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Biomedical subjects

H Spinnler

Publications and source records attributed to H Spinnler.

131 records · Page 8Linked to original sources
PubMedDate not supplied

[Natural history, treatment and outcome of cerebellar softening (author's transl)].

21 adults with acute cerebellar softening were divided into two groups. In the first group (6 patients) the clinical course was progressive with deterioration of consciousness, signs of brain-stem compression and some degree of enlargement of ventricles (CT scan). Of these patients, three were treated surgically with success, one recovered spontaneously and two others died post-operatively. In the second group (15 patients) the course was much more favourable. Without surgery the cerebellar symptoms and signs improved, in spite of the persistence of discrete cerebellar signs one month after the onset of symptoms. Medical and/or surgical treatment of the disease are discussed, including the differential diagnostic aspects as well as the CT scan features.

Cerebellar Diseases↗
PubMedDate not supplied

[Outcome of Parkinsonism after two years of levodopa plus R04-4602 (author's transl)].

Twenty-one patients suffering from Parkinson disease were treated with L-Dopa together with an extra-cerebral dopa-decarboxylase inhibitor (Ro4-4602) and with triesyphenidyl. Seven assessments of the patient's clinical condition were carried out over a period of two years with a number of neurological and psychometric tests. At the beginning of the second year of treatment, the signs and symptoms of Parkinson disease began to worsen with an increased disability. In the present paper two possibilities are discussed, namely whether the deterioration was the consequence of L-Dopa administration or whether this was simply the outcome of inadequacy of drug treatment during a period of natural worsening of the disease.

Adult↗