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Biomedical subjects

H Schramm

Publications and source records attributed to H Schramm.

At least 73 records · Page 4Linked to original sources
PubMed1981

[Roentgenologic and endoscopic findings after papillotomy].

During 1977--1980 36 papillotomies were performed; indications for the latter were: papillary stenosis, incarcerated stones or stones which could not be removed which certainty and suspicion of a papillocarcinoma. The indications were evaluated as to whether endoscopic or surgical papillotomy should be performed. The results of the papilloplasties were considered satisfactory. In 40% of the cases a duodenobiliary reflux was observed, which however did not give troubles.

Adult↗
PubMed1981

[Early and late results of internal small intestine splinting for ileus].

The continuous inside splinting of the small intestine was carried out in 82 children and adults, because of postoperative ileus, chronic recurrent ileus and diffuse peritonitis. Possibly the splinting had contributed in one case to the perforation of the paralytic small intestine with a fatal outcome. In another case there occurred a relapse of an ileus. All other patients have no complaints in connexion with the splinting operation. Control examinations take place. A "total folding" of the small intestine was not observed by the radioscopy.

Adult↗
PubMed1980

[Surgical therapeutic concept in peptic jejunal ulcers (author's transl)].

It is reported about 79 repeated interventions because of an ulcer pepticum jejuni and its relapses. The high rate of relapses to about 30 percent even after repeated interventions requires a radical concept of the reduction of acid. If a subsequent resection is necessary vagotomy should always be carried through, if possible in form of a selective vagotomy, vagotomy alone in case of a not penetrating flat ulcer or small residue of the stomach. If the general somatic condition of the patient allows it, duodenal passage should be carried through by means of the jejunal interposition. The examinations of the preoperative secretion have their greatest value in finding extragastric acid stimulators or antrum residues left behind.

Adult↗
PubMed1979

[Toxic megacolon in Crohn's disease (author's transl)].

The toxic megacolon is well known in colitis ulcerosa, in colitis ulcerosa, in colitis granulomatosa--Crohn's disease--it is by far rarer. The authors observed two cases among their patients. The emergency operation consisted in applying an ileostoma and several colostomata. The definitive treatment with colectomy and ileorectostomy was done after weeks respectively months.

Adult↗
PubMed1977

Regulation of glycogen synthetase and phosphorylase phosphatase activities in rat adipose tissue.

Incubation of a rat adipose tissue homogenate causes a time and temperature dependent activation of glycogen synthetase (UDP glucose:glycogen 4-alpha-glucosyltransferase) and simultaneous inactivation of phosphorylase (1,4-alpha-D-glucan: orthophosphate alpha-glucosyltransferase, EC 2.4.1.1). Activation of glycogen synthetase at 15 and 23 degrees C was preceded by a lag period. The duration of the lag period could not be correlated with significant changes in phosphorylase activity. Addition of glucose and methylxanthines caused an increase in the rates of glycogen synthetase activation and phosphorylase inactivation. The effect on glycogen synthetase activation was mainly on the linear phase. Addition of AMP inhibited phosphorylase inactivation and accelerated glycogen synthetase activation. Addition of muscle phosphorylase alpha caused a prolongation of the lag period which lasted until phosphorylase alpha activity had decreased to the level originally present in the preparation. It is concluded that in adipose tissue activation of glycogen synthetase is not dependent on prior inactivation of phosphorylase and that other factors should be looked for to explain the lag period preceding glycogen synthetase activation.

Adenosine Monophosphate↗
PubMed1977

[Effect of bilateral and unilateral vagal stimulation of gastric acid production in the rat].

In experiments on rats the anterior or/and the posterior gastric vagus nerve were electrically stimulated. The extent and site of acid-producing gastric areas were demonstrated by help of Congo red. Unilateral stimulation resulted in enhanced acid secretion in a smaller area of gastric mucosa. The acid-secreting areas showed no different distribution at stimulation of the anterior or posterior vagus nerve.

Animals↗
PubMed1977

[The effect of pyloric stenosis on the development of stress ulcers in the rat].

The authors examined in rats the importance of pyloric stenosis for the development of spontaneous acute ulcers and stress ulcers in the stomach. Spontaneous superficial lesions arise only during the first 20 days. They apparently signify an intensified narrowing by postoperative swelling with mechanical stimulation of gastrin secretion in the antrum. They were not observed during later periods. Chronic ulcers did not develop. Stress ulcers caused by immobilization were more frequently seen in rats with pyloric narrowing than without. Vagotomy protected the rats with pyloric stenosis from stress ulcer, although not as certain as in control animals.

Animals↗
PubMed1976

[Incidence of stress ulcer and secretion of gastric juice following truncal and selective vagotomy].

In rats development of stress ulcers by immobilization is accompanied by elevated pH, reduced amount of gastric juice, and by this with decreased amount of acid. Consequently, the acid factor has no primary importance for the development of stress ulcer. Truncal vagotomy, selective proximal vagotomy, and selective antral vagotomy result in reducing the acid secretion at elevated pH value and increased juice amount, and in a decreased ulcer rate. Greatest certainty to prevent stress ulcer gives the truncal vagotomy, whereas there is a poor effect after antral vagotomy.

Animals↗
PubMed1976

[Role of the antrum in the etiology of stress ulcers in the rat].

In rats, antrectomy results in a decrease of ulcer rate by immobilization without statistic significance. Stress ulcer rate is also lowered by antral vagotomy, with statistically significant decrease of acid production. By antrectomy as well as by antral vagotomy just the acid production but not the circulatory disturbance in the mucosa of corpus is influenced, which is primarily responsible for the development of stress ulcers. This fact gives an explantation for the relatively high ulcer rate, compared with the conduction in rats after truncal vagotomy. Unclear remains whether antrectomy with consecutive total gastrin elimination is merely working by inhibiting the secretion, or if gastrin has a circulatory effect too.

Animals↗