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Biomedical subjects

H Pristautz

Publications and source records attributed to H Pristautz.

At least 55 records · Page 3Linked to original sources
PubMed1981

[Clinical evaluation of serum bile acids as a new liver function test (author's transl)].

In a randomized patient material, with various histologically verified hepatobiliary diseases, the serum levels of Cholyl glycine (CG) and Sulfolithocholyl glycine (SLCG) were compared with each other. SLCG levels are a more sensitive parameter and permit a more significant differentiation between fatty and normal livers and between cases with and without portal hypertension in liver cirrhosis. There were poor correlations between the hitherto routinely performed laboratory tests and the SLCG levels, but good correlations between SLCG and defined parenchymal liver diseases. the publication ends with the presentation of a newly developed SLCG-stimulation test, which provides a staging of parenchymal liver diseases without unnecessary requirements of time and material and with minimal stress to the patients.

Diagnosis, Differential↗
PubMed1980

[Influence of a highly purified D-thyroxine medication on thyroid iodine uptake and in vitro tests of thyroid function (author's transl)].

25 euthyroidal patients with elevated serum cholesterol levels were treated with 4 mg of D-thyroxine daily for 4 weeks; controls were made after this period and after a withdrawal period of another 4 weeks. At the end of the treatment period there was a significant decrease of the serum cholesterol level, of the basal and TRH-stimulated serum TSH and of the thyroidal radioiodine uptake. The radioimmunologically determined values of total T 3 and Free Thyroxine index and of the serum iodine level rose significantly without being accompanied by clinical hyperthyroid symptoms. These changes can be explained on one hand by the well known cholesterol lowering effect of D T-4 and by the inclusion of D-isomeres of thyroid hormones in the radioimmunoassay, and, on the other hand, by the fact that the above-mentioned medication causes an uptake of iodine, and, possibly, by a direct inhibitory effect of D T-4 on the pituitary gland.

Adult↗
PubMed1980

[Virus hepatitis B in hemodialysis wards: ways of distribution and possibilities of their interruption (author's transl)].

An attempt was made to describe differentiated problems in connection with virus hepatitis B in hemodialysis wards in a form as brief and precise as possible and to present some suggestions as to the elimination of this insidious disease. A through consideration of the hepatitis question yielding to a well established and legally sanctioned prevention concept would not only be of great importance to hemodialysis patients and their family members and the dialyses personnel but it would also play a great role for the protection of the general population. Finally, a statement by Baruch Blumberg (Nobel Price winner in Medicine, 1976) should visualize the universal importance of the hepatitis question once more: "If we succeeded in bringing hepatitis B under control, this would bring about a reduction of the rate of chronic liver diseases and of primary liver carcinoma."

Austria↗
PubMed1980

[Social profile and accompanying diseases in acute and chronic pancreatitis (author's transl)].

200 patients with pancreatitis were examined for various concomitant and previous diseases, and socioeconomic factors, in a retrospective study. This pancreatitis group (PG) was compared with a control group (CG) of 250 patients. Most frequent amongst the etiological factors, were biliary diseases, especially a state after cholecystectomy. Second in rank, was chronic alcoholism. For women, the incidence was highest in the 7th decade; for men, there was a double peak in the 4th and 6th decade, respectively. The incidence was about equal for both sexes. The following factors were found to play no essential role in the PG: type of profession, cigarette consumption, gastric and/or duodenal ulcers, partial gastric resection, renal and cardiac insufficiency, viral hepatitis, liver cirrhosis of hypertriglyceridemia. There is a significant accumulation of mumps in the history of the PG, which had gone along without any clinically detectable affection of the pancreas in childhood, in practically all cases.

Acute Disease↗
PubMed1979

[The influence of a beta-adrenolytic premedication on cardiovascular parameters and plasma free fatty acids during esophago-gastro-duodenoscopy (author's transl)].

Three groups of patients with different premedications were examined for changes of blood pressure, heart rate, ECG and plasma free fatty acid levels during esophago-gastro-duodenoscopy: Group A was premedicated with Bunitrolol, group B was premedicated with Hyoscin-N-butyl-bromide and diazepam, group C was endoscopied without premedication. The pulse rate rose significantly less in group A than in groups A and C; the same phenomenon was observed with regard to the systolic blood pressure. Premature beats occurred in all 3 groups: 32 per cent of the patients in group A, 43 per cent in group B and 60 per cent in group C had at least occasional premature beats; an accumulation of premature beats however occurred significantly less frequently in group A than in groups B or C. A drop of the ST-part of the ECG occurred with about the same frequency in each group. An increase of the plasma free fatty acids, which was noted in groups B and C, could be observed in Group A. A pre-endoscopic medication of beta blocking agents could be a useful measure in patients with labile arterial hypertension, vegatative dysregulation and a hyperkinetic heart syndrome.

Adrenergic beta-Antagonists↗
PubMed1979

[Early diagnosis of cancer of colorectal carcinoma by rectosigmoidoscopy (author's transl)].

The colorectal cancers in greater part grow out of polyps, which can be looked upon as optional precancerosis. Own results together with literature-reports show a distinct increase of the frequency of polyps beyond the age of fortyfive. The only digital palpation of the rectum is insufficient; it leads to the diagnosis of a rectum polyp only in 15.5%, to the diagnosis of a cancer in 13% of cases. With the rectosigmoidoscopy however the diagnosis is successful in 70% of cases. The percentage of precancerous polypous alterations detected by rectosigmoidoscopy is approximately the same in medical check-up as in directed examinations of patients with anorectal discomfort. A restriction of rectosigmoidoscopy to the last-named group of persons is not any longer justified. The polypectomy in the rectum is a real cancer-prevention.

Adenocarcinoma↗
PubMed1978

[Examination of cardiovascular parameters and plasma free fatty acids during esophago-gastro-duodenoscopy (author's transl)].

53 patients were examined for changes of blood pressure, heart rate, ECG and plasma free fatty acids during esophago-gastro-duodenoscopy. In 23 cases there were premature contractions, occuring in small numbers only in most of the cases. Only in 5 cases there was an accumulation of premature contractions and in one case ventricular bigeminism occurred. The maximum of premature beats was observed when the primarily sitting patient was put into supine position. In 7 patients there was a lowering of the ST-segment in the ECG by at least 0.1 mV, mostly in patients who already had an abnormal ST-segment before endoscopy. The pulse rate went up by an average of 50.1 per cent, the systolic blood pressure by 14 and the diastolic blood pressure by 17 per cent. The increase of plasma free fatty acids in the total patient material was not statistically significant, but patients with a deterioration of ECG-findings endoscopy had a significantly higher increase of plasma free fatty acids. There was a tendency towards a positive correlation between the number of premature beats and the increase of plasma free fatty acids. It cannot be decided from our study whether the mobilization of free fatty acids is causing the above observed increase of premature beats or whether both phenomena are merely a result of sympathetic nervous stimulation. Gastric fiberoscopy may be applied to elderly patients with decreased cardiac function. The endoscopic procedure should not be started on the sitting patient but primarily in left supine position.

Adult↗
PubMed1977

[The serum triglycerides and their role as a coronary risk factor (author's transl)].

291 patients with various types of hyperlipoproteinemia and 216 persons with normal serum lipid levels were examined for the frequency of angina pectoris and myocardial infarction. As a risk factor of myocardial infarction, Fredrickson's Type IIb was ranking on top, followed by simultaneous elevation of serum cholesterol and serum triglycerides regardless of the lipid-electrophoretic tappern, followed by Fredrickson's Type IV and finally by isolated hypercholesterolemia and Fredrickson's Type IIa. For angina pectoris, the order was slightly different: the highest risk factor was the simultaneous elevation of serum cholesterol and serum triglycerides, followed by hyperlipoproteinemia Type IV, hyperlipoproteinemia Type IIb, and finally by isolated hypercholesterolemia. The risk of both myocardial infarction and angina pectoris caused by isolated hypertriglycerolemia was not statistically significant, the same observation was made for the risk of angina pectoris in hyperlipoproteinemia Tye IIa. The present results confirm that an elevation of the serum triglycerides plays a minor role as a coronary risk factor in comparison to hypercholesterolemia.

Angina Pectoris↗
PubMed1977

[Pharmacokinetics of a combination of magnesium-chlorophenoxy-isobutyrate and meso-inositol hexanicotinate].

The absorption, blood level and renal excretion of chlorphenoxyisobutyric acid (clofibric acid) were examined following oral dosage of the magnesium salt (magnesium clofibrate) in a combination preparation containing meso-inositol hexanicotinate. Absorption of clofibric acid was found to be identical with that obtained with ethyl-alpha-p-chlorphenoxyisobutyrate (Clofibrate) reaching almost 100%. After dosage with the combination preparation, the maximum blood level of clofibric acid was achieved after 2 hours, in contrast to 4 hours for Clofibrate. No accumulation of clofibric acid in the blood was found after 60 days treatment with combination preparation at a daily dosage of 3 tablets. Urinary excretion of clofibric acid for both the combination drug and Clofibrate was 90% in 48 hours.

Adult↗