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Biomedical subjects

H Vosberg

Publications and source records attributed to H Vosberg.

At least 55 records · Page 3Linked to original sources

[Scintigraphic examinations of the lymph before endolymphatic radionuclide therapy of the malignant melanoma of the inferior extremity (author's transl)].

Between 1974 and March 1977, lymph scintigrams were taken on 68 patients with operated malignant melanomas of the inferior extremity before submitting these patients to an endolymphatic radionuclide therapy. The authors wanted to prove that the lymph canals were undamaged in order to avoid unnecessary cutaneous irradiation damages in case of a subsequent additional therapy. 58 lymph scintigrams showed normal findings with a symmetrical transport of 99mtechnetium-sulfur colloid into the inguinal and iliacal lymph nodes of both sides. The ELRT could be accomplished successfully on all patients of this group. Ten lymph scintigrams showed pathological findings with evidence of activity in the wound region. The ELRT was cancelled in eight cases, and two essays had to be stopped without any success. Our experiences show that lymph scintigraphy with 99mtechnetium-sulfur colloid is a simple and reliable method to examine the lymph canals of the inferior extremities. In case of patholological findings, one can avoid to order unnecessarily the expensive radioactive substance for the endolymphatic radionuclide therapy. An alternative punction point to that on the instep which is ordinarily used can possibly be found by a repeated examination.

Adult↗

[Isotope angiographic measurement of blood flow velocity in the human aorta and major arteries. I. Methodology and physiological considerations].

A special 8-channel detector arrangement was used to determine atraumatically the mean blood flow velocities in the aorta and the large arteries of the lower extremities in man. Following intravenous injection of 99mTc-pertechnetate time-activity curves were recorded over defined measuring points over the arteries, from these the appearance times of the tracer determined, and the mean blood flow velocities calculated from the differences between appearance times (the minimal transit times) and the distances between measuring points. The simultaneous determination of the minimal transit times between the vena cava inferior and the root of the aorta, which correspond closely to the total cardiac transit times, permits recognition of cases in whom blood flow velocity is reduced as a result of cardiac disease.

Adult↗

[Age-dependent changes of hypophysis-thyroid - regulation (author's transl)].

In health men and women different age total thyroxine, free thyroxine-binding-capacity, total triiodothyronine as well as TSH in serum before and after intravenous application of 500 mcg synthetic thyrothropine-releasing-hormone (TRH) were controlled. The investigations have shown: 1. With increasing age total thyroxine level in serum does not change. 2. With increasing age free thyroxine-binding-capacity in serum does not change. 3. With increasing age in men and women a significant decrease of total triiodothyronine in serum is to be measured. 4. Basal TSH serum levels do not change with increasing age. On the other hand in men and women with increasing age significant decreased TSH increments after TRH application were measured. The investigations have shown, that with increasing age the hypothalamus-hypophysial-thyroid-axis is shifting to a lower regulation level.

Adolescent↗