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Biomedical subjects

H Moriyama

Publications and source records attributed to H Moriyama.

At least 235 records · Page 13Linked to original sources

The mechanism of inhibition of caloric nystagmus by eye closure.

24 normal adults and 324 clinical cases were examined, for the purpose of shedding light on the mechanism of inhibition of caloric nystagmus by eye closure. When the eyes were closed, an eye was suddenly adducted 13 +/- 5 degrees and elevated 55 +/- 11 degrees. These adductive and upward eye movements were normal responses caused by eye closure. Caloric nystagmus was inhibited by upward eye deviation. With the turning down of the vertical eye position, the caloric-nystagmus inhibition was released. During eye closure, there were four types of vertical eye-movement responses: (a) holding the eye position up, (b) fluctuation around an upward eye position, (c) gradual downward turning, (d) sudden downward turning, Types a, b and c were seen in normal subjects. However, type d was not seen in normal people.

Caloric Tests↗

Analysis of herpes simplex virus isolated from patients with recurrent herpes keratitis exhibiting "treatment-resistance" to 5-iodo-2'-deoxyuridine.

Four strains of herpes simplex virus (HSV) were isolated from two patients with recurrent herpes keratitis who failed to respond to 5'-iodo-2'-deoxyuridine (IDU) treatment. Two of the four isolates were highly resistant to IDU in cell culture and the other two isolates were more susceptible to IDU than an HSV-1 laboratory strain. From each patient, an IDU-resistant and an IDU-susceptible virus was isolated. All 4 isolates possessed the ability to induce the thymidine kinase (TK) activity in cell lines lacking that activity. All the isolates were type 1 HSV, since the filamentous structures, recognized as a biological marker of type 2 HSV, were not observed in infected cells.

Animals↗