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Biomedical subjects

H Witschel

Publications and source records attributed to H Witschel.

At least 55 records · Page 3Linked to original sources
PubMed1988

[Retinal cryocoagulation in rubeosis iridis].

Patients with neovascularization of the iris were treated with cryocoagulation of the peripheral retina alone (Group A, n = 29), or in combination with cryocoagulation of the ciliary body (Group B, n = 19). The basic disease was either diabetic retinopathy or occlusion of the central retinal vein. After a follow-up of at least six months, a marked reduction in neovascularization of the iris was seen in most eyes. Intraocular pressure was reduced from a mean of 35.4 to 13.4 mm Hg in Group A, and from 55,2 to 6 mm Hg in Group B. A phthisis bulbi developed in six of 30 eyes (20%) in Group A and in 11 of 20 eyes (55%) in Group B.

Adolescent↗
PubMed1987

[Initial diagnosis of acquired immunologic deficiency syndrome (AIDS) by the ophthalmologist].

The authors report on two patients who presented with sudden loss of vision, due to irodocyclitis and retinochoroiditis in one patient and optic neuritis in the other. AIDS was diagnosed in both patients on the basis of a positive HIV antibody assay, lymphopenia, and a reduced helper-to-suppressor subset ratio. Soon afterwards, the patient with retinochoroiditis developed the full-blown picture of AIDS with cerebral involvement. Neither anticytomegaly treatment with DHPG nor triple therapy for toxoplasmosis was able to prevent the fatal course. The patient died within six months. In contrast, the patient with optic neuritis recovered full visual acuity. So far there has been no relapse, nor any opportunistic infection in other organs.

Acquired Immunodeficiency Syndrome↗
PubMed1987

[Pars plana lentectomy].

Pars plana lentectomy was performed in a total of 75 eyes of 63 patients. The main indications were congenital and infantile cataract, traumatic cataract, and complicated cataract associated with uveitis. The surgical technique, the difficulties encountered, and the intraoperative and postoperative complications are described. While there are hardly any problems associated with the operation and postoperative care in older patients, a number of difficulties occur in infants and small children. Of decisive importance here are, among other things, correct timing of the operation, a gentle surgical technique and disciplined optical rehabilitation, which requires close cooperation between the clinic and the parents. If these requirements are satisfied, the prognosis of congenital and infantile cataract can be considered favorable.

Adolescent↗
PubMed1986

[Malignant lymphoma of the eyelids].

A 51-year-old patient developed malignant lymphoma of both lower eyelids, which turned out to be immunocytoma of the lymphoplasmocytic subtype. The lymphatic tumor grew after several episodes of severe inflammation of the lids and conjunctiva in the presence of an underlying marked occupational allergy to chloramphenicol. The development of a so-called oculocutaneous immunocytoma from a reactive proliferation, its histological characteristics and its special clinical course are discussed on the basis of the present case.

Chloramphenicol↗
PubMed1984

[Neuroretinitis].

Eight patients presenting with the characteristic clinical picture of neuroretinitis are described. The decrease in visual acuity was caused by a papillitis, whereas the macular star developed later in the course of the disease when the visual acuity had already recovered. Five of our 8 cases were adults, a fact which demonstrates that neuroretinitis is not only confined to childhood. Three of the 8 cases were bilateral, two of them children. Two patients presented with neuroretinitis and additional inflammatory processes of other ocular segments (one with chorioretinitis and vasculitis; one with scleritis and uveitis), suggesting that a general vascular inflammation may be present in neuroretinitis. The macular star is produced by lipid-rich exudate in Henle's nerve fiber layer, thus giving the picture of stellate retinopathy. The exudate probably leaks from the disk due to a defect in the blood-tissue barrier or a loosening of the border tissue at the disk margin. The etiology of neuroretinitis remains an enigma. Serologic and cultural tests for preceding viral infections have so far been inconclusive.

Adolescent↗
PubMed1984

[Amebic keratitis: clinico-histopathologic case report].

The present paper describes a case of amebic keratitis in a 63-year-old female patient, who had been wearing hard contact lenses to correct myopia. The clinical course was characterized by early superficial corneal infiltrates accompanied by a marked iritis and excruciating pain. Later a ring abscess developed, combined with a disciform infiltration of the deep central stroma and a recalcitrant superficial corneal ulcer. The disease ran a very chronic course over more than 3 months. After various conservative treatments including topical steroids, antibiotics, antimycotic, and antiviral drugs, a penetrating keratoplasty had to be performed. The histopathologic examination of the corneal button revealed many encysted amebas and a few trophozoites which were classified by direct immunofluorescence as belonging to the genus Acanthamoeba (Hartmannella). Six months after keratoplasty the eye was quit without any signs of recurrence. As far as the authors know, this is the first reported case of an amebic keratitis associated with contact lenses.

Amebiasis↗
PubMed1984

Late wound complications after circular keratotomy for zoster keratitis.

We observed spontaneous melting and separation of circular keratotomy wounds in two zoster patients 8 and 23 years, respectively, after surgery. In one case, it could be demonstrated that the upper part of the unaffected keratotomy wound was formed by a large epithelial plug. It is probable that this type of wound may cause late complications under unfavorable conditions.

Adult↗
PubMed1983

[Allergic granuloma of the conjunctiva].

The authors describe clinical and histopathologic findings in three patients with so-called allergic granulomas of the conjunctiva. The subconjunctival, yellowish, quite sharply delineated nodules are caused by local precipitation of an antigen-antibody complex (Splendore-Hoeppli phenomenon) with a subsequent surrounding foreign body reaction. The granulomas may represent a reaction to parasites. In the authors cases, however, no etiologic factor could be identified.

Adolescent↗
PubMed1982

[Spontaneous healing of a cataract with secondary glaucoma (author's transl)].

A 55-year-old man was referred to our clinic with a mature, swollen cataractous lens and a secondary phakolytic glaucoma. However, the patient refused to undergo surgery. Twelve years later he returned. Meanwhile the lens had been almost completely absorbed; visual acuity was 20/32 and there had been no severe damage to the optic nerve. The speed of absorption of the lens had evidently been sufficient to cure the secondary glaucoma rapidly.

Adult↗