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Biomedical subjects

H Stickl

Publications and source records attributed to H Stickl.

At least 37 records · Page 2Linked to original sources

[Travel diarrhea].

The most important means to stop diarrhea, especially in travellers in subtropic and tropic areas, is the ample supply of lost electrolytes and water. In most cases no further treatment will be necessary. The oral substitution of enough fluid, glucose and electrolytes is described.

Diarrhea

Specificity of antibody-dependent lymphocyte cytotoxicity against cerebral tissue constituents in multiple sclerosis. Studies with basic protein of myelin, encephalitogenic peptide, cerebrosides and gangliosides.

In patients with multiple sclerosis (MS) there is not only an antibody-dependent lymphocyte cytotoxicity (ADLC) against basic protein of myelin (MBP), as was demonstrated earlier, but also against encephalitogenic peptide, cerebrosides and gangliosides. The reaction against cerebrosides and gangliosides is not specific for MS; it is also frequently positive in patients with other neurological diseases (OND), syphilis and rheumatoid arthritis. The ADLC against encephalitogenic peptide shows a very high specificity for MS. Out of 35 cases with OND, 23 had a positive result with MBP, but only one with encephalitogenic peptide. Patients with syphilis and rheumatoid arthritis reacted negatively without exception. According to this, the encephalitogenic peptide is a highly specific antigen for MS; MBP shows less specificity. The ADLC against the encephalitogenic peptide shows a markedly increased sensitivity in MS compared with MBP. Specificity and frequency of positive findings with encephalitogenic peptide support the pathogenic significance of the reaction in MS.

Adult

[Recurrent facial herpes simplex. Treatment with active paramunization].

132 patients with herpes simplex manifestations were treated with PIND, a heterologous pox-virus-antigen, that stimulates T-cells and macrophages. The shortening of duration of the disease, the subsequent relief from pain and the decrease in frequency of recurrence was proven.

Adjuvants, Immunologic

[The influence of the environment on the human immune system].

Different conditions in the human biotop and behavior are investigated and described regarding their influence on resistance and immune reactions: There is a big variety of interactions between the human biotop and immune reactions. Knowing the correlations and the dependences between both, it should be possible to arrive at a new level of optimations in human live.

Antibody Formation

[Unspecific vaccination].

All vaccines have--besides their specific effect on the immune response--more or less pronounced side effects on the organism and particularly on the immune system. The latter effects deserve special interest, whenever they increase the host defence against infectious diseases. Desirable paraspecific effects of vaccines are the induction of interferon, the enhancement of phagocytic function and the activation of lysosomal enzymes. Some vaccines exert different effects: attenuated live measles vaccine induces interferon, pertussis vaccine activates lysosomal enzymes of macrophages. Some clinical observations illustrate how paraspecific effects of vaccines can be utilized for therapeutic purposes.

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