Biomedical subjects
Publications and source records attributed to H Sugimoto.
Reported here are the lymphographic findings of a patient with toxopasmosis, which, though non-specific, aided in evaluating the effects of treatment. Toxoplasmosis should be included the differential diagnosis of patients with unexplained lymphadenopathy.
In 53 extensively burned patients, a comparative study was conducted on lactated Ringer's solution, colloid plus lactated Ringer's solution and hypertonic lactated saline solution on their hemodynamic and respiratory effects. The total amount of infusion required to resucitate the initial hypovolemic phase was the least in the hypertonic lactated saline solution group; whereas, the total sodium intake was the greatest in the lactated Ringer's solution group. Elevation of the respiratory index in the hypertonic lactated saline solution group was slightly more than the normal range, but insignificant. Cardiac output decreased initially in all three groups, but a hyperdynamic state with a simultaneous increase in the respiratory index occurred rapidly in the lactated Ringer's solution group; however, it occurred after five to seven days in the other two groups. Arteriovenous oxygen content difference increased in the hypertonic lactated saline solution group and decreased in the colloid plus lactaed Ringer's solution group, with no significant change in the lactated Ringer's solution group. From this study, the use of hypetonic lactated saline solution seems to be the best choice in the initial resuscitation of thermal injury.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The effects of S-methylmethionine sulfonium chloride (MMSC, vitamin U) on aminonucleoside-induced nephrotic hyperlipidemia in rats were investigated. We found that repeated oral administration of MMSC (dose: daily 1000 mg/kg) exhibited significant amelioration of plasma chloresterol and phospholipids levels. Also, the treatment improved nephrotic syndrome itself by producing an increase of urinary volume and a decrease of urinary protein excretion. The results suggest that MMSC may be useful as single or combined therapy for human nephrotic syndrome and its related hyperlipidemia as a safety drug.
In this paper, we show techniques to examine the stationarity and the normality of time series as well as results obtained by applying these techniques to EEG data during sleep stages. Many statistical analyses of the EEG data are based on the assumption that the EEG data are stationary and normally distributed. However, the problem is to know the length of data which is most appropriate for the statistical analysis. From the analysis, it is found that a decreased length of data implies an increased degree of stationarity and normality in each stage of sleep. However, for the practical stationary analysis of EEG data, it is shown that it is appropriate to take about 5 s during sleep state. Stationarity is fulfilled to a relatively large extent in REM but more seldom in stage 2. In the case of short data, asymmetric distribution occupies the large parts of non-normal distribution. As the length of data increases the proportion which is symmetric but sharper or flatter than the normal distribution increases.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Biomedical data, such as EEG, EMG and neural impulse sequences, are regarded as the stochastic phenomena of biological systems, and the statistical properties of such time series are often examined. Most of the statistical analysis processed in the frequency and the time domain are based on the assumption that the time series is weakly stationary and normally distributed. Therefore, as the basis of the statistical analysis of the biomedical data, it is necessary to know whether they satisfy the conditions of weak stationarity and normality. However, impulse response and evoked potential biomedical data, are not regarded as the stationary time series. Therefore, other analysis is required. In this paper, the authors present four programs, TEST1, TEST2, TEST3 and TEST4, to examine above conditions. Furthermore, in order to clarify the characteristic of each program, the time series were generated by the computer and examined by the test programs.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A 50-year-old woman was found to have an extramedullary plasmacytoma of the thoracic vertebrae and a bone marrow plasmacytosis of 72%. In the serum of this myeloma patient, M-bow percipitin line was seen only with anti-lambda chain serum, but not with antisera against mu, alpha, gamma, delta, ipsilon and kappa chains. Gel filtration of the serum on the Sephadex G-200 column demonstrated the monoclonal lambda chain in the A-fraction along with transferrin and suggests a molecular weight of 88,000 and a tetrameric light chain. Bence-Jones protein has never been detected in the patient's urine.
Explore the source record for details and available documents.