animals↗

Identification of Ten Gibberellins from Sporophytes of the Tree fern, Cyathea australis.

Ten gibberellins (GAs) have been identified by Kovats retention indices and full mass spectra from GC-MS analysis of purified extracts of sporophytes of the tree-fern, Cyathea australis. These include the known GA(1), GA(4), GA(9), GA(15), GA(24), GA(35), and GA(58) and three new GAs, 12beta-hydroxyGA(9) (GA(69)), 12alpha-hydroxyGA(9) (GA(70)) and 12beta-hydroxyGA(4) (GA(71)). The structure of GA(71) was established by the preparation and characterization of its methyl ester (as a metabolite of GA(4) methyl ester in a culture of prothallia of Lygodium japonicum).

Journal Article↗

Auditory brain-stem response and temperature: relationship in the guinea pig.

The neurological applications of the auditory brain-stem response depend largely on the stability of the interval between the peaks of waves I and V. Using guinea pigs, it was demonstrated that hyperthermia and small temperature changes, as well as hypothermia, may affect interpeak latency (IPL) sufficiently to affect its clinical interpretation. The relationship between temperature and IPL is specified by a power function such that there is a 5.3% increase in IPL for a 1 degree C drop. Although the constant for humans may differ from that of guinea pigs, the results of this animal study demonstrate that the relationship between temperature and IPL is invariant from 27 degrees C to 40 degrees C.

Animals↗

Free-floating cells in the endolymphatic sac after surgical utricular nerve section.

Free-floating cells (FFC) in endolymphatic sac (ES) were microscopically examined, counted, and statistically studied in 8 squirrel monkeys after the unilateral section of the utricular nerve (UNS). After the operation these monkeys were kept for 17-38 days until the acquisition of functional (locomotor balance) compensation was completed. The result showed twice more FFC in the ES on the operated side, than those on the nonoperated side. The result showed a significant increase (p less than 0.05) of FFC in the ES under the pathological condition with autogenous debris in the endolymphatic space, and proved the existence of some reactive role of the ES to the labyrinthine insult.

Animals↗

Otoconia degradation.

During certain stages of mammalian inner ear development, small crystallized bodies which resemble otoconia may be found in the endolymphatic sac. In order to examine whether the endolymphatic sac plays any part in the process of degradation and dissolution of otoconia, we made an electron-microscopic examination on the endolymphatic sac of fetuses and adult guinea pigs injected with streptomycin sulfate (SM). In 30-day-old fetal guinea pigs we found miniature otoconium-like bodies (OLBs) in the endolymphatic sac and a giant OLB in the endolymphatic duct. In adult animals we found no otoconia in the endolymphatic sac following SM intoxication. However, the results suggested that both the dark cells of the utricle, as well as the non-sensory epithelium of the saccule, may be engaged in the absorption and dissolution of otoconia.

Animals↗

[Several factors influencing the male sexual function in patients with atherosclerotic disease].

Patients with arteriosclerosis obliterans (ASO, n = 58), abdominal aortic aneurysm (AAA, n = 27) and the combined disease (n = 4) were the subjects of this study. All patients were evaluated by retrograde aortography and questioned personally as to their present male sexual function. The penile and ankle systolic pressure index (PSPI and ASPI) of patients with ASO were measured using a Doppler device, but in the patients with AAA, only the PSPI was taken. Several factors relating to male sexual function, such as, age, PSPI, ASPI, sites of the arterial occlusion or dilatation, classification of the ischemic symptoms according to Fontaine's category, numbers of pulsations of the femoral artery, were statistically analysed. All of the patients with both diseases, 66 percent of those with ASO and 52 percent of those with AAA were impotent. In the patients with AAA, the PSPI of the potent group was not significantly higher than that of the impotent group; however, in patients with ASO, the PSPI of the former group was significantly higher than that of the latter group. In the patients with ASO, a significant correlation between the PSPI and the ASPI (r = 0.49, p less than 0.01) was found. When a PSPI value (PSPI = 0,70) was chosen as a demarcation between the impotent group and the potent group, 84 percent of the patients with ASO were correctly classified. However, when the ASPI (ASPI = 0.45) was used, only 69 percent were properly classified.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗