[Actual state survey of the use of radioisotope instruments in Japan (author's transl)].
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Biomedical subjects
Publications and source records attributed to H Sawa.
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In patients with essential hypertension, a variation in the plasma proteins was revealed by high-resolution sodium dodecyl sulphate polyacrylamide gel electrophoresis. This variation in plasma protein was not found in patients with hypertension secondary to renovascular or renal parenchymal disease.
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We present an unusual case of a cervical thymoma arising from an undescended thymus, which showed a remarkable accumulation of Thallium-201 Chloride on scintigraphy.
A case of operatively proven congenital hepatic fibrosis was studied by scintigraphy with Tc-99m-phytate and Tc-99m-Pl (a hepatobiliary radiopharmaceutical). Two focal defects were recognized in the liver on the colloid liver scintigram. Ultrasound and contrast angiography suggested that the two focal defects were cystic lesions. Radionuclide hepatobiliary imaging was performed with Tc-99m-Pl, since intravenous cholangiography was unsatisfactory. One focal defect was proved to be a dilated intrahepatic bile duct and another was found to be cyst. Radionuclide hepatobiliary imaging with Tc-99m-Pl proved to be very useful in identifying dilated intrahepatic bile ducts in this patient as well as in following the progress of this disease.
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Forty-two arterial blood pH and gas determinations were carried out on 11 patients with fulminant hepatic failure. The most common type of acid-base disturbance was that of respiratory alkalosis in 22 cases (52.4%). This was partially compensated in 13 subjects (31.0%) while an accompanying metabolic alkalosis was present in 9 (21.5%). Partially compensated metabolic acidosis was observed on 15 occasions (35.7%), all of which were in patients with laboratory evidence of impaired renal failure. The mental status of the patients was evaluated in each of the categories of acid-base disturbances. Some degree of correlation was evident between the PCO2 and the magnitude of base excess and that of the severity of the encephalopathy. The lower PCO2 and greater negative base excess values tended to be nearly always present in totally comatose subjects. By contrast, there was no clear cut relationship between pH and mental state.
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