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Biomedical subjects

H Nishimura

Publications and source records attributed to H Nishimura.

At least 937 records · Page 52Linked to original sources

Renin, cortisol and plasma volume in marine teleost fishes adapted to dilute media.

The renin-angiotensin system has been found in teleost fishes from both marine and fresh-water environments. In an attempt to define whether activity of the renin-angiotensin system is related to sodium balance in fishes, we transferred two euryhaline teleosts from seawater to hypo-osmotic media. Plasma renin activity decreased in American eels, Anguilla rostrata, after they were transferred from seawater to fresh water, and it did not change in the aglomerular toadfish, Opsanus tau, after transfer from 50% seawater to 5% seawater. Plasma sodium concentrations decreased significantly in toadfish in 5% seawater and in one group of eels in fresh water. Plasma levels of cortisol, a major mineralocorticoid in teleosts, and plasma volume, measured in eels, remained relatively constant. There are no clear correlations between plasma renin levels and those of plasma sodium or plasma cortisol. These results provide no evidence that the need of these fishes to conserve sodium when in hypo-osmotic media stimulates the renin-angiotensin system.

Adaptation, Physiological↗

Occurrence of alpha-fetoprotein, Regan isoenzyme, and variant alkaline phosphatase in the serum of a patient with gastric cancer.

Regan isoenzyme, variant alkaline phosphatase, and alpha-fetoprotein were found in the serum of a patient with gastric cancer. The histology of the tumor was tubular adenocarcinoma. There were metastases in the retroperitoneal lymph nodes, but not in the liver. The liver was normal microscopically, with no evidence of bile duct obstruction. alpha-Fetoprotein in the tumor tissue was detected by immunoprecipitation reaction in agar. Regan isoenzyme and variant alkaline phosphatase were also detected in the tumor tissue and total alkaline phosphatase activity of the tissue was very high. These findings suggested their tumor origin.

Adenocarcinoma↗

[Multiple intracranial mycotic aneurysm. Report of a case (author's transl)].

A case of intracranial mycotic aneurysm was reported, in whom repeated cerebral angiographies demonstrated the seccessive appearance of multiple aneurysms in a short term after the septic cerebral infection, and the importance of repeated angiography in the treatment of the intracranial mycotic aneurysm was stressed. A 44-year old male who had heart failure developed suddenly a left hemiparesis with irritable meningial signs on Nov. 3, 1973. The right carotid angiography carried out on Nov. 16 in an admitted hospital showed partial obliteration of cortical branches of the middle cerebral shift of the anterior cerebral artery due to the cerebral infarction. No aneurysm was demonstrated in the angiogram. The second angiography of the right carotid and vertebral artery was done on the admission of Dec. 18. The previously shown contralateral shift of the anterior cerebral artery was remarkably decreased, and an aneurysm of 3 mm in diameter was recognized at the cortical branch of the right middle cerebral artery on the parietal region. Any aneurysm was not revealed by the vertebral angiography. The third angiography of bilateral carotid and vertebral artery was performed on Dec. 25. The previously revealed aneurysm increased in size. Multiple aneurysms was demonstrated at the anterior branches of the insular artery. The vertebral angiography demonstrated multiple aneurysms at the peripheral portion of the bilateral posterior cerebral arteries. The patient was improved neurologically after the administration of antibiotics, and was discharged on Dec. 27 on the convenience of his family and would be followed in conservative cares.

Adult↗