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Biomedical subjects

H Ortiz

Publications and source records attributed to H Ortiz.

At least 37 records · Page 2Linked to original sources
PubMed1994

Does the frequency of paracolostomy hernias depend on the position of the colostomy in the abdominal wall?

The aim of this study was to determine the rate of paracolostomy hernia in relation to transrectal or pararectal position of a colostomy. Fifty-four consecutive patients who had undergone an abdomino-perineal excision for rectal neoplasia were studied. The location of the colostomy was assessed by physical examination. Computerised Tomography (CT) scanning was used in the cases where its anatomical position remained in doubt. The colostomy was in a pararectal position in 29 (54%), while in 25 (46%) it was transrectal. CT was necessary to determine the location of the colostomies in 9 cases (16%), eight of which had a parastomal hernia. The colostomy was pararectal in 15 (52%) of the 26 patients who had a paracolostomy hernia, and in 14 (48%) of the 28 patients without a paracolostomy hernia. No statistically significant correlation was found between the presence of a parastomal hernia and the position of the stoma in the abdominal wall.

Abdominal Muscles↗
PubMed1992

[Bochdalek hernia with gastric incarceration and volvulus].

Bochdalek's hernia is infrequent in adults. We communicate the case of a 22 year old male that was admitted at hospital because of a thoracic pain of sudden onset. In the exploration there was pain in left hypochondrium non tolerating decubitus. Thorax radiology showed an "arched" image in left pulmonary base and pleural shedding. The patient underwent a surgical procedure in which a great gastric herniation was found, which forced a total gastrectomy.

Adult↗
PubMed1991

Alterations in anorectal function after anterior resection for cancer of the rectum.

We have evaluated by means of a clinical and functional study the alterations in anorectal function of a group of 50 consecutive patients who have undergone an anterior resection of the rectum. Results are correlated with the anastomosis location and the time passed after the operation. According to research data this operation changes the patient's defaecation habits and the manometric and radiological parameters of anorectal function. These alterations are more evident in patients with a low anastomosis. The qualitative characteristics of defaecation did not change significantly in relation to the time passed since operation. However, there was a significant increase in compliance 6 months after operation, and the threshold rectal volume and the maximum tolerated volume also showed a significant increase 12 months following operation.

Aged↗
PubMed1991

ASTRO plenary: interfraction interval is a major determinant of late effects, with hyperfractionated radiation therapy of carcinomas of upper respiratory and digestive tracts: results from Radiation Therapy Oncology Group protocol 8313.

A prospective, randomized, multi-institutional, Phase I(LE)/II trial of HFX was conducted by the RTOG between 1983 and 1987. Patients with histologically proven, inoperable squamous cell carcinoma of the upper respiratory and digestive tracts stratified by site, nodal status, and performance status, were assigned to one of three arms, were assigned to one of three arms, 67.2 Gy, 72.0 Gy, or 76.8 Gy. Fractions of 1.2 Gy were given twice daily, 5 days per week: intervals of 4 to 8 hours were permitted between fractions. After acceptable rates of acute normal tissue effects were found, the randomization was changed to evaluate a new higher total dose, 81.6 Gy. Of 479 patients entered, 447 were analyzed, 63 on 67.2 Gy, 129 on 72.0 Gy, 117 on 76.8 Gy, and 138 on 81.6 Gy. The treatment arms were well balanced with respect to pretreatment characteristics. Acute reactions consisted almost entirely of pseudomembranous inflammation. "Severe" (Grade 3) acute reactions were reported in 33% to 41% and grade 4 reactions were found in 0 to 3% of patients, with no differences in frequencies among the four arms. Toxicities that developed or persisted beyond 90 days after the first treatment (408 patients evaluable greater than 90 days) did not differ among arms: grade 3+ reactions occurred in 10% to 14%, and grade 4+ effects (necroses) were reported in 5% at 67.2 Gy, 3% at 72.0 Gy, 7% at 76.8 Gy, and 2% at 81.6 Gy. Grade 3+ acute reactions occurred in 40% of patients when the interfraction interval was less than or equal to 4.5 hours versus 31% with greater than 4.5 hours (p = .03). Interfraction intervals less than or equal to 4.5 hours were associated with higher frequencies of grade 4+ late effects in all four arms, 8% of 197 patients with less than or equal to 4.5 hours versus 1% of 211 patients with greater than 4.5 hours. Estimates of late toxicity at 1, 2, and 3 years were 5.5%, 9.8%, and 15.4% with intervals less than or equal to 4.5 hours, versus 1.7% at all three periods for greater than 4.5 hours (p = .006). Local-regional control at 2 years was 25% for the assigned dose of 67.2 Gy compared to 43% to 45% for the three higher doses (p = .01), but a similar comparison for survival showed no significant difference (p = .35). There was no evidence for an effect of interfraction interval on either local-regional control (p = .38) or survival (p = .28).(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗
PubMed1987

Hair-containing lesions within the anal canal.

Hair-containing lesions located in the anal canal are an exceedingly rare clinical entity of which only five cases have been reported previously. We add five more cases, including two with a bundle of hairs rooted inside the anal canal and stemming out through a mucosal opening.

Adult↗
PubMed1985

Protocol variations and their influence on the final outcome: critical review of the split-course base of tongue study of the RTOG.

A critical review of the protocol variations in an RTOG prospective randomized multi-institutional clinical trial has been conducted. The objective of the review was to identify variables that might have affected the results of the study. Compliance with general guidelines and specific technical treatment parameters of the Split-Course Radiation Therapy Protocol for Carcinoma of the Base of the Tongue (RTOG #71-02) was analyzed. A +/- 5% variation of the time-dose-fractionation factors, using the NSD and TDF formulae and their respective protocol ratios (ratio between actual case NSD and TDF level and what the protocol recommended), has been defined as fully acceptable. Seventy-two percent of the 141 study cases were within this category. Minor variation has been defined as one resulting in a +/- 6% to +/- 15% deviation from the study values (15.3% of cases). Major and unacceptable variation was a deviation of +/- 16% or more from the research plan (12.7% of cases). After identifying the different variations and correlating them with the clinical results, we conclude that these deviations did not affect the final results to a significant or identifiable degree.

Clinical Trials as Topic↗
PubMed1983

Split-course radiation therapy of carcinoma of the base of the tongue: results of a prospective national collaborative clinical trial conducted by the Radiation Therapy Oncology Group.

One hundred forty-one patients with carcinoma of the base of tongue were randomized to receive either continuous course radiotherapy (6600 rad in 30/33 fractions over 7-8 weeks) or split course therapy (3000 rad in 10 fractions over 2 weeks, a three-week rest, 3000 rad in 10 fractions over 2 weeks). Both treatment groups tolerated the treatment well, but the continuous course group required more treatment modifications. The results of therapy, as judged by control of primary tumor, control of metastatic lymph nodes, time to failure and overall survival were comparable in the two treatment groups.

Aged↗
PubMed1976

Carcinoids of the first part of the duodenum.

Three cases of duodenal carcinoid tumour are described and the histology of this type of tumour is discussed. Two of the patients have been followed up for 8 years. No further complications related to the tumours have been observed.

Aged↗
PubMed1975

Intraosseous leptomeningeal cysts of the posterior cranial fossa.

Post-traumatic leptomeningeal cysts involving the occipital bone are intraosseous lesions which do not erode through the outer table, in contradistinction to leptomeningeal cysts elsewhere in the calvaria. In two of four reported cases, communicating hydrocephalus was associated with the intraosseous cyst. The clinical and radiological findings suggest that intraosseous leptomeningeal cyst of the posterior fossa represents a distinct entity. Resection of the cyst and closure of the dural defect may be less important than treatment of the communicating hydrocephalus.

Adult↗