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Biomedical subjects

H Muto

Publications and source records attributed to H Muto.

At least 109 records · Page 6Linked to original sources

[Radiotherapy combined with pepleomycin administration for the treatment of esophageal cancer].

A combined therapy of pepleomycin (NK-613) and radiation was performed in 15 cases of esophageal and cancer. Twelve cases out of 15 were inoperable, and 3 cases were operable. NK-631 was administered by drip intravenous injection at a dose of 5 mg per day for 3 consecutive days weekly, aiming at total dose of 60-120 mg. Tumor regression rates, which were measured by planimeter on esophagogram, were 42-92% (mean 72%): two cases were more than 90%, and more than 50% in 12 cases. An average of the survival period of 15 cases was 57 weeks with 7 cases (46.7%) of 1 year survival, 2 cases (13.3%) of 2 year survival. The side effects of NK-631 observed in the present study consisted of fever 6, stomatitis 2, skin rash 2, and reversible pneumonitis 2. This study suggests that NK-631 exhibit remarkable anti-tumor effects on esophageal carcinoma, and seem to be less toxic.

Aged↗

Fine structure of the fully keratinized hair cuticle in the head hair of the human.

The cuticle is composed of five cell layers in the cross section of the hair at a level of 100 mm above the scalp. Intercellular junctions between two cuticular cells are zonulae occludentes (tight junction); they consist of five layers. The gap junctions of the intercellular communications occur near the cortex. The trichohyalin granule appears in the cuticular cells of completely cornified head hair. The granule is generally smaller than that of the keratohyalin granule, and spherical in shape. The granule is not visible in the area near the surface of the hair. The keratin in the cytoplasm of the cuticular cell may originate from the trichohyalin granule.

Adult↗

Early cancer of the stomach treated successfully with an endoscopic neodymium-YAG laser: report of a case.

A 61-year old man with poor pulmonary function was seen with two early cancers of the stomach. Neodymium-YAG laser treatment was applied to these lesions since surgery was contraindicated. The lesions were treated four times. Both tumors completely disappeared and the patient was left with ulcer scars that formed three to seven months after the treatment. Our results suggest that endoscopic Nd-YAG laser therapy is applicable in the treatment of early gastric cancer when a surgical operation is contraindicated.

Adenocarcinoma↗