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Biomedical subjects

H Murata

Publications and source records attributed to H Murata.

At least 289 records · Page 16Linked to original sources

Congenital stenosis involving a long segment of the trachea: further experience in reconstructive surgery.

Since we introduced the surgical technique for the repair of congenital stenosis involving the entire trachea with a successfully treated patient in 1982, four more patients have undergone a tracheoplasty employing the same technique for congenital stenosis involving a long segment of trachea. This article describes the refinement of surgical technique, the management of patients during and after operation, and the long-term outcome.

Female↗

[The method for stress assessment of workers (Part 1). Stress score by self-rating method].

In order to evaluate the grade of reaction to stressors, especially those on occupational life of workers, the following stress survey was conducted. Eighteen new items of occupational life stressors were proposed in addition to the social readjustment rating scale (S.R.R.S.) prepared by Holmes. Furthermore, two items, "own stress tolerance" and "own stress at present," were designed in addition to the foregoing 65 stressors. Marriage is given a score of 50 in reference-standard of stress strength. These 67 items of 1,630 workers were evaluated by the self-rating method ranging in score from 0 to 100. The results can be summarized as follows: 1. As for each item, we examined the average value of the total sample and analyzed them by sex, age, kind of occupation, position, and length of service. We named these stress scores and analyzed the ranking of 65 stress scores. The item with the highest score was "death of spouse (score 82.7)" and the item with the lowest one was "income increase (score 24.7)." The scores of 27 out of 65 items were higher than 50. Next, 65 items were classified into 4 groups, that is, individual life, family life, occupational life, and social life. 2. Scores of the newly designed items to examine the ability to adjust oneself to place of work were "own stress tolerance (score: 73.7)" and "own stress at present (48.8)," respectively. 3. We examined the difference by sex, age, kind of occupation, position, and length of service based on the average value of stress score by t-test and the following results were obtained. 1) Scores of those in the thirties were higher than those in the twenties. 2) Section heads and leaders were under greater stress than division heads. In the same way, the differences among the four groups were analyzed and the following results were observed. 1) The only significant difference was seen in the occupational life stress group. 2) In the occupational life stress group, the scores of those in the thirties, forties, and fifties were higher than those in the twenties. Section heads and leaders were under greater stress than the staff. Workers in service for more than 21 years had higher scores than workers in service for less than 10 years. 4. The practical uses of our stress survey are also discussed in this report.

Adult↗

Clinical features of a newly recognized type of lattice corneal dystrophy.

We examined five patients with an undescribed type of lattice corneal dystrophy. All patients were in the seventh to ninth decades of life and had developed decreasing vision late in life. None of the patients had suffered from recurrent epithelial erosions, there was no overt evidence of systemic amyloidosis, and the lattice lines were much thicker than those usually observed in lattice corneal dystrophy types I and II. Available pedigree data from two families of three patients indicated that the corneal disorder affected several siblings but not the parents or offspring. Two patients had no affected family members. There was no known consanguinity in any of the four families.

Adult↗

Lattice dystrophy type 1: a report of 8 families.

Eight families with lattice corneal dystrophy are reported. The symptoms and signs are almost identical with the typical lattice corneal dystrophy type 1 in western countries. Lattice corneal dystrophy has been considered to be a rare disease until recently, but it might be a more common disorder. This is the first report of a large series of lattice corneal dystrophy in Japan.

Adolescent↗

A clinicopathologic correlation study of thallium-201 myocardial scintigraphy in diagnosis of myocardial infarction.

In a series of 1,000 consecutive autopsy cases, we evaluated the clinical utility of thallium-201 (Tl-201) myocardial scintigraphy and electrocardiography (ECG) in 101 patients who had been studied while alive. Fifty-five cases had myocardial infarctions (MI) at autopsy. The Tl-201 scintigram and ECG in diagnosis of MI showed sensitivities of 68% and 60%, specificities of 87% and 83%, and diagnostic accuracies of 76% and 70%, respectively. The sensitivity of the Tl-201 scintigram was 70% in anterior MI, 80% in postero-inferior MI, 25% in lateral and subendocardial infarction. The sensitivity was 88% for large massive MI, but was low in scattered (50%) or middle-sized MI (17%). The diagnostic limit of the resolution of Tl-201 scintigrams was 4.5 cm in long diameter. All 8 cases with MI of less than 4 cm could not be diagnosed with the technique. There were 48 cases of large MI (more than 5 cm), but 8 cases could not be diagnosed by scintigraphy because of non-transmural or scattered MI. A comparison of the Tl-201 scintigram and ECG showed that 27 cases out of 60 cases were diagnosed by both methods, 14 only by the Tl-201 scintigram, 9 only by ECG and 10 by neither method.

Aged↗

The pathogenesis of experimental arteritis induced by Candida alkali-extract in mice.

The pathogenesis of experimental arteritis induced by Candida alkali-extract in mice was studied from the immunological, pharmacological and chemical points of view. The following results were obtained. 1) The incidence of arteritis increased in parallel with IgE antibody level of Candida, as shown by the PCA method. 2) Candida polysaccharide showed cardiotonic, coronary vasodilatatory and vasoconstrictive activities on Langendorff's and spiral preparation of rats. 3) Candida polysaccharide was shown to contain digitoxose by gas-mass spectrometry. From these results, it is suspected that this extract reacts on experimental animals by the toxic and immunological mechanisms, and that these mechanisms may be related to the occurrence of arteritis.

Animals↗

Evaluation of regurgitant fraction of the left ventricle by gated cardiac blood-pool scanning using SPECT.

Regurgitant fraction (RF) of patients with and without mitral regurgitation (MR) and/or aortic regurgitation (AR) was evaluated by gated cardiac blood-pool scanning using single photon emission computed tomography (SPECT). Using the stroke count image of a short-axis tomogram to separate the right atrium and ventricle, the left ventricular stroke count (LVSC) and right ventricular stroke count (RVSC) were determined. The RF equaled (LVSC - RVSC)/LVSC. Calculated RF in 14 subjects without significant regurgitation by contrast angiography was 5.8 +/- 5.9% (mean +/- s.d.), RF of 17 cases with angiographic regurgitation was 42.5 +/- 16.8% (p less than 0.001). The sensitivity of the radionuclide method compared to angiography was 94% (16/17 cases), and specificity was 100% (14/14 cases). RF of mild Re (1+ or 2+) was 26.0 +/- 8.9% (n = 6) and RF of severe Re (3+ or 4+) was 51.5 +/- 12.7% (n = 11) (p less than 0.001). Correlation between the RF determined with the radionuclide method and with cardiac catheterization was good (y = 5.85 + 0.700 x, r = 0.821, n = 17). We conclude that RF of MR and/or AR can be accurately evaluated by gated cardiac blood-pool scanning using SPECT.

Cardiac Catheterization↗