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Biomedical subjects

H Witschel

Publications and source records attributed to H Witschel.

At least 73 records · Page 4Linked to original sources
PubMed1982

[Congenital solitary fibromatosis of the eyelid (author's transl)].

Clinical and histopathological findings in a case of localized congenital fibromatosis of the lower eyelid are presented. The histological and electron-microscopic features point to the hamartomatous origin of this tumor with partial differentiation of its cells towards myofibroblasts. In spite of the diffusely infiltrating growth and the tendency for local recurrences, metastases have never been observed. Therefore, local excision is the appropriate therapy.

Dermoid Cyst↗
PubMed1981

Malignant mixed tumor of the lacrimal gland. A clinicopathologic report of two unusual cases.

Two cases of malignant transformation in an originally benign mixed tumor of the lacrimal gland (pleomorphic adenoma) are presented. In both patients the unusual histopathologic appearance of the malignant component gave rise to considerable problems in clinical and histopathologic diagnosis. In one case of the malignant tumor had a sarcomatous appearance, while in the other there was sebaceous differentiation mimicking an adenocarcinoma of the Meibomian glands.

Adenocarcinoma↗
PubMed1981

[Chlamydial disease of the eye: a report on 27 cases. Clinical picture, differential diagnosis, treatment (author's transl)].

During the past five years a presumptive diagnosis of ocular chlamydial disease has been made in 90 patients consulting the outpatient department of Freiburg University Eye Clinic. The diagnosis was confirmed by different methods (giemsa stains, chlamydia cultures and serology, electron microscopy and histology) in 27 cases. The clinical spectrum included inclusion blennorrhea in newborns as well as inclusion conjunctivitis, TRIC keratoconjunctivitis and sporadic trachoma in adults. Presumably the incidence of the disease is much higher than indicated by our figures. We suspect a very high number of undiagnosed cases. These patients usually do not receive proper therapy (tetracyclin or erythromycin for at least three weeks) and their disease may run a protracted course with the risk of permanent eye damage.

Adolescent↗
PubMed1980

[Panuveitis].

Explore the source record for details and available documents.

Bacterial Infections↗
PubMed1980

Posterior polymorphous dystrophy of the cornea (Schlichting). An unusual clinical variant.

Three members of a family with dominant inherited endothelial dystrophy of the cornea are described. The father showed only subclinical disease with subtle endothelial blisters like those found in Schlichting's dystrophy. His daughter and grandson, however, both suffered from a peculiar, prominent, ring-shaped clouding of the cornea which progressed to severe edema, necessitating keratoplasty. Light, transmission, and scanning electron microscopy revealed an epithelial transformation of the endothelium. While the anterior banded part of Descemet's membrane was well-formed in the central cornea, it was missing in the periphery. This corresponded with the ring-shaped opacity and indicated a very early transformation of the endothelium in this area. We believe that this pedigree represents an unusual clinical variant of posterior polymorphous dystrophy of the cornea.

Adult↗
PubMed1980

[Epibulbar osteomas (author's transl)].

Epibulbar osteomas are benign tumors which are usually present at birth. Up to now 39 cases have been described in the literature. In the last three years 4 further cases have been found in the Freiburg, Hamburg, Marburg, and Munich University Eye Clinics. Epibulbar osteomas probably occur more often than is generally believed. The clinical and histological findings in respect of these tumors are discussed.

Adult↗
PubMed1978

[Reaction of ocular tissues to scleral-implant and encircling material: polyamide--silicone--polyester (author's transl)].

Twenty-two human eyes and one rejected Silastic sponge were examined histopathologically for the reaction of ocular tissues to buckling and encircling materials. The eyes were enucleated 22 days to 14 years following retinal detachment surgery. Silicone implants, Silastic sponges, and Mersilene bands were very well tolerated by the eye, whereas nylon threads caused a moderate and prolonged granulomatous inflammation due to their susceptability to enzymatic decomposition. This reaction, however, does not seem to be of major clinical importance, as the amount of nylon used in detachment operations is low. Atrophy of the underlying sclera can happen with any of the above-mentioned materials and depends mostly on mechanical factors of the implant and on the intraocular pressure. Even with total transcleral erosion of the buckling or encircling material, no severe histopathologic changes could be found in the overlying choroid and retina.

Choroid↗
PubMed1978

Congenital hereditary stromal dystrophy of the cornea.

Cornea from patients in two separate pedigrees showing dominant inheritance of a congenital nonprogressvie corneal clouding were examined by light and electron microscopy. The characteristic changes of abnormal corneal lamellae were widely and rather uniformly distributed throughout the stroma. The remaining corneal layers were normal. The findings are consistent with a diagnosis of congenital hereditary stromal dystrophy of the cornea, which differs greatly on both histologic and clinical grounds from the entity known as congenital hereditary endothelial dystrophy of the cornea.

Adolescent↗
PubMed1978

[Suture loosening after keratoplasty and methods for correction (author's transl)].

An analysis of histological and clinical findings in 102 keratoplasties confirms that suture loosening is often associated with defects found in Bowman's membrane and in the superficial stroma. These structures of the cornea serve as the major supporting layer for a suture. In cases of more generally weakened corneal tissue, like in keratokonus, suture loosening is also a relatively frequent occurance. In this paper we report on our experiences with correction methods, post-operative care and immunoprophylaxis after correction.

Corneal Transplantation↗