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Biomedical subjects

H Piechowiak

Publications and source records attributed to H Piechowiak.

At least 55 records · Page 3Linked to original sources
PubMed1985

IgG-antibodies to HTLV-III in patients with AIDS, LAS, and persons at risk of AIDS in West Germany.

In a first seroepidemiological study on the prevalence of the human T-lymphotropic retrovirus HTLV-III in West Germany, sera of 26 patients with acquired immunodeficiency syndrome (AIDS), 33 patients with lymphadenopathy syndrome (LAS) or AIDS related complex (ARC), and 113 homosexual men at risk of AIDS were screened for IgG antibodies to HTLV-III by an enzyme linked immunosorbent assay (ELISA). 22 out of 26 AIDS-patients (84.6%), 24 out of 33 LAS-patients (72.7%), and 44 out of 113 healthy homosexual men with increased risk of AIDS (38.9%) were found positive for antibodies to HTLV-III. Heterosexual controls including healthy laboratory workers and medical personnel with contact to AIDS patients did not show antibodies to HTLV-III. The HTLV-III antibodies analyzed predominantly recognize a protein of molecular weight 41,000 (p41).

Acquired Immunodeficiency Syndrome↗
PubMed1985

[Fetal therapy. Ethical problems as a result of prenatal diagnosis].

If a severe hereditary disease is confirmed by prenatal diagnosis, often the only "therapy" available is the termination of pregnancy or induced abortion on the grounds of genetic or "foetal" indication, a "therapy" which is of course unsatisfactory. However, now a chance of prenatal intrauterine therapy seems to be offered via the innocuous imaging methods of diagnosis, such as sonography, echocardiography, and magnetic resonance. Ethical considerations on foetal include the following problems discussed in the present article: 1. What do we know on the basis of studies conducted to date on the risk/benefit ratio? 2. How is the moral and legal status of the foetus affected by the fact that the foetus is now accessible to medical treatment? 3. What are the implications of the fact that foetal therapy is now possible, in respect of the ethical and legal assessment of termination of pregnancy? 4. What are the problems arising for the doctor with regard to his rôle as a physician who has pledged himself to help mankind, if he starts treating the foetus? 5. What are the possible implications and effects of foetal therapeutic practice on the problems of research on and with foetuses?

Abortion, Induced↗
PubMed1985

[Klein-Waardenburg syndrome. Report of 3 cases in a family with a review of the literature].

On account of a recently developed tinnitus, a young woman with the characteristic features of Klein-Waardenburg's syndrome (impairment of hearing, partial albinism, telecanthus) was hospitalised. The mother and the sister of the patient were also affected by the syndrome, albeit to a lesser degree. The otological aspects of the disease are described. Additionally, the possible association of this genetically determined disorder with certain other diseases, such as achalasia, Hirschsprung's disease or immunodeficiency, is discussed.

Abnormalities, Multiple↗
PubMed1984

[Extracorporeal fertilization and embryo transfer: a medico-ethical topic?].

In vitro fertilization and subsequent embryo transfer remains one of the most burning topical issues of medicine and medical ethics today. Like every individual ethical problem, extracorporeal fertilization initiated the question of the ethical and metaethical (anthropological) context of the origin of the problem and from which an answer may be forthcoming. The fact has to be taken into account that a uniform ethical culture is no longer possible on the grounds of the pluralism of creeds and world opinions. Ethically acceptable compromises have again and again to be looked for. However, the search for an ethical consensus of views runs the risk of being unable to keep pace with the dynamics of medical and technical progress.

Embryo Transfer↗
PubMed1983

[The Bavarian Ethics Committee. Current status in overview].

The first part of the article presents information about the history and the current work of several ethical committees at Bavarian universities (number and professional background of their members, frequency of meetings, mode of decision-making, etc.). The second part discusses the actual limited understanding of the ethical committees' function concerning experimentation with human subjects in the light of the many other ethical problems of modern medicine which could be dealt with by ethical review committees.

Ethics, Medical↗