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Biomedical subjects

H Peters

Publications and source records attributed to H Peters.

At least 181 records · Page 10Linked to original sources
PubMed1979

[Heitis terminalis promoting cancer (author's transl)].

The increasing number of publications about the incidence of cancer in small intestine with Crohn's disease shows Ileitis terminalis as an affection promoting cancer. Main problems are early diagnosis and differential diagnosis concerning intestinal stenosis caused by Crohn's recidivation or blind loop after resection. Regular scrutiny of patients with Crohn's disease is of special significance; because of the few present case reports early resection as prophylaxis is not justified.

Adenocarcinoma↗
PubMed1979

[The significance of structural changes in parenchymatous organs in ileus of the small intestine and their therapeutic consequences].

Basing on animal experiments, histologic, immune-histochemic, and laboratory examinations were performed on the purpose to investigate the injuring of parenchymatous organs in small gut ileus. Organs with primary shock could be distinguished from organs damaged by toxins, with a special position of the liver in the source area of the portal system. The course of intestinal occlusion disease is marked by comprising several circuli vitiosi. The relation between the damage of parenchymatous organs, their dysregulations, the post-agression syndrome, and the drivable therapeutic consequences are discussed. Particularly in the postoperative period the post-aggression syndrome must be paid attention to.

Animals↗
PubMed1978

[Large bowel preparation in colon surgery: elemental diet (author's transl)].

None of the usual methods of bowel preparation guarantee an aseptic large bowel. The intention is to reduce intestinal flora quantitatively, which can be achieved by mechanical cleansing alone. During the preparation period caloric and amino acid intake is insufficient. Therefore alimentation with elemental diet is necessary. The patient gets an adequate caloric and protein supply. The diet is totally absorbed in the small intestine, the large bowel remains clean, and the bacterial flora is reduced.

Colon↗
PubMed1978

Follicular growth in fetal and prepubertal ovaries of humans and other primates.

Follicular growth begins in the fetal ovary as soon as the first follicles are formed. Although orderly follicular growth is found in the fetal ovary, many of the early growing follicles show abnormalties. Follicles with irregular granulosa layers, with hypertrophied or with underdeveloped theca layers, are characteristic. Such follicles are rarely seen after birth. The ovary during childhood is an active organ in which follicular growth and follicular atresia normally take place. Follicles begin to grow at all ages, differentiate to preantral and antral follicles, but degenerate at various stages of their development before they reach pre-ovulatory sizes. Follicular growth in the fetus and children is dependent on hormones. Fetal gonadotrophins are necessary to ensure normal and sequential follicular growth before birth. During childhood a close correlation between follicle growth, hormone response and hormone production seems to exist. Certain diseases and treatment with cytotoxic agents or radiation to the abdomen influence ovarian development and follicular growth. Chromosome abnormalities, especially Turner's syndrome, trisomy 18 or 21, alter normal ovarian development by reducing the pool of available follicles and inhibiting follicular growth. Treatment with cytotoxic drugs inhibits follicular growth, while abdominal irradiation in childhood unless the ovaries are adequately shielded causes permanent damage by destroying the small follicles.

Abdominal Neoplasms↗
PubMed1978

Morphological study of the ovaries of leukaemic children.

The ovaries of leukaemic children were studied in 31 specimens obtained at autopsy. Twenty-eight ovaries from normal children of the same age who died from misadventure served as control. All ovaries from normal childred showed follicle growth and contained several large antral follicles. Follicle development was inhibited in all ovaries of leukaemic children; 22% showed no follicle growth (quiescent ovaries), and in the ovaries in which there was follicle development, the number and size of antral follicles was significantly smaller than in the control. All children had been treated with cytotoxic drugs, the duration of the treatment being correlated with the stage of ovarian development. The ovaries of children treated for only 1 week were near-normal, while those treated for more than 2 months showed inhibition of follicle growth. It is argued that the disturbance in follicle development is an effect of the cytotoxic drugs, and not an effect of the disease itself.

Acute Disease↗
PubMed1978

Follicular development in ovaries of children with Down's syndrome.

Ovaries of children with Down's syndrome were examined histologically in order to determine in what way the ovarian development differed from the normal. Twenty-six specimens obtained at autopsy at various ages between birth and 14 1/2 years were available and compared with ovaries from normal children of similar ages. All ovaries from normal children were characterized by active follicle growth. The ovaries of the children with Down's syndrome, however, showed absence or retardation of follicle growth. Furthermore the number as well as the size of the antral follicles differed from those in the normal ovary. The decrease of the number of small follicles occurs earlier in life in the ovaries of children with Down's syndrome than in the control. The possible relationship between an abnormal ovarian growth pattern and hormonal imbalance is discussed.

Adolescent↗
PubMed1978

[Ileostomy function in the early postoperative stage].

If the serosa of the protruding ileum segment is covered by mucosa [2, 3] and exclusion or resection of terminal ileum is avoided, ileostomy dysfunction or water and sodium depletion cannot be observed. Therefore, temporary loop ileostomy may be practiced in patients who have undergone ileorectostomy to prevent leakage of the anastomosis.

Humans↗
PubMed1978

[Metabolic deficiencies in gastroenterology (author's transl)].

Metabolic disturbances are one of the main reasons for complications in gastroenterologic surgery. There is a large number of inflammatory, neoplastic, and iatrogenic illnesses that cause considerable deficiencies. The intensity of disturbances depends on localization, duration, and extension of the pathologic alterations. Important for the postoperative outcome is the preoperative compensation of caloric and protein deficiencies: 1.5 g of amino acids per kg body weight/24 h and energy 160-200 joule per kg body weight/24 h.

Blood Proteins↗
PubMed1978

[Animal experiments of emptying and reflux response to terminolateral gastroduodenostomy].

The reflux and emptying mechanisms of the terminolateral gastroduodenostomy after two-thirds gastrectomy was examined in dogs. Intraluminal pressure in the gastric remnant and proximal duodenum as well as cineradiographic examinations showed that the anastomosis behaves like the intact stomach. The duodenal segment which regulates gastric emptying prevents reflux into the gastric remnant by means of rising pressure.

Animals↗
PubMed1978

[Animal experiments on the modification of fracture healing by growth hormone (STH)].

Human growth hormone seems to improve fracture healing. Using rat experiments, the clinical experiences of other authors were reviewed critically. Examination of metabolic parameters showed no useful results. Measurement of bone length and circumference and comparison of radiographs, scintigraphs, and histologic examinations indicated positive results with regard to the improvemnt of osseous consolidation when influenced by growth hormone.

Alkaline Phosphatase↗
PubMed1978

[Cryosurgical treatment of rectal carcinoma (author's transl)].

After comprehensive experimental especially morphological studies in animals, we started cryo-therapy of rectal carcinoma in 1972. We now present the first critical 5-years review concerning indication, clinical results and cryo-immunological features. In strongly indicated cases local tumour destruction by extremely low temperatures is superior to other palliative methods. Of 67 patients with rectal carcinoma treated with cryosurgery, 37 survived, 12 more than 36 months and 16 more than 24 months. Though there are only few hints indicating an increased immunological response following cryo-surgery, our investigations suggest a general influence on host's immunity by cryo-therapy.

Cryosurgery↗