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Biomedical subjects

H Narchi

Publications and source records attributed to H Narchi.

At least 37 records · Page 2Linked to original sources
PubMed2000

A painful limp.

We describe a healthy 18-month-old child who developed a painful limp, without a history of trauma or fever. The initial laboratory investigations showed normal results but the radiological findings were suggestive of scurvy. Diagnosis was confirmed by blood tests and by a rapid recovery following replacement therapy.

Ascorbic Acid↗
PubMed2000

Osteomyelitis in sickle cell haemoglobinopathy with elevated fetal haemoglobin.

The prevalence rate and characteristics of osteomyelitis in children below 15 years of age were studied in a population characterized by a high prevalence of sickle cell disease (SCD) with elevated fetal haemoglobin (HbF). All children born in our institution routinely undergo a haemoglobinopathy screening test. Osteomyelitis developed in 25 children (16 boys and nine girls) with a mean age of 5.5 years. Fourteen had sickle cell disease (SCD) and 11 had no haemoglobinopathy. The prevalence of osteomyelitis in children with SCD was 69 times higher than in those without (283 vs 4/10(5)). All 14 children with SCD and osteomyelitis also had elevated HbF. Three children had HbS alpha-thalassaemia, with mean HbF 24% and HbS 68.6%. Eleven children had sickle cell anaemia with elevated HbF, mean HbF 31.7% and HbS 66.7%. There was no significant difference in symptoms, signs, leucocyte, neutrophil and band counts, nor in sedimentation rates. Salmonella organisms were significantly more frequently responsible for osteomyelitis in SCD. The presence of elevated HbF in children with SCD should not lead to complacency as they are still at increased risk of developing osteomyelitis.

Adolescent↗
PubMed2000

Case-control study of diet and sun exposure in adolescents with symptomatic rickets.

Dietary intake and sun exposure were compared in a case-control study of 14 adolescent girls diagnosed to have symptomatic nutritional rickets with hypocalcaemia, hypophosphoraemia, elevated serum alkaline phosphatase and serum parathormone and reduced 25-hydroxy vitamin D levels and 20 controls without clinical rickets (ten girls) of the same age group and socio-economic background. In the control group, calorie intake was reduced in seven boys and eight girls, dietary calcium in seven boys and seven girls and vitamin D in six boys and eight girls. All 20 adolescents of both sexes were exposed to the sun for more than 60 min a day. In the group with rickets, calorie intake was reduced in 11 girls, calcium in 14 girls and vitamin D in nine girls). Sun exposure was significantly less in girls with rickets than in controls (p < 0.001). Adolescents in our population, especially females, are at high risk of developing nutritional rickets. Prevention by longer exposure to the sun is simple and cheap but when not practical for social or cultural reasons routine vitamin D supplementation might be indicated.

Adolescent↗
PubMed2000

A twelve year study of the incidence of childhood type 1 diabetes mellitus in the Eastern Province of Saudi Arabia.

OBJECTIVE: Study of the incidence of childhood type 1 diabetes in the Eastern Province of Saudi Arabia. METHODS: Analysis included all children eligible for care in our hospital who had type 1 diabetes diagnosed before their 15th birthday between 1986 and 1997. RESULTS: A total of 46 children (27 girls and 19 boys) were identified, with a median age at diagnosis of 10.3 yr. The overall age-adjusted incidence rate was 12.3 x 10(5)/yr; it was 9.9 x 10(5)/yr for males and 14.8 x 10(5)/yr for females. The number of patients increased significantly (relative risk of 46) over the study period (p=0.01), more significantly in females (p=0.007) and in the 10-14 year age group (p=0.01). CONCLUSIONS: The incidence of type 1 diabetes increased markedly over the past 12 years, mainly in females and children over 10 years of age. The data confirm the need to develop a national registry and the need for further epidemiological research.

Adolescent↗