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Biomedical subjects

H Reich

Publications and source records attributed to H Reich.

At least 127 records · Page 7Linked to original sources

Synthesis and analytical use of 3-carboxypropionyl-alanyl-alanyl-valine-4-nitroanilide: a specific substrate for human leukocyte elastase.

A simple synthesis is described for 3-carboxypropionyl-Ala-Ala-Val-4-nitroanilide, a convenient and very specific substrate for human leukocyte elastase (Km = 1.0mM, kcat = 8.7 s-1). The substrate does not undergo appreciable spontaneous hydrolysis. It is not cleaved by trypsin or chymotrypsin and only rather slowly by porcine pancreatic elastase (Km = 9.1mM, kcat = 1.4 s-1).

Humans↗

[Ichthyosis].

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Adolescent↗

Choice of the measuring quantity for therapy-level dosemeters.

With the introduction of SI units in radiology the quantity exposure will probably be abandoned for therapy level dosemeters because of the inconvenient conversion factors which have, in SI units, to be applied for the change into absorbed dose. Instead of exposure, a quantity is envisaged which, like absorbed dose, is measured in the unit gray (= joule per kilogram). A difficulty lies in the fact that in the immediate future only primary standards of exposure will be available, necessitating the introduction of conversion factors at the interface between primary and secondary standards or field instruments. Expert opinion differs as to whether a kerma quantity, a half-way stage to the desired situation, should be used, or whether the full step should be taken involving the calibration of field instruments in terms of 'absorbed dose in water under specified conditions'. This paper discusses the problem and recommends the full step.

Radiometry↗

Computerized tomography in acute hemorrhagic leukoencephalopathy: a case report.

Computerized tomography in a case of acute hemorrhagic leukoencephalopathy showed extensive bilateral white matter damage, which resolved almost completely. The patient's near-complete recovery from the disease is followed by serial CT scans, suggesting that initial bilateral demyelinization is followed by slow remyelinization rather than disappearance of edema. CT scanning proves to be useful in the diagnosis and follow-up of white matter diseases.

Acute Disease↗

[The aging skin (author's transl)].

Aging of the skin appears in circumscribed as well as in generalized forms. The localized alterations may be subdivided in such of inflammatory origin and in hyperplastic ones. The latter include benign and also precancerous tumors. The generalized and usually premature manifestations of cutaneous senescence are almost always part of some hereditary disease which frequently also affects the viscera, sense organs, skeleton, and the nervous system.

Aged↗

[Successful zinc treatment of a severe case of acrodermatitis enteropathica (author's tteropathica].

A 24-year-old patient treated with hydroxychinoline preparations without cure for acrodermatitis enteropathica since he was nine years old was given zinc oxide orally, at first 50 mg three times, later twice daily. Zinc concentrations in blood plasma, whole blood and sputum were serially determined. At the start of treatment they were significantly below that in four healthy controls. One week after starting zinc therapy the blood level had returned to normal and with it the changes in skin, hair and nails had regressed, as had the emotional disturbances.

Acrodermatitis↗

[Acrodermatitis enteropathica--zinc as a life-saving drug].

Formerly acrodermatitis enteropathica was treated with oxiquinoline without full control of the disease and with the danger of blindness. Moynahan has introduced zinc into the treatment with excellent results, based on the finding that acrodermatitis enteropathica is a zinc-deficiency disorder. Other authors and own observations have confirmed the findings of Moynahan. There are clinical, genetical, immunological and therapeutical parallels between the acrodermatitis enteropathica of man and the so-called hereditary parakeratosis of calves which also is a hereditary disturbance of zinc metabolism. The treatment of acrodermatitis enteropathica with zinc is furthermore a great success in the prevention of blindness, as zinc is not dangerous to the retina and the optic nerve.

Acrodermatitis↗