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Biomedical subjects

H Narchi

Publications and source records attributed to H Narchi.

At least 55 records · Page 3Linked to original sources
PubMed1999

Is gastric lavage needed in neonates with meconium-stained amniotic fluid?

UNLABELLED: We compared the incidence of complications from meconium-containing gastric fluid in a group of neonates born with meconium-stained amniotic fluid (MSAF) who did not routinely have gastric lavage prior to feeds, versus a group who had elective gastric lavage before the first feed. In the first group, 275 neonates born with MSAF were fed without prior gastric lavage. While 13 developed feeding problems, the other 262 infants (95%) who did not undergo routine gastric lavage remained free of later feeding difficulties or secondary meconium aspiration. In the second group, all 227 neonates with MSAF had elective gastric lavage performed after birth. All remained free of later feeding difficulties or secondary meconium aspiration. CONCLUSION: Our data suggest that gastric lavage is not necessary in most neonates born with meconium-stained amniotic fluid, regardless of the thickness of the meconium-stained fluid, as no complications from meconium-containing gastric fluid were observed.

Amniotic Fluid↗
PubMed1999

Neonatal ECG screening for congenital heart disease in Down syndrome.

We studied the value of routine neonatal electrocardiography (ECG) in the 1st 48 hours of life to diagnose congenital heart disease in 37 neonates with Down syndrome. Twenty-four infants had no clinical evidence of congenital heart disease, had normal ECGs and normal cardiac anatomy on echocardiography. Thirteen children (35.2%) had congenital heart disease. The ECG was normal in seven infants with congenital heart disease: four with atrial septal defect (ASD), two with tetralogy of Fallot (TOF) and one with ventricular septal defect (VSD). A left QRS axis deviation was found in six infants: five with complete atrioventricular septal defect (AVSD) and one with VSD and mitral valve prolapse. However, only the five infants with complete AVSD had a superior QRS axis. Although neonatal ECG detected the presence of complete AVSD in neonates with Down syndrome, it missed an equal number with other heart defects. Echocardiography remains the way reliably to diagnose or exclude congenital heart disease in these infants.

Down Syndrome↗
PubMed1998

Maternal sickle cell anemia and neonatal isoimmunization.

OBJECTIVE: To study the risk of alloimmunization in pregnant women with sickle cell disease (SCD) and of isoimmunization in their offspring. METHOD: Thirty mothers with SCD were studied and their 35 neonates (group 1) were compared with 538 infants of mothers without hemoglobinopathies (group 2). RESULT: Six mothers with SCD developed alloantibodies. There was no correlation with maternal age (P = 0.6), parity (P = 0.18) or blood transfusions (P = 0.4). The risk of alloimmunization by transfusion was 20%. Six neonates were isoimmunized, a higher incidence than in group 2 (P = 0.02; relative risk 3.07). Five had ABO incompatibility and only one had anti-c isoimmunization. All had reticulocytosis, jaundice and required phototherapy, one developed anemia but none required blood transfusion. CONCLUSION: Although alloimmunization was common in mothers with SCD and isoimmunization in their offspring, it was rarely due to non-ABO alloantibody. There was no significant neonatal morbidity.

Adult↗