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Biomedical subjects

H Westling

Publications and source records attributed to H Westling.

At least 55 records · Page 3Linked to original sources
PubMed1976

A system for computer-assisted ECG recording at rest and exercise.

Great investments have been made in computerized ECG interpretation but little attention has been paid to rationalization of such costly activities as recording, labelling and mounting ECGs, and still less to the presentation of ECGs. A system for such tasks is described. It includes a PDP8/E computer and modified ink jet ECG recorders, which write alphanumeric text and function as analogue input- and output-devices for the computer. On-line computer service is given independently to two laboratories for ECG at rest, VCG or exercise ECG. After averaging the ECG signal, the computer writes out a properly labelled ECG in an easily surveyable form. The visual interpretation of the ECG is entered and is then written on a new sheet together with the averaged 12-lead ECG and a rhythm strip. In exercise testing, the computer records and processes the ECG at predetermined intervals. The processing includes an automatic ST classification. A summarized presentationof the ECG before, during and after exercise allows easy visual identification of ECG changes. Experience of the system has mainly been obtained from 2 years of routine exercise ECG recording and to a limited extent from ECG and VCG recording at rest.

Cardiology↗
PubMed1975

Effects of an antebrachial cimino-brescia arteriovenous fistula on the local circulation in the hand.

A female patient with a side-to-side fistula between the radial artery and the cephalic vein complained of pain in the three radial fingers during dialyses. Using 133-Xenon and histamine injected locally into the thumb musculature, local effective arterial pressure was found to be decreased, and to rise after compression of the fistula, or the radial artery distal to the fistula. The patient's symptoms thus were probably ischaemic and disappeared after ligation of the radial artery distal to the fistula. Ten more patients, of whom 9 had no local symptoms, were studied using the same technique. In 3, systolic blood pressure was measured in the thumb by a strain gauge technique. Some "steal" of thumb blood pressure by the fistula could be demonstrated in all patients but one and retrograde flow of blood in the artery distal to the fistula in 8. "Supernormal" Xenon wash-out occured when the pressure head was restored to normal by compression of the fistula or the radial artery distal to it. This is probably due to a compensatory increase of the distal vascular bed. The technique can be used for investigation of patients with suspected ischaemia distal to an arteriovenous fistula, and to indicate the appropriate treatment, usually ligation of the artery distal to the fistula.

Adult↗
PubMed1972

Histamine formation from 14 C-L-histidine in man.

1. (14)C-L-histidine was given i.v. to one normal subject and two patients with chronic myelocytic leukaemia. Urinary excretion of histamine and two of its metabolites methylhistamine and methylimidazoleacetic acid, total as well as (14)C-labelled, was measured, as well as blood (14)C-histamine. In addition the total urinary and pulmonary elimination of (14)C was followed.2. Total (14)C elimination was high during the first days, then declined slowly except for a plateau at the 10th-14th day in the two patients. There was a measurable elimination even after some months.3. (14)C-histamine appeared in the blood of the leukaemic patient, whereas in the normal subjects the values were hardly measurable.4. The leukaemic patients excreted much more of the two (14)C-labelled histamine metabolites than the normal subject. The difference in excretion of the (14)C-labelled metabolites was largest around the 12th day after the infusion of (14)C-L-histidine.5. The results indicate that the leukaemic patients formed at least 20 times more histamine daily than the normal subject.

Acetates↗