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Biomedical subjects

H Savir

Publications and source records attributed to H Savir.

At least 73 records · Page 4Linked to original sources
PubMed1983

Presenile cataracts in phenytoin-treated epileptic patients.

Cataracts developed in two young adults who were receiving prolonged antiepileptic treatment with phenobarbital sodium and phenytoin sodium. The known side effects of these drugs are serious and varied, and phenytoin is strongly implicated in the etiology of cataracts in human beings. Results of our research study on rats supported our view on the cataractogenic action of phenytoin.

Adult↗
PubMed1983

Scleral perforation during cataract surgery.

Two cases are described of scleral perforation due to the needle of the bridle suture done before cataract extraction in 1,280 consecutive cases. The immediate diagnosis is important and is based on acute hypotony of the globe, the appearance of vitreous fluid under the conjunctiva, or both. Cryopexy with scleral buckling followed immediately by the usual cataract extraction is recommended. This procedure allows judgment of the actual state and avoids a second operation.

Aged↗
PubMed1983

Presenile cataracts in hydantoin-treated epileptic patients.

Two young epileptic adults developed cataracts resembling presenile diabetic lens changes, while on prolonged antiepileptic treatment with phenobarbitone and diphenylhydantoin (DPH). A research study on rats supported our view on the cataractogenic action of DPH.

Adult↗
PubMed1982

Evaluation of laser iridectomy in angle-closure glaucoma: provocative tests.

An argon laser iridectomy was performed on 18 eyes of 14 patients with closed-angle glaucoma. The intraocular pressure (IOP) was controlled in all but one eye within normal limits. Variable amounts of pigment were found on gonioscopy in all cases. The mydriasis test was positive in one eye (5.5%) after homatropine and in 5 eyes (28%) after tropicamide drops. 80% of the positive results occurred in lightly pigmented irides. The dark-prone position test was positive in 7 eyes (38%), 71% of the positive results occurring in heavily pigmented irides. Tomography was also performed; the possibility of trabecular damage is discussed.

Eye Color↗
PubMed1982

Review of anterior chamber bleeding after cataract extraction in diabetic patients with and without Premarin treatment.

Three groups of 30 patients each were studied for frequency and severity of anterior chamber bleeding up to 5 days postcataract extraction. One group consisted of diabetic patients receiving Premarin treatment, one group of diabetics without Premarin treatment, and the third of nondiabetic patients. There seems to be less bleeding frequency and especially less bleeding severity in Premarin-treated diabetic patients.

Cataract Extraction↗
PubMed1981

Clinical trial of bromhexine in Sjögren's syndrome.

Tear secretion and lysozyme tear content were measured in 30 patients with Sjögren's syndrome after treatment with oral bromhexine, 32 mg/day. In 21 patients (70%) there was a marked increase in tear secretion and in lysozyme content. In patients with keratoconjunctivitis sicca (KCS) good results in clarifying the mucoid eye discharge were obtained. A remarkable amelioration of xerostomia was also noted. Six other patients, serving as controls, were given a placebo and bromhexine. The placebo had no influence on the rate of tear secretion, while bromhexine caused it to increase in 70% of the controls. This side effects of bromhexine treatment encountered in the present study were negligible and transient. We consider bromhexine to be the drug of choice in the treatment of Sjögren's syndrome.

Bromhexine↗
PubMed1980

Herpes virus hominis encephalomyelitis and retinal vasculitis in adults.

The cases of two adults who developed viral encephalomyelitis are presented. The diagnosis of herpes virus hominis infection was made as a result of the rising titers of herpes virus on indirect fluorescence tests in the serum and the cerebrospinal fluid. Both patients developed retinal vasculitis with retinal edema and hemorrhages. The importance of follow-up examinations of the fundus is stressed to avoid rhegmatogenous retinal detachment caused by retinal tears.

Aged↗