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Biomedical subjects

H Ohno

Publications and source records attributed to H Ohno.

At least 577 records · Page 32Linked to original sources
PubMed1983

[Anti-inflammatory effect of Cu-Zn superoxide dismutase on carrageenin-induced arthritis in rabbits].

Anti-arthritic action of superoxide dismutase (SOD) was studied in rabbits. Arthritis was induced by intraarticular injections of lambda-carrageenin (1%, 1 ml) into the knee joint weekly for two weeks. In this experimental arthritis, acid phosphatase activity, quantities of protein, uronic acid and lipid peroxide, and leukocyte counts in the synovial fluid increased; and the quantity of uronic acid in the articular cartilage decreased. Microscopic findings of the synovial membrane showed a proliferative synovitis. The responses of the left and right knee joint to carrageenin were much to the same in degree, so that the anti-arthritic action of SOD by intraarticular injections was evaluated on one knee joint, referring to the other joint as a control (saline injections). Two injections of SOD (350 SOD unit = 0.1 mg), one a week, suppressed the inflammatory changes in the biochemical parameters of the synovial fluid and the articular cartilage; particularly, significant inhibitory effects on acid phosphatase, lipid peroxide and leukocyte were observed. The microscopic findings of the synovial membrane also revealed that SOD was efficacious. On the other hand, 0.1 mg of denatured SOD, prepared by reducing the S-S bond or heating under an alkaline condition, did not show any anti-arthritic activity. These results suggest that the anti-arthritic action of SOD actually depends on the enzymatic activity of superoxide dismutase.

Acid Phosphatase↗
PubMed1982

Effects of phase transformations of silicas and calcium sulfates on the compressive strength of gypsum-bonded investments at high temperatures.

The effects of transformations of silicas and calcium sulfates on high temperature compressive strength were investigated in commercial and experimental investment materials containing fused quartz as silica. The strength is only slightly affected by the alpha leads to beta transformation of cristobalite and not by the quartz alpha leads to beta transformation. The state of the calcium sulfates is the main factor influencing variations in the strength at a particular temperature.

Calcium Sulfate↗
PubMed1982

The structure of oxide formed by high-temperature oxidation of commercial gold alloys for porcelain-metal bonding.

For gold alloys containing only In as a base metal, an external In2O3 layer forms uniformly on the alloy surface. However, when the alloy contains Sn and In, no external oxide layer can be detected by electron probe micro-analysis, and oxide particles composed of In2O3 and SnO2 precipitate in the alloy. For alloys containing Ni, in addition to In and Sn, the external oxide is composed of NiO; there is little development of internal oxide. For alloys containing Fe and Sn, an oxide layer of only Fe2O3 forms on the alloy surface, and the internal oxidation zone shows a band-like structure containing SnO2 and a small amount of Fe2O3.

Chemical Phenomena↗