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Biomedical subjects

H Taguchi

Publications and source records attributed to H Taguchi.

At least 505 records · Page 28Linked to original sources
PubMed1983

[Clinical study concerning upper urinary tract obstruction. 2. Relationship between 99mTc-DMSA uptake in obstructed kidneys and their functions].

To establish a method of detecting divided renal function of the obstructed kidneys noninvasively, comparative studies on 99mTc -DMSA uptake (60 minutes after injection), I 131-hippuran renal uptake (1-2 minutes after injection) and divided creatinine clearance immediately after relief of urinary obstruction were made on 24 cases of obstructive uropathy. A close significant correlation was obtained between 99mTc -DMSA and I 131-hippuran renal uptakes (gamma = 0.8809, P less than 0.001). Also, a significant correlation was noted between 99mTc -DMSA renal uptake and divided creatinine clearance (gamma = 0.7876, P less than 0.001), but the latter constantly gave lower values than the former. These observations led us to conclude that 99mTc -DMSA renal uptake is a reliable indicator of the renal plasma flow in the obstructed kidneys. Quantitative divided renal function of the obstructed kidneys can be estimated by the 99mTc -DMSA uptake method.

Adolescent↗
PubMed1983

[Establishment and characterization of ATLV-producing cell lines].

Peripheral blood lymphocytes from a Japanese monkey (Macaca fuscata) were co-cultivated with lethally irradiated MT-2 cells that carry abundant type C virus particles (ATLV) isolated from a patient with adult T-cell leukemia (ATL). After six weeks, a lymphoid cell line designated Si-1 was established from the simian lymphocytes. The Si-1 line was E-, SIg-, Leu-1-, OKI1+, EBNA-, ATLA+ and ATLV+. Co-cultivation of peripheral blood lymphocytes from three anti-ATLA positive and two negative healthy adults resulted in the establishment of three lymphoid cell lines derived either from an anti-ATLA positive donor or both donors. All three cell lines were E+, SIg-, Leu-1+, OKI1+, EBNA-, ATLA+ and ATLV+. This mixed lymphocyte culture technique provides a simple means for the isolation of ATLV from healthy ATLV carriers.

Adult↗
PubMed1983

Three cases of pre-adult T-cell leukemia.

Three patients with pre-adult T-cell leukemia (ATL) are reported. All of them were seropositive to ATL-associated antigens (ATLA) and had 3-30% abnormal lymphocytes with cleaved or lobulated nuclei in the peripheral blood in the absence of clinical symptoms of ATL. All the data on immunological tests were normal except for negative purified protein derivative skin tests. In Case 1 the patient was an elder sister of an ATL patient. Four other members of this family were also anti-ATLA positive without abnormal cells in the blood. In Cases 1 and 2, ATLA and ATL virus (ATLV) were expressed in the lymphocytes cultured with phytohemagglutinin or T-cell growth factor. Moreover, an ATLV-producing cell line was established from Case 1 by mixed lymphocyte culture with lymphocytes obtained from a normal anti-ATLA negative person. Investigation of pre-ATL cases may clarify factors leading to the development of ATL in ATLV-infected persons.

Adult↗