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Biomedical subjects

H Singh

Publications and source records attributed to H Singh.

At least 793 records · Page 44Linked to original sources
PubMedDate not supplied

Investigation of Erythrina spp. VII. Chemical constituents of Erythrina variegata var. orientalis bark.

The petroleum ether extractive of the bark of Erythrina variegata var. orientalis was fractionated and shown to be composed of wax alcohols and wax acids, alkyl ferulates, alkyl phenolates, stigmasterol, sitosterol, campesterol and possibly citrostadienol/24-methylenelophenol. The ethanol extractive yielded chloroform-soluble and water-soluble bases, identified as erysovine and stachydrine, respectively.

Cinnamates↗
PubMedDate not supplied

Hepatitis B and C virus--prevalence and prevention in health care workers.

BACKGROUND: Hepatitis B and C viruses are important causes of liver related morbidity and mortality. We aimed at determining the presence of hepatitis B and C virus infections in the health care workers (HCWs) and their compliance for the HBV vaccination. METHODS: Three thousand five hundred and fifty six health care workers were screened for HBsAg and 115 for anti-HCV by ELISA. HBsAg negative individual were offered HBV vaccination and record of their compliance was kept. Anti-HBs titers were determined one month after 2nd or 3rd dose of vaccine in 273 subjects. RESULTS: Out of 3556 health care workers, 61 (1.7%) were found to be positive for HBsAg. One out of 115 HCWs (0.87%) was found to be positive for anti-HCV. Fifteen percent of HCWs received only one dose, 26% received two doses 59% received three doses and 2.5% also received the booster dose of the HBV vaccine. All those tested had anti-HBs titers more than 10 mUI/ml. CONCLUSION: In HCWs, HBsAg and anti-HCV prevalence was found to be 1.7% and 0.87% respectively. HCWs in our hospital, despite the awareness on HBV and HCV infection are noncompliant for HBV vaccination.

Adult↗
PubMedDate not supplied

Evaluation of decalcified allogenic bone matrix grafts in and around root apices. A histological study.

Decalcified Allogenic Bone grafts were implanted in and around eighteen root apices after apicoectomy. The procedure was carried out on eighteen rabbits, dividing them into three groups of six rabbits each. The animals were sacrificed after 48-72 hours, 8-10 days & 8-10 weeks period of interval. Result of the present investigation reveal that DABM grafts stimulate osteogenesis and cementogenesis after the initial phase of inflammation. Tissues simulating bone and cementum appear at the apical end, speculating that the grafts would certainly result in physiological sealing of root apices. The possibility of saving the life of non vital teeth with or without wide apical foramen will enhance in future.

Animals↗
PubMedDate not supplied

Complete A-V block and phrenic paralysis complicating surgical closure of ventricular septal defect--a case report.

The incidence of post-surgical complete A-V block has come down from 16% in the 50's to less than 1% with improvement in technique. Of these, 14% are transient and attributable to post-operative oedema and haemorrhage at the site of block. Permanent damage manifests early, or as late as 15 years, and in these, the risk of sudden death is a reality. Phrenic paralysis has been attributed to inadvertent pinching, cutting, traction on the phrenic nerve, and has been noticed after pericardiectomy, Blalock-Hanlon operation, Mustard repair, performance of a Blalock-Taussig shunt or closure of ASD. It has also been noted to result from hypothermic injury following iced saline slush application for topical hypothermia the so called "Frost Bitten Phrenics". The entity is commoner than appreciated, although its actual incidence has not been properly worked out. It can be unilateral or bilateral. Patients are mostly asymptomatic, the post-operative X-Ray chest revealing the defect. Uninhibited movement of the costal margin away from the midline on the side of paralysis gives clinical clue (Hoover's Sign), and is confirmed by fluoroscopy which shows paradoxic diaphragmatic movement on sudden sniffing (Keinbock's Phenomenon).

Child↗
PubMedDate not supplied

Comparative efficacy of atenolol and labetalol in essential hypertension--a double blind cross over trial.

In a double blind cross-over drug trial, antihypertensive effects (resting and after dynamic exercise) of atenolol and of labetalol were studied in 20 patients of mild to moderate essential hypertension. Both drugs exhibited almost equal antihypertensive response, and were well tolerated. Haemodynamic variables (HR, SBP, DBP and RPP), both at rest and after maximal tread mill exercise, were significantly altered (P less than 0.001) by both drugs. Exercise capacity was observed to be marginally improved by atenolol. Although the antihypertensive effect, when compared between the two drugs, was not statistically significant, individual suitability or comparison revealed a preference for atenolol in 17 patients and for labetalol in 3 patients.

Adult↗