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Biomedical subjects

H Mikami

Publications and source records attributed to H Mikami.

At least 307 records · Page 17Linked to original sources
PubMed1978

[Nasal route flexible broncho-fiberscopy, as a tool of mass examination for hilar type lung cancer (author's transl)].

Early detection of lung cancer is mandatory problem in the medical field. Although, chest x-p examination is a strong armament for detection of peripheral type of lung cancer, the method has rather weak point in detection of hilar type of bronchogenic carcinoma. Bronchoscopy is essential method for diagnosis of bronchial changes of this disease. It is, however, not popular method yet, because of its troublesome technique, such as insertion of tracheal tube, eventhough new instrument of flexible fiber bronchoscopy makes us very much easy way to use, compared with old-fashioned rigid bronchoscopy. For mass examination of high risk group of bronchogenic carcinoma (chromate workers), we are using nasal route flexible fiberbronchoscopy. Comparing of this method with previously used trans-oral route, both easiness of the technique on doctor's side, and comfort during the examination on the patients's side revealed favorable results for nasal method.

Bronchoscopy↗
PubMedDate not supplied

Effect of ouabain on hemodynamics in acute volume expanded hypertensive dogs.

To evaluate possible roles of endogenous Na+-K+-ATPase inhibitors in vasoconstricted blood pressure elevation produced by acute volume expansion, we administered ouabain (Na+-K+-ATPase inhibitor) intravenously (30 micrograms/kg) for 10 min to dogs, 3 h after volume expansion with dextran in lactated Ringer's solution (20 ml/kg, for 1 h). Acute volume expansion resulted in the elevation of blood pressure associated with an increase in cardiac output. In some dogs the blood pressure remained elevated with gradual increase in total peripheral resistance (Group I) or with sustained high cardiac output (Group II), and in other dogs (Group III) it returned to the control level. Ouabain administration elevated the blood pressure and total peripheral resistance in these groups and sham dogs which did not have volume expansion. And these effects of ouabain were not correlated with the degree of blood pressure or vasoconstriction produced by volume expansion. Thus, it is not likely that endogenous Na+-K+-ATPase inhibitors increased to produce vasoconstricted hypertension after acute volume expansion.

Animals↗