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Biomedical subjects

H Seki

Publications and source records attributed to H Seki.

At least 343 records · Page 19Linked to original sources
PubMed1979

[Production of infarction model in dogs by several brain arteries occlusion. Part 1: Production of hemispheric non blood supply model (author's transl)].

Experimental brain infarction in model animals should most ideally be constant in the site of occurrence, be of severity that is controllable by the occlusion time of blood flow and, moreover, be reproducible at a high rate to desired extent and severity. However, among infarction models elaborated in animals so far, only thalamus infarction model in dogs which were reported by us previously have been proven to satisfy almost all of these requirements. In experiments with these model dogs we found that an extensive infarction can be produced at a high frequency in the involved hemisphere by a transient occlusion of blood flow at such intracranial levels as the internal carotid artery, the junction of the anterior cerebral artery and ophthalmic artery, the middle cerebral artery, the origin of the segment A2 of the anterior cerebral artery, and the junction of the posterior communicating artery and posterior cerebral artery. During about one hour following the releasing of the arteries approximately 2 hours occlusion, the development of severe brain edema resulted involving the whole hemisphere on the affected side invariably in all cases. This method for experimental production of brain infarction permits to control the degree of resultant brain edema by changing the duration of occlusion of blood flow, requires simple manipulations only and ensures production of a constant lesion. With these advantage it can be anticipated to prove of great benefit in the study of postischemic brain edema.

Animals↗
PubMed1978

[The relationship between the rupturing of intracranial aneurysm and season, weather and patient's acitivity (author's transl)].

Some physical and mental stresses have been notices as the exciting factors for the occurrence of cerebrovascular diseases. However, little has been known about them of ruptured intracranial aneurysms. From this point of view, the correlation between the several physical strains and the occurrence of ruptured intracranial aneurysm were studied in this report. This study was based on 920 cases of ruptured intracranial saccular aneurysm which were verified by direct aneurysmal surgery. As for the season, the occurrence of ruptured intracranial aneurysms was apt to be frequent in winter and infrequent in summer. No relation between the onsets and the meteorological fronts could be found. The incidence during sleep was about 6%. This incidence was thought to be rather lower considering the fact that one-third of our lives is spent in sleep. Lifting and bending, defecation and/or urination and emotional strain were among the commonest environmental events associated with the onset. Based on these results, wheather or season, which is mild physical stress, can in no way be considered a great cause of rupturing of intracranial aneurysm, but it should seen that patient's activities or events have some influences in rupturing of aneurysm to a great extent.

Humans↗
PubMed1977

Endoscopic retrograde cholangiopancreatography (ERCP) performed in children.

The value of ERCP in children is demonstrated on 3 cases. By using a usual duodenofiberscope (JF-B2), in 2 cases under general anesthesia and in one case after premedication with 1 ml Buscopan i.m., a similar technique is used as in adults. In congenital choledochal cyst only ERCP allowed the exact judgement of the distal part of the common bile duct and its relation to the pancreatic duct. Therefore, an exact preoperative diagnosis can be established. When duodenofiberscope will be more improved ERCP will also be possible in the newborn infant. Than the differential diagnosis of congenital biliary atresia, other congenital failures in infants causing jaundice and hepatitis in infant will be established endoscopically.

Adolescent↗
PubMed1977

Distribution of HLA-B27 in patients with juvenile rheumatoid arthritis.

HLA antigens were examined in 27 patients with juvenile rheumatoid arthritis. HLA-B27 was found in none. The result was different from most other previously reported studies. The most likely explanation for this difference is the possibility that some patients with juvenile ankylosing spondylitis may have been included among the patients in the other studies.

Adolescent↗
PubMed1977

The anterior and the posterior longitudinal ligaments of the lower cervical spine.

The anterior and the posterior longitudinal ligaments (ALL and PLL) of the cervical spine were examined. The ALL and the deep layer of the PLL are continuous, and surround the vertebral body. The superficisl layer of the PLL surrounds the dura mater, nerve roots and the vertebral artery, suggesting that this membrane may serve as a protective membrane for the soft tissues inside the vertebral canal rather than as a conventional ligament.

Adolescent↗