[Intestinal obstruction as a complication of cholelithiasis].
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Biomedical subjects
Publications and source records attributed to H Ortiz.
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BACKGROUND: To evaluate whether treatment of the inguinal hernia in patients over 70 years has different connotations with respect to patients of a lower age. MATERIAL AND METHODS: Prospective study of 299 patients who had undergone intervention for an uncomplicated unilateral inguinal hernia during the year 2002. Group 1 included 90 patients with an age equal to, or higher than 70 years, and group 2 included the 209 patients who did not exceed this age. The variables studied in the two groups of patients were: type of hernia following the classification of Gilbert - Rutkow-Robbins, percentage of first cases-relapses, technique of repair, type of anaesthesia employed in the intervention, index of substitution in outpatient major surgery and post-operational complications. RESULTS: The two groups were similar with regard to type of hernia, surgical techniques of repair employed and type of anaesthesia employed in the intervention. In spite of the significantly greater anaesthetic risk in the group of patients of greater age (54.4% vs. 7.6% of patients ASA III; p<0.0005), significant differences were not registered between the two groups, either in the index of substitution in out-patient major surgery (80.0% vs. 81.8%) or in the development of complications (3.3% vs. 1.4%). CONCLUSION: Age is not a factor that alters the good results of the elective inguinal hernioplasty. We would thus not advise against this intervention in elderly patients.
Perianal affectation due to Crohn's disease includes a wide spectrum of lesions involving different management and prognosis. A thorough exploration of the patient, under anaesthetic if necessary, a rectoscope to evaluate the possible affectation of the rectum by the disease, and on occasions evaluation through endoanal echography or magnetic resonance, are the bases for a correct diagnostic and therapeutic focus. Pharmacology and surgery must be complementary in the treatment of perianal Crohn's disease and must pursue a double aim: to alleviate the symptomology of the patient and prevent possible complications. Except in situations of emergency due to perianal sepsis, medical treatment is the first step in managing perianal Crohn's disease, and on many occasions it will control the disease, making surgery unnecessary. When surgery is required, with the aim of a definitive treatment of the perianal lesion, the risk of developing complications, especially incontinence, must be contrasted.
The authors carried out 88 sutures of the ascending colon in Wistar rats, 44 in inversion and the remainder in eversion. The suture material used was monofilament 9/0 nylon. The intestinal diameter was measured using an instrument and the healing process studied by means of the following parameters: granulocytes, oedema, fibrin, fibroblasts and re-epithelialisation of the mucosa, on histology. The results prove that inverted sutures heal within 10 days, whereas everted sutures are not healed after 17 days. Furthermore, we demonstrated the fact that, after 72 hours, the intestinal caliber above the suture showed no appreciable differences compared with that of the normal colon.
INTRODUCTION: Alcohol withdrawal syndrome may be accompanied by severe complications, such as epileptic syndromes or delirium tremens. A number of pharmacological strategies, especially benzodiazepines (BZD), have been used in their treatment and prevention, although problems can arise from the use of these drugs due to their addictive properties. The classical anticonvulsive drugs are rarely employed as an alternative because of their side effects, but the latest generation of substances could be especially useful. AIMS. The aim of this study was to examine the safety of oxcarbazepine (OXC) in the prevention of epileptic seizures and complications deriving from the withdrawal syndrome in alcohol detoxification treatment. PATIENTS AND METHODS: The study involved a comparison of two groups of patients with a syndrome of physical dependence on alcohol, 42 of whom were treated with OXC and the remaining 42 received BZD as part of a programmed detoxification therapy. RESULTS: Both OXC and BZD were equally efficient in preventing the appearance of epileptic complications and in reducing withdrawal symptoms. Overall, OXC produced fewer adverse events (p < 0.001) and offered fewer problems when it came to ending administration (p < 0.001). CONCLUSIONS: OXC can be a valuable alternative to BZD and other pharmacological treatments in the prevention of complications in detoxification therapy, especially because of the absence of addictive properties and its having a better safety profile than classical anticonvulsant drugs.